rs17016316

Homo sapiens
A>G
None
Check p-value
SNV (Single Nucleotide Variation)
G=0082 (2458/29974,GnomAD)
G=0073 (2129/29118,TOPMED)
G=0143 (718/5008,1000G)
G=0055 (213/3854,ALSPAC)
G=0048 (178/3708,TWINSUK)
chr4:89876084 (GRCh38.p7) (4q22.1)
ND
GWASdb2
1   publication(s)
See rs on genome
30 Enhancers around
36 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 4NC_000004.12:g.89876084A>G
GRCh37.p13 chr 4NC_000004.11:g.90797235A>G
MMRN1 RefSeqGeneNG_032895.2:g.1553A>G

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322A=0.897G=0.103
1000GenomesAmericanSub694A=0.880G=0.120
1000GenomesEast AsianSub1008A=0.771G=0.229
1000GenomesEuropeSub1006A=0.939G=0.061
1000GenomesGlobalStudy-wide5008A=0.857G=0.143
1000GenomesSouth AsianSub978A=0.790G=0.210
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854A=0.945G=0.055
The Genome Aggregation DatabaseAfricanSub8732A=0.913G=0.087
The Genome Aggregation DatabaseAmericanSub838A=0.870G=0.130
The Genome Aggregation DatabaseEast AsianSub1604A=0.789G=0.211
The Genome Aggregation DatabaseEuropeSub18498A=0.933G=0.066
The Genome Aggregation DatabaseGlobalStudy-wide29974A=0.918G=0.082
The Genome Aggregation DatabaseOtherSub302A=0.950G=0.050
Trans-Omics for Precision MedicineGlobalStudy-wide29118A=0.926G=0.073
UK 10K study - TwinsTWIN COHORTStudy-wide3708A=0.952G=0.048
PMID Title Author Journal
17158188Novel genes identified in a high-density genome wide association study for nicotine dependence.Bierut LJHum Mol Genet

P-Value

SNP ID p-value Traits Study
rs170163160.000586nicotine dependence17158188

eQTL of rs17016316 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs17016316 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr49075549090756365E067-40870
chr49075549090756365E069-40870
chr49083708590837178E06939850
chr49083718390837427E06939948
chr49082759290827668E07030357
chr49082813990828226E07030904
chr49082830990828413E07031074
chr49083587990836411E07038644
chr49083645690836506E07039221
chr49083657390836723E07039338
chr49083680090836853E07039565
chr49083708590837178E07039850
chr49083718390837427E07039948
chr49083680090836853E07139565
chr49083708590837178E07139850
chr49083718390837427E07139948
chr49075549090756365E072-40870
chr49075061890751132E073-46103
chr49075549090756365E074-40870
chr49075549090756365E081-40870
chr49083587990836411E08138644
chr49083645690836506E08139221
chr49083657390836723E08139338
chr49083680090836853E08139565
chr49083708590837178E08139850
chr49083718390837427E08139948
chr49083587990836411E08238644
chr49083645690836506E08239221
chr49083657390836723E08239338
chr49083680090836853E08239565









Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr49075711390757163E067-40072
chr49075724390759545E067-37690
chr49075955390759654E067-37581
chr49075678390757088E068-40147
chr49075711390757163E068-40072
chr49075724390759545E068-37690
chr49075678390757088E069-40147
chr49075711390757163E069-40072
chr49075724390759545E069-37690
chr49075955390759654E069-37581
chr49075711390757163E070-40072
chr49075724390759545E070-37690
chr49075955390759654E070-37581
chr49075678390757088E071-40147
chr49075711390757163E071-40072
chr49075724390759545E071-37690
chr49075678390757088E072-40147
chr49075711390757163E072-40072
chr49075724390759545E072-37690
chr49075955390759654E072-37581
chr49075678390757088E073-40147
chr49075711390757163E073-40072
chr49075724390759545E073-37690
chr49075955390759654E073-37581
chr49075678390757088E074-40147
chr49075711390757163E074-40072
chr49075724390759545E074-37690
chr49075955390759654E074-37581
chr49075678390757088E081-40147
chr49075711390757163E081-40072
chr49075724390759545E081-37690
chr49075955390759654E081-37581
chr49075678390757088E082-40147
chr49075711390757163E082-40072
chr49075724390759545E082-37690
chr49075955390759654E082-37581