SNP Detail Info-rs17019859

Organism: Homo sapiens

Alleles: G>A

Gene : Feature

None

p-value: Check p-value

Variation Type: SNV (Single Nucleotide Variation)

Frequency:

A=0191 (5728/29976,GnomAD)
A=0204 (5963/29116,TOPMED)
A=0199 (999/5008,1000G)
A=0132 (507/3854,ALSPAC)
A=0136 (505/3708,TWINSUK)

Position: chr2:80898111 (GRCh38.p7) (2p12)

Phenotype: ND

Dataset:

GWASdb2

Publications: 1 publication(s)

Genomic View: See rs on genome

Enhancer: 6 Enhancers around

Promoter: 0 Promoter around

Sequence Name	Change(s)
GRCh38.p7 chr 2	NC_000002.12:g.80898111G>A
GRCh37.p13 chr 2	NC_000002.11:g.81125236G>A

Study	Population	Group	Sample #	Ref Allele	Alt Allele
1000Genomes	African	Sub	1322	G=0.658	A=0.342
1000Genomes	American	Sub	694	G=0.850	A=0.150
1000Genomes	East Asian	Sub	1008	G=0.765	A=0.235
1000Genomes	Europe	Sub	1006	G=0.881	A=0.119
1000Genomes	Global	Study-wide	5008	G=0.801	A=0.199
1000Genomes	South Asian	Sub	978	G=0.910	A=0.090
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	G=0.868	A=0.132
The Genome Aggregation Database	African	Sub	8718	G=0.701	A=0.299
The Genome Aggregation Database	American	Sub	838	G=0.860	A=0.140
The Genome Aggregation Database	East Asian	Sub	1620	G=0.817	A=0.183
The Genome Aggregation Database	Europe	Sub	18498	G=0.856	A=0.143
The Genome Aggregation Database	Global	Study-wide	29976	G=0.808	A=0.191
The Genome Aggregation Database	Other	Sub	302	G=0.860	A=0.140
Trans-Omics for Precision Medicine	Global	Study-wide	29116	G=0.795	A=0.204
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	G=0.864	A=0.136

PMID	Title	Author	Journal
17158188	Novel genes identified in a high-density genome wide association study for nicotine dependence.	Bierut LJ	Hum Mol Genet

SNP ID	p-value	Traits	Study
rs17019859	0.000181	nicotine dependence	17158188

Position (v37)	eGene	GeneID	Variant	p-value	TSS	Tissue
There is no eQTL annotation for this SNP

Probe ID	Position	Gene	beta	p-value
There is no meQTL annotation for this SNP

Chromosome	Start	End	Region	Distance ( -/+ : Up/Downstream )
chr2	81120984	81121044	E070	-4192
chr2	81121593	81122042	E070	-3194
chr2	81120984	81121044	E071	-4192
chr2	81121593	81122042	E071	-3194
chr2	81120984	81121044	E074	-4192
chr2	81121593	81122042	E074	-3194

rs17019859