SNP Detail Info-rs17028615

Organism: Homo sapiens

Alleles: A>G

Gene : Feature

LOC100507053 : Intron Variant

p-value: Check p-value

Variation Type: SNV (Single Nucleotide Variation)

Frequency:

G=0063 (1888/29990,GnomAD)
G=0103 (2998/29118,TOPMED)
G=0063 (317/5008,1000G)
G=0001 (3/3854,ALSPAC)
G=0001 (2/3708,TWINSUK)

Position: chr4:99150767 (GRCh38.p7) (4q23)

Phenotype: AD

Dataset:

GWASCatalog

Publications: 2 publication(s)

Genomic View: See rs on genome

Enhancer: 0 Enhancer around

Promoter: 0 Promoter around

Sequence Name	Change(s)
GRCh38.p7 chr 4	NC_000004.12:g.99150767A>G
GRCh37.p13 chr 4	NC_000004.11:g.100071924A>G

Molecule type	Change	Amino acid[Codon]	SO Term
LOC100507053 transcript	NR_037884.1:n.	N/A	Intron Variant

Study	Population	Group	Sample #	Ref Allele	Alt Allele
1000Genomes	African	Sub	1322	A=0.775	G=0.225
1000Genomes	American	Sub	694	A=0.970	G=0.030
1000Genomes	East Asian	Sub	1008	A=1.000	G=0.000
1000Genomes	Europe	Sub	1006	A=0.999	G=0.001
1000Genomes	Global	Study-wide	5008	A=0.937	G=0.063
1000Genomes	South Asian	Sub	978	A=1.000	G=0.000
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	A=0.999	G=0.001
The Genome Aggregation Database	African	Sub	8724	A=0.786	G=0.214
The Genome Aggregation Database	American	Sub	838	A=0.990	G=0.010
The Genome Aggregation Database	East Asian	Sub	1622	A=1.000	G=0.000
The Genome Aggregation Database	Europe	Sub	18504	A=0.999	G=0.000
The Genome Aggregation Database	Global	Study-wide	29990	A=0.937	G=0.063
The Genome Aggregation Database	Other	Sub	302	A=1.000	G=0.000
Trans-Omics for Precision Medicine	Global	Study-wide	29118	A=0.897	G=0.103
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	A=0.999	G=0.001

PMID	Title	Author	Journal
24166409	Genome-wide association study of alcohol dependence:significant findings in African- and European-Americans including novel risk loci.	Gelernter J	Mol Psychiatry
24625756	Genetic determinants influencing human serum metabolome among African Americans.	Yu B	PLoS Genet

SNP ID	p-value	Traits	Study
rs17028615	1.00E-10	alcohol dependence	24166409
rs17028615	3.00E-08	alcohol dependence	24166409
rs17028615	6.00E-08	alcohol dependence	24166409

Position (v37)	eGene	GeneID	Variant	p-value	TSS	Tissue
There is no eQTL annotation for this SNP

Probe ID	Position	Gene	beta	p-value
There is no meQTL annotation for this SNP

rs17028615