SNP Detail Info-rs17029932

Organism: Homo sapiens

Alleles: G>A

Gene : Feature

None

p-value: Check p-value

Variation Type: SNV (Single Nucleotide Variation)

Frequency:

A=0038 (1141/29944,GnomAD)
A=0034 (989/29116,TOPMED)
A=0076 (380/5008,1000G)
A=0023 (89/3854,ALSPAC)
A=0022 (83/3708,TWINSUK)

Position: chr2:104542318 (GRCh38.p7) (2q12.1)

Phenotype: AD

Dataset:

GWASdb2

Publications: 1 publication(s)

Genomic View: See rs on genome

Enhancer: 32 Enhancers around

Promoter: 7 Promoters around

Sequence Name	Change(s)
GRCh38.p7 chr 2	NC_000002.12:g.104542318G>A
GRCh37.p13 chr 2	NC_000002.11:g.105158776G>A

Study	Population	Group	Sample #	Ref Allele	Alt Allele
1000Genomes	African	Sub	1322	G=0.949	A=0.051
1000Genomes	American	Sub	694	G=0.980	A=0.020
1000Genomes	East Asian	Sub	1008	G=0.729	A=0.271
1000Genomes	Europe	Sub	1006	G=0.981	A=0.019
1000Genomes	Global	Study-wide	5008	G=0.924	A=0.076
1000Genomes	South Asian	Sub	978	G=0.990	A=0.010
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	G=0.977	A=0.023
The Genome Aggregation Database	African	Sub	8720	G=0.960	A=0.040
The Genome Aggregation Database	American	Sub	838	G=0.970	A=0.030
The Genome Aggregation Database	East Asian	Sub	1620	G=0.730	A=0.270
The Genome Aggregation Database	Europe	Sub	18464	G=0.982	A=0.017
The Genome Aggregation Database	Global	Study-wide	29944	G=0.961	A=0.038
The Genome Aggregation Database	Other	Sub	302	G=1.000	A=0.000
Trans-Omics for Precision Medicine	Global	Study-wide	29116	G=0.966	A=0.034
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	G=0.978	A=0.022

PMID	Title	Author	Journal
21703634	A meta-analysis of two genome-wide association studies identifies 3 new loci for alcohol dependence.	Wang KS	J Psychiatr Res

SNP ID	p-value	Traits	Study
rs17029932	9.91E-05	alcohol dependence	21703634

Position (v37)	eGene	GeneID	Variant	p-value	TSS	Tissue
Chr2:105158776	FHL2	ENSG00000115641.14	G>A	3.9040e-3	-896194	Anterior_cingulate_cortex

Probe ID	Position	Gene	beta	p-value
There is no meQTL annotation for this SNP

Chromosome	Start	End	Region	Distance ( -/+ : Up/Downstream )
chr2	105117865	105118158	E068	-40618
chr2	105117865	105118158	E069	-40618
chr2	105163678	105164009	E069	4902
chr2	105117865	105118158	E070	-40618
chr2	105121230	105121378	E070	-37398
chr2	105121449	105121520	E070	-37256
chr2	105132968	105133312	E070	-25464
chr2	105154507	105155063	E070	-3713
chr2	105163678	105164009	E070	4902
chr2	105200326	105200433	E070	41550
chr2	105200474	105200650	E070	41698
chr2	105200761	105200811	E070	41985
chr2	105200980	105201105	E070	42204
chr2	105117865	105118158	E071	-40618
chr2	105121230	105121378	E071	-37398
chr2	105121449	105121520	E071	-37256
chr2	105163678	105164009	E071	4902
chr2	105121230	105121378	E072	-37398
chr2	105200761	105200811	E072	41985
chr2	105200980	105201105	E072	42204
chr2	105119773	105120278	E074	-38498
chr2	105121230	105121378	E074	-37398
chr2	105121449	105121520	E074	-37256
chr2	105134726	105135079	E074	-23697
chr2	105200326	105200433	E074	41550
chr2	105200474	105200650	E074	41698
chr2	105200761	105200811	E074	41985
chr2	105200980	105201105	E074	42204
chr2	105117865	105118158	E081	-40618
chr2	105119773	105120278	E081	-38498
chr2	105121230	105121378	E081	-37398
chr2	105200326	105200433	E082	41550

Chromosome	Start	End	Region	Distance(-/+:Up/Downstream)
chr2	105119349	105119742	E067	-39034
chr2	105119349	105119742	E068	-39034
chr2	105119349	105119742	E069	-39034
chr2	105119349	105119742	E070	-39034
chr2	105119349	105119742	E071	-39034
chr2	105119349	105119742	E072	-39034
chr2	105119349	105119742	E073	-39034

rs17029932