rs17031657

Homo sapiens
A>C
LOC101928114 : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
C=0154 (4629/29908,GnomAD)
C=0134 (3904/29118,TOPMED)
C=0172 (863/5008,1000G)
C=0180 (692/3854,ALSPAC)
C=0187 (692/3708,TWINSUK)
chr3:34405246 (GRCh38.p7) (3p22.3)
AD
GWASdb2
1   publication(s)
See rs on genome
21 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 3NC_000003.12:g.34405246A>C
GRCh37.p13 chr 3NC_000003.11:g.34446738A>C

Gene: LOC101928114, uncharacterized LOC101928114(plus strand)

Molecule type Change Amino acid[Codon] SO Term
LINC01811 transcript variant X1XR_001740635.1:n.N/AIntron Variant
LINC01811 transcript variant X2XR_001740636.1:n.N/AIntron Variant
LINC01811 transcript variant X4XR_001740638.1:n.N/AIntron Variant
LINC01811 transcript variant X5XR_001740639.1:n.N/AIntron Variant
LINC01811 transcript variant X6XR_001740640.1:n.N/AIntron Variant
LINC01811 transcript variant X7XR_001740641.1:n.N/AIntron Variant
LINC01811 transcript variant X3XR_001740637.1:n.N/AGenic Downstream Transcript Variant
LINC01811 transcript variant X10XR_001740642.1:n.N/AGenic Downstream Transcript Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322A=0.993C=0.007
1000GenomesAmericanSub694A=0.890C=0.110
1000GenomesEast AsianSub1008A=0.521C=0.479
1000GenomesEuropeSub1006A=0.823C=0.177
1000GenomesGlobalStudy-wide5008A=0.828C=0.172
1000GenomesSouth AsianSub978A=0.880C=0.120
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854A=0.820C=0.180
The Genome Aggregation DatabaseAfricanSub8726A=0.958C=0.042
The Genome Aggregation DatabaseAmericanSub834A=0.840C=0.160
The Genome Aggregation DatabaseEast AsianSub1578A=0.517C=0.483
The Genome Aggregation DatabaseEuropeSub18468A=0.820C=0.179
The Genome Aggregation DatabaseGlobalStudy-wide29908A=0.845C=0.154
The Genome Aggregation DatabaseOtherSub302A=0.830C=0.170
Trans-Omics for Precision MedicineGlobalStudy-wide29118A=0.865C=0.134
UK 10K study - TwinsTWIN COHORTStudy-wide3708A=0.813C=0.187
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs170316570.000755alcohol dependence20201924

eQTL of rs17031657 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs17031657 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr33442978634429890E070-16848
chr33442825034428362E081-18376
chr33442840034428457E081-18281
chr33442855634428735E081-18003
chr33442879734429761E081-16977
chr33442978634429890E081-16848
chr33443000534430134E081-16604
chr33443019334430796E081-15942
chr33443091734431072E081-15666
chr33444744834447630E081710
chr33444804534448099E0811307
chr33444846934448549E0811731
chr33444884434449015E0812106
chr33442825034428362E082-18376
chr33442840034428457E082-18281
chr33442855634428735E082-18003
chr33442879734429761E082-16977
chr33442978634429890E082-16848
chr33443000534430134E082-16604
chr33443019334430796E082-15942
chr33444846934448549E0821731