SNP Detail Info-rs17037473

Organism: Homo sapiens

Alleles: G>A

Gene : Feature

None

p-value: Check p-value

Variation Type: SNV (Single Nucleotide Variation)

Frequency:

A=0117 (3505/29866,GnomAD)
A=0173 (5054/29118,TOPMED)
A=0140 (703/5008,1000G)
A=0009 (34/3854,ALSPAC)
A=0011 (39/3708,TWINSUK)

Position: chr4:107173493 (GRCh38.p7) (4q25)

Phenotype: AD

Dataset:

GWASdb2

Publications: 1 publication(s)

Genomic View: See rs on genome

Enhancer: 0 Enhancer around

Promoter: 2 Promoters around

Sequence Name	Change(s)
GRCh38.p7 chr 4	NC_000004.12:g.107173493G>A
GRCh37.p13 chr 4	NC_000004.11:g.108094650G>A

Study	Population	Group	Sample #	Ref Allele	Alt Allele
1000Genomes	African	Sub	1322	G=0.594	A=0.406
1000Genomes	American	Sub	694	G=0.950	A=0.050
1000Genomes	East Asian	Sub	1008	G=0.930	A=0.070
1000Genomes	Europe	Sub	1006	G=0.993	A=0.007
1000Genomes	Global	Study-wide	5008	G=0.860	A=0.140
1000Genomes	South Asian	Sub	978	G=0.950	A=0.050
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	G=0.991	A=0.009
The Genome Aggregation Database	African	Sub	8656	G=0.635	A=0.365
The Genome Aggregation Database	American	Sub	838	G=0.960	A=0.040
The Genome Aggregation Database	East Asian	Sub	1582	G=0.916	A=0.084
The Genome Aggregation Database	Europe	Sub	18488	G=0.991	A=0.008
The Genome Aggregation Database	Global	Study-wide	29866	G=0.882	A=0.117
The Genome Aggregation Database	Other	Sub	302	G=0.940	A=0.060
Trans-Omics for Precision Medicine	Global	Study-wide	29118	G=0.826	A=0.173
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	G=0.989	A=0.011

PMID	Title	Author	Journal
24277619	ALDH2 is associated to alcohol dependence and is the major genetic determinant of "daily maximum drinks" in a GWAS study of an isolated rural Chinese sample.	Quillen EE	Am J Med Genet B Neuropsychiatr Genet

SNP ID	p-value	Traits	Study
rs17037473	0.000533	alcohol consumption (maxi-drinks)	24277619

Position (v37)	eGene	GeneID	Variant	p-value	TSS	Tissue
There is no eQTL annotation for this SNP

Probe ID	Position	Gene	beta	p-value
There is no meQTL annotation for this SNP

Chromosome	Start	End	Region	Distance(-/+:Up/Downstream)
chr4	108131744	108132529	E069	37094
chr4	108131744	108132529	E071	37094

rs17037473