rs17037483

Homo sapiens
A>C
None
Check p-value
SNV (Single Nucleotide Variation)
C=0119 (3561/29854,GnomAD)
C=0174 (5091/29118,TOPMED)
C=0141 (704/5008,1000G)
C=0009 (34/3854,ALSPAC)
C=0011 (39/3708,TWINSUK)
chr4:107178564 (GRCh38.p7) (4q25)
AD
GWASdb2
1   publication(s)
See rs on genome
0 Enhancer around
2 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 4NC_000004.12:g.107178564A>C
GRCh37.p13 chr 4NC_000004.11:g.108099721A>C

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322A=0.592C=0.408
1000GenomesAmericanSub694A=0.950C=0.050
1000GenomesEast AsianSub1008A=0.930C=0.070
1000GenomesEuropeSub1006A=0.993C=0.007
1000GenomesGlobalStudy-wide5008A=0.859C=0.141
1000GenomesSouth AsianSub978A=0.950C=0.050
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854A=0.991C=0.009
The Genome Aggregation DatabaseAfricanSub8720A=0.631C=0.369
The Genome Aggregation DatabaseAmericanSub836A=0.960C=0.040
The Genome Aggregation DatabaseEast AsianSub1564A=0.916C=0.084
The Genome Aggregation DatabaseEuropeSub18432A=0.991C=0.008
The Genome Aggregation DatabaseGlobalStudy-wide29854A=0.880C=0.119
The Genome Aggregation DatabaseOtherSub302A=0.940C=0.060
Trans-Omics for Precision MedicineGlobalStudy-wide29118A=0.825C=0.174
UK 10K study - TwinsTWIN COHORTStudy-wide3708A=0.989C=0.011
PMID Title Author Journal
24277619ALDH2 is associated to alcohol dependence and is the major genetic determinant of "daily maximum drinks" in a GWAS study of an isolated rural Chinese sample.Quillen EEAm J Med Genet B Neuropsychiatr Genet

P-Value

SNP ID p-value Traits Study
rs170374830.000533alcohol consumption (maxi-drinks)24277619

eQTL of rs17037483 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs17037483 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr4108131744108132529E06932023
chr4108131744108132529E07132023