rs17056140

Homo sapiens
T>C
None
Check p-value
SNV (Single Nucleotide Variation)
C=0076 (2298/29964,GnomAD)
C=0085 (2479/29118,TOPMED)
C=0060 (301/5008,1000G)
C=0055 (212/3854,ALSPAC)
C=0053 (195/3708,TWINSUK)
chr6:128630162 (GRCh38.p7) (6q22.33)
AD
GWASdb2
1   publication(s)
See rs on genome
4 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 6NC_000006.12:g.128630162T>C
GRCh37.p13 chr 6NC_000006.11:g.128951307T>C

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.878C=0.122
1000GenomesAmericanSub694T=0.940C=0.060
1000GenomesEast AsianSub1008T=1.000C=0.000
1000GenomesEuropeSub1006T=0.954C=0.046
1000GenomesGlobalStudy-wide5008T=0.940C=0.060
1000GenomesSouth AsianSub978T=0.950C=0.050
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.945C=0.055
The Genome Aggregation DatabaseAfricanSub8724T=0.866C=0.134
The Genome Aggregation DatabaseAmericanSub838T=0.950C=0.050
The Genome Aggregation DatabaseEast AsianSub1620T=1.000C=0.000
The Genome Aggregation DatabaseEuropeSub18482T=0.942C=0.057
The Genome Aggregation DatabaseGlobalStudy-wide29964T=0.923C=0.076
The Genome Aggregation DatabaseOtherSub300T=0.920C=0.080
Trans-Omics for Precision MedicineGlobalStudy-wide29118T=0.914C=0.085
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.947C=0.053
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs170561400.00069alcohol dependence20201924

eQTL of rs17056140 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs17056140 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr6128917462128917519E067-33788
chr6128917588128917689E067-33618
chr6128917742128917824E067-33483
chr6128993446128993553E06742139