rs17061146

Homo sapiens
C>T
None
Check p-value
SNV (Single Nucleotide Variation)
T=0126 (3689/29162,GnomAD)
T=0141 (4114/29118,TOPMED)
T=0138 (689/5008,1000G)
T=0047 (182/3854,ALSPAC)
T=0054 (202/3708,TWINSUK)
chr6:132292659 (GRCh38.p7) (6q23.2)
AD
GWASdb2
1   publication(s)
See rs on genome
9 Enhancers around
8 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 6NC_000006.12:g.132292659C>T
GRCh37.p13 chr 6NC_000006.11:g.132613798C>T

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.701T=0.299
1000GenomesAmericanSub694C=0.960T=0.040
1000GenomesEast AsianSub1008C=0.915T=0.085
1000GenomesEuropeSub1006C=0.940T=0.060
1000GenomesGlobalStudy-wide5008C=0.862T=0.138
1000GenomesSouth AsianSub978C=0.880T=0.120
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.953T=0.047
The Genome Aggregation DatabaseAfricanSub8574C=0.737T=0.263
The Genome Aggregation DatabaseAmericanSub728C=0.950T=0.050
The Genome Aggregation DatabaseEast AsianSub1584C=0.903T=0.097
The Genome Aggregation DatabaseEuropeSub17976C=0.931T=0.068
The Genome Aggregation DatabaseGlobalStudy-wide29162C=0.873T=0.126
The Genome Aggregation DatabaseOtherSub300C=0.960T=0.040
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.858T=0.141
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.946T=0.054
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs170611460.00072alcohol dependence20201924

eQTL of rs17061146 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs17061146 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr6132601237132601297E068-12501
chr6132619587132619737E0695789
chr6132618451132618501E0714653
chr6132601237132601297E072-12501
chr6132567323132568074E081-45724
chr6132598988132599144E081-14654
chr6132598988132599144E082-14654
chr6132610790132610905E082-2893
chr6132611046132611145E082-2653






Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr6132600698132601199E067-12599
chr6132600698132601199E068-12599
chr6132600698132601199E069-12599
chr6132600698132601199E070-12599
chr6132600698132601199E071-12599
chr6132600698132601199E072-12599
chr6132600698132601199E074-12599
chr6132600698132601199E082-12599