rs17064145

Homo sapiens
C>A
FLJ16171 : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
A=0188 (5639/29946,GnomAD)
A=0282 (8238/29118,TOPMED)
A=0216 (1083/5008,1000G)
A=0028 (107/3854,ALSPAC)
A=0031 (114/3708,TWINSUK)
chr5:174948706 (GRCh38.p7) (5q35.2)
AD
GWASdb2
1   publication(s)
See rs on genome
27 Enhancers around
12 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 5NC_000005.10:g.174948706C>A
GRCh37.p13 chr 5NC_000005.9:g.174375709C>A

Gene: FLJ16171, FLJ16171 protein(minus strand)

Molecule type Change Amino acid[Codon] SO Term
LINC01951 transcriptNR_046113.1:n.N/AIntron Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.328A=0.672
1000GenomesAmericanSub694C=0.890A=0.110
1000GenomesEast AsianSub1008C=0.969A=0.031
1000GenomesEuropeSub1006C=0.968A=0.032
1000GenomesGlobalStudy-wide5008C=0.784A=0.216
1000GenomesSouth AsianSub978C=0.940A=0.060
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.972A=0.028
The Genome Aggregation DatabaseAfricanSub8698C=0.422A=0.578
The Genome Aggregation DatabaseAmericanSub838C=0.920A=0.080
The Genome Aggregation DatabaseEast AsianSub1616C=0.970A=0.030
The Genome Aggregation DatabaseEuropeSub18492C=0.973A=0.026
The Genome Aggregation DatabaseGlobalStudy-wide29946C=0.811A=0.188
The Genome Aggregation DatabaseOtherSub302C=0.970A=0.030
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.717A=0.282
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.969A=0.031
PMID Title Author Journal
21703634A meta-analysis of two genome-wide association studies identifies 3 new loci for alcohol dependence.Wang KSJ Psychiatr Res

P-Value

SNP ID p-value Traits Study
rs170641458.04E-05alcohol dependence21703634

eQTL of rs17064145 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs17064145 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr5174352664174352902E067-22807
chr5174418976174419111E06743267
chr5174352664174352902E068-22807
chr5174362315174362414E068-13295
chr5174362732174363184E068-12525
chr5174418069174418178E06842360
chr5174418976174419111E06843267
chr5174362148174362286E069-13423
chr5174362315174362414E069-13295
chr5174362732174363184E069-12525
chr5174418069174418178E06942360
chr5174418976174419111E06943267
chr5174418976174419111E07043267
chr5174352664174352902E071-22807
chr5174362315174362414E071-13295
chr5174362732174363184E071-12525
chr5174418976174419111E07143267
chr5174362315174362414E072-13295
chr5174362732174363184E072-12525
chr5174418069174418178E07242360
chr5174362315174362414E073-13295
chr5174418069174418178E07342360
chr5174362315174362414E074-13295
chr5174362732174363184E074-12525
chr5174418069174418178E07442360
chr5174380517174380632E0814808
chr5174380794174381291E0815085









Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr5174337254174337719E067-37990
chr5174337790174337850E067-37859
chr5174337254174337719E068-37990
chr5174337254174337719E069-37990
chr5174337790174337850E069-37859
chr5174337254174337719E071-37990
chr5174337254174337719E072-37990
chr5174337790174337850E072-37859
chr5174337254174337719E073-37990
chr5174337790174337850E073-37859
chr5174337254174337719E074-37990
chr5174337790174337850E074-37859