rs17064176

Homo sapiens
G>A / G>T
DLGAP2 : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
T=0363 (10851/29894,GnomAD)
T=0337 (9821/29118,TOPMED)
T=0341 (1709/5008,1000G)
chr8:1652979 (GRCh38.p7) (8p23.3)
ND
GWASdb2
1   publication(s)
See rs on genome
22 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 8NC_000008.11:g.1652979G>A
GRCh38.p7 chr 8NC_000008.11:g.1652979G>T
GRCh37.p13 chr 8NC_000008.10:g.1601145G>A
GRCh37.p13 chr 8NC_000008.10:g.1601145G>T
DLGAP2 RefSeqGeneNG_009409.1:g.156577G>A
DLGAP2 RefSeqGeneNG_009409.1:g.156577G>T
GRCh38.p7 chr 8 alt locus HSCHR8_5_CTG1NT_187654.1:g.262262T>G
GRCh38.p7 chr 8 alt locus HSCHR8_5_CTG1NT_187654.1:g.262262T>A
GRCh38.p7 chr 8 alt locus HSCHR8_7_CTG1NT_187680.1:g.65868T>G
GRCh38.p7 chr 8 alt locus HSCHR8_7_CTG1NT_187680.1:g.65868T>A

Gene: DLGAP2, discs large homolog associated protein 2(plus strand)

Molecule type Change Amino acid[Codon] SO Term
DLGAP2 transcript variant 2NM_001277161.1:c.N/AIntron Variant
DLGAP2 transcript variant 1NM_004745.4:c.N/AIntron Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.633T=0.367
1000GenomesAmericanSub694G=0.620T=0.380
1000GenomesEast AsianSub1008G=0.643T=0.357
1000GenomesEuropeSub1006G=0.690T=0.310
1000GenomesGlobalStudy-wide5008G=0.659T=0.341
1000GenomesSouth AsianSub978G=0.710T=0.290
The Genome Aggregation DatabaseAfricanSub8688G=0.653T=0.347
The Genome Aggregation DatabaseAmericanSub838G=0.600T=0.400
The Genome Aggregation DatabaseEast AsianSub1614G=0.605T=0.395
The Genome Aggregation DatabaseEuropeSub18452G=0.633T=0.367
The Genome Aggregation DatabaseGlobalStudy-wide29894G=0.637T=0.363
The Genome Aggregation DatabaseOtherSub302G=0.700T=0.300
Trans-Omics for Precision MedicineGlobalStudy-wide29118G=0.662T=0.337
PMID Title Author Journal
20158304A genomewide association study of nicotine and alcohol dependence in Australian and Dutch populations.Lind PATwin Res Hum Genet

P-Value

SNP ID p-value Traits Study
rs170641762.01E-05alcohol and nictotine co-dependence20158304

eQTL of rs17064176 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs17064176 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr83607179936072096E068-6331
chr83602859036028807E070-49620
chr83602954536029599E070-48828
chr83607077536071014E070-7413
chr83608916936089209E07010742
chr83608923636089384E07010809
chr83608947736089849E07011050
chr83608985636089906E07011429
chr83609007336090166E07011646
chr83607179936072096E073-6331
chr83607215936072226E073-6201
chr83607228036072369E073-6058
chr83602859036028807E081-49620
chr83606886136068926E081-9501
chr83607077536071014E081-7413
chr83607106836071166E081-7261
chr83602859036028807E082-49620
chr83602954536029599E082-48828
chr83606973836070257E082-8170
chr83607179936072096E082-6331
chr83607215936072226E082-6201
chr83607228036072369E082-6058