rs170676

Homo sapiens
G>C
None
Check p-value
SNV (Single Nucleotide Variation)
G==0118 (3537/29948,GnomAD)
G==0099 (2909/29118,TOPMED)
G==0095 (474/5008,1000G)
G==0128 (495/3854,ALSPAC)
G==0140 (520/3708,TWINSUK)
chr21:20724023 (GRCh38.p7) (21q21.1)
AD
GWASdb2
1   publication(s)
See rs on genome
46 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 21NC_000021.9:g.20724023G>C
GRCh37.p13 chr 21NC_000021.8:g.22096341G>C

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.097C=0.903
1000GenomesAmericanSub694G=0.110C=0.890
1000GenomesEast AsianSub1008G=0.061C=0.939
1000GenomesEuropeSub1006G=0.130C=0.870
1000GenomesGlobalStudy-wide5008G=0.095C=0.905
1000GenomesSouth AsianSub978G=0.080C=0.920
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=0.128C=0.872
The Genome Aggregation DatabaseAfricanSub8722G=0.095C=0.905
The Genome Aggregation DatabaseAmericanSub836G=0.070C=0.930
The Genome Aggregation DatabaseEast AsianSub1620G=0.056C=0.944
The Genome Aggregation DatabaseEuropeSub18468G=0.136C=0.863
The Genome Aggregation DatabaseGlobalStudy-wide29948G=0.118C=0.881
The Genome Aggregation DatabaseOtherSub302G=0.090C=0.910
Trans-Omics for Precision MedicineGlobalStudy-wide29118G=0.099C=0.900
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.140C=0.860
PMID Title Author Journal
23743675A meta-analysis of two genome-wide association studies to identify novel loci for maximum number of alcoholic drinks.Kapoor MHum Genet

P-Value

SNP ID p-value Traits Study
rs1706767.5E-05alcohol consumption23743675

eQTL of rs170676 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs170676 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr212210684322106990E06710502
chr212210842522108506E06712084
chr212210926622109361E06712925
chr212210926622109361E06812925
chr212210941722109555E06813076
chr212210976622109877E06813425
chr212210991522110206E06813574
chr212210842522108506E06912084
chr212210864922108754E06912308
chr212210926622109361E06912925
chr212210941722109555E06913076
chr212207525122075412E070-20929
chr212207585422076066E070-20275
chr212210738722107450E07011046
chr212210773222107777E07011391
chr212210792222108038E07011581
chr212210926622109361E07012925
chr212210941722109555E07013076
chr212210976622109877E07013425
chr212210991522110206E07013574
chr212211230022112353E07015959
chr212210738722107450E07111046
chr212210773222107777E07111391
chr212210792222108038E07111581
chr212210842522108506E07112084
chr212210864922108754E07112308
chr212210926622109361E07112925
chr212210976622109877E07113425
chr212210991522110206E07113574
chr212210738722107450E07211046
chr212210773222107777E07211391
chr212210792222108038E07211581
chr212210842522108506E07212084
chr212210864922108754E07212308
chr212210661422106677E07410273
chr212210684322106990E07410502
chr212210738722107450E07411046
chr212210773222107777E07411391
chr212210792222108038E07411581
chr212210842522108506E07412084
chr212210864922108754E07412308
chr212210926622109361E07412925
chr212210991522110206E07413574
chr212210941722109555E08113076
chr212210976622109877E08113425
chr212210991522110206E08113574