rs17078124

Homo sapiens
C>T
None
Check p-value
SNV (Single Nucleotide Variation)
T=0159 (4758/29932,GnomAD)
T=0202 (5890/29118,TOPMED)
T=0184 (919/5008,1000G)
T=0115 (445/3854,ALSPAC)
T=0114 (422/3708,TWINSUK)
chr8:6779667 (GRCh38.p7) (8p23.1)
AD
GWASdb2
1   publication(s)
See rs on genome
148 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 8NC_000008.11:g.6779667C>T
GRCh37.p13 chr 8NC_000008.10:g.6637188C>T

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.690T=0.310
1000GenomesAmericanSub694C=0.890T=0.110
1000GenomesEast AsianSub1008C=0.795T=0.205
1000GenomesEuropeSub1006C=0.880T=0.120
1000GenomesGlobalStudy-wide5008C=0.816T=0.184
1000GenomesSouth AsianSub978C=0.890T=0.110
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.885T=0.115
The Genome Aggregation DatabaseAfricanSub8692C=0.705T=0.295
The Genome Aggregation DatabaseAmericanSub838C=0.890T=0.110
The Genome Aggregation DatabaseEast AsianSub1620C=0.820T=0.180
The Genome Aggregation DatabaseEuropeSub18480C=0.903T=0.096
The Genome Aggregation DatabaseGlobalStudy-wide29932C=0.841T=0.159
The Genome Aggregation DatabaseOtherSub302C=0.920T=0.080
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.797T=0.202
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.886T=0.114
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs170781240.000631alcohol dependence20201924

eQTL of rs17078124 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs17078124 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr865911596591295E067-45893
chr866021546602208E067-34980
chr866023376602502E067-34686
chr866025816602631E067-34557
chr866307976631081E067-6107
chr866311196631474E067-5714
chr866320616632111E067-5077
chr866321546632194E067-4994
chr866321956632300E067-4888
chr866325886632650E067-4538
chr866326786632807E067-4381
chr865900786590258E068-46930
chr865902836590344E068-46844
chr865903556590577E068-46611
chr865906936591135E068-46053
chr865911596591295E068-45893
chr865939536594929E068-42259
chr866018176601934E068-35254
chr866032616603388E068-33800
chr866332216633413E068-3775
chr866334806633811E068-3377
chr866338776633957E068-3231
chr866451976645852E0688009
chr866579706659071E06820782
chr865900786590258E069-46930
chr865902836590344E069-46844
chr865903556590577E069-46611
chr865906936591135E069-46053
chr865911596591295E069-45893
chr866021546602208E069-34980
chr866023376602502E069-34686
chr866325886632650E069-4538
chr866326786632807E069-4381
chr866330056633106E069-4082
chr866332216633413E069-3775
chr866334806633811E069-3377
chr866451976645852E0698009
chr866459586646009E0698770
chr866510876651154E06913899
chr865903556590577E070-46611
chr865906936591135E070-46053
chr866073716607949E070-29239
chr866451976645852E0708009
chr866500716650131E07012883
chr866501336650183E07012945
chr866504016650495E07013213
chr866505116650847E07013323
chr865892916589699E071-47489
chr865898036589925E071-47263
chr865906936591135E071-46053
chr865911596591295E071-45893
chr866018176601934E071-35254
chr866021546602208E071-34980
chr866023376602502E071-34686
chr866032616603388E071-33800
chr866311196631474E071-5714
chr866314766631855E071-5333
chr866318566632013E071-5175
chr866320616632111E071-5077
chr866321546632194E071-4994
chr866321956632300E071-4888
chr866330056633106E071-4082
chr866332216633413E071-3775
chr866334806633811E071-3377
chr866367466637848E0710
chr866451976645852E0718009
chr866516436651683E07114455
chr866517336651787E07114545
chr866520616652245E07114873
chr865873576587558E072-49630
chr865903556590577E072-46611
chr866073716607949E072-29239
chr866210056621302E072-15886
chr866314766631855E072-5333
chr866330056633106E072-4082
chr866332216633413E072-3775
chr866334806633811E072-3377
chr866451976645852E0728009
chr866579706659071E07220782
chr865906936591135E073-46053
chr865911596591295E073-45893
chr866018176601934E073-35254
chr866021546602208E073-34980
chr866023376602502E073-34686
chr866073716607949E073-29239
chr866318566632013E073-5175
chr866320616632111E073-5077
chr866321546632194E073-4994
chr866321956632300E073-4888
chr866451976645852E0738009
chr866510876651154E07313899
chr866516436651683E07314455
chr866517336651787E07314545
chr866520616652245E07314873
chr866523736652474E07315185
chr865892916589699E074-47489
chr865898036589925E074-47263
chr865900786590258E074-46930
chr865902836590344E074-46844
chr865903556590577E074-46611
chr865906936591135E074-46053
chr865911596591295E074-45893
chr865939536594929E074-42259
chr866006406600712E074-36476
chr866007356600819E074-36369
chr866008276600923E074-36265
chr866018176601934E074-35254
chr866021546602208E074-34980
chr866032616603388E074-33800
chr866045036604570E074-32618
chr866046396604689E074-32499
chr866047666604926E074-32262
chr866314766631855E074-5333
chr866318566632013E074-5175
chr866320616632111E074-5077
chr866321546632194E074-4994
chr866321956632300E074-4888
chr866325886632650E074-4538
chr866326786632807E074-4381
chr866332216633413E074-3775
chr866334806633811E074-3377
chr866338776633957E074-3231
chr866442316644328E0817043
chr866443846644424E0817196
chr866444966644563E0817308
chr866449356644985E0817747
chr866451976645852E0818009
chr866459586646009E0818770
chr866504016650495E08113213
chr866505116650847E08113323
chr866579706659071E08120782
chr866745106674581E08137322
chr866747386674785E08137550
chr866748186674910E08137630
chr866749766675026E08137788
chr866753326675513E08138144
chr865906936591135E082-46053
chr866318566632013E082-5175
chr866320616632111E082-5077
chr866321546632194E082-4994
chr866321956632300E082-4888
chr866442316644328E0827043
chr866443846644424E0827196
chr866444966644563E0827308
chr866745106674581E08237322
chr866747386674785E08237550
chr866748186674910E08237630
chr866749766675026E08237788