rs17085505

Homo sapiens
A>C / A>T
None
Check p-value
SNV (Single Nucleotide Variation)
C=0042 (1273/29976,GnomAD)
C=0042 (208/5008,1000G)
C=0020 (76/3854,ALSPAC)
C=0018 (68/3708,TWINSUK)
chr18:72076229 (GRCh38.p7) (18q22.3)
ND
GWASdb2
1   publication(s)
See rs on genome
46 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 18NC_000018.10:g.72076229A>C
GRCh38.p7 chr 18NC_000018.10:g.72076229A>T
GRCh37.p13 chr 18NC_000018.9:g.69743464A>C
GRCh37.p13 chr 18NC_000018.9:g.69743464A>T

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322A=0.909C=0.091
1000GenomesAmericanSub694A=0.950C=0.050
1000GenomesEast AsianSub1008A=0.969C=0.031
1000GenomesEuropeSub1006A=0.983C=0.017
1000GenomesGlobalStudy-wide5008A=0.958C=0.042
1000GenomesSouth AsianSub978A=1.000C=0.000
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854A=0.980C=0.020
The Genome Aggregation DatabaseAfricanSub8724A=0.918T=0.000
The Genome Aggregation DatabaseAmericanSub838A=0.940T=0.00,
The Genome Aggregation DatabaseEast AsianSub1614A=0.973T=0.000
The Genome Aggregation DatabaseEuropeSub18498A=0.974T=0.000
The Genome Aggregation DatabaseGlobalStudy-wide29976A=0.957T=0.000
The Genome Aggregation DatabaseOtherSub302A=1.000T=0.00,
UK 10K study - TwinsTWIN COHORTStudy-wide3708A=0.982C=0.018
PMID Title Author Journal
20158304A genomewide association study of nicotine and alcohol dependence in Australian and Dutch populations.Lind PATwin Res Hum Genet

P-Value

SNP ID p-value Traits Study
rs170855052.18E-06alcohol and nictotine co-dependence20158304

eQTL of rs17085505 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs17085505 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr184764068547640807E069-30400
chr184764088547640935E069-30272
chr184764095647641044E069-30163
chr184764106547641147E069-30060
chr184764117547641231E069-29976
chr184764437547644466E069-26741
chr184764449547644588E069-26619
chr184764473547644788E069-26419
chr184764148447641573E071-29634
chr184764437547644466E071-26741
chr184764449547644588E071-26619
chr184764473547644788E071-26419
chr184762619647626978E081-44229
chr184769399347694053E08122786
chr184769442047694628E08123213
chr184769481847694872E08123611
chr184770131847701378E08130111
chr184770384847704005E08132641
chr184770409847704180E08132891
chr184770418847704238E08132981
chr184770455147704601E08133344
chr184770483647704918E08133629
chr184770495347705301E08133746
chr184770561347705959E08134406
chr184770783747707891E08136630
chr184770813047708216E08136923
chr184770844747708564E08137240
chr184770858547708781E08137378
chr184770885947709323E08137652
chr184770985447710358E08138647
chr184771036547710601E08139158
chr184765194847652038E082-19169
chr184765234647652386E082-18821
chr184765295947653248E082-17959
chr184765467747656061E082-15146
chr184769442047694628E08223213
chr184769481847694872E08223611
chr184770455147704601E08233344
chr184770483647704918E08233629
chr184770699147707059E08235784
chr184770783747707891E08236630
chr184770813047708216E08236923
chr184770844747708564E08237240
chr184770858547708781E08237378
chr184770885947709323E08237652
chr184771282947713111E08241622