rs17086213

Homo sapiens
T>C
FLT3 : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
C=0272 (8157/29912,GnomAD)
C=0267 (7790/29116,TOPMED)
C=0253 (1267/5008,1000G)
C=0270 (1040/3854,ALSPAC)
C=0266 (988/3708,TWINSUK)
chr13:28010607 (GRCh38.p7) (13q12.2)
AD
GWASdb2
1   publication(s)
See rs on genome
5 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 13NC_000013.11:g.28010607T>C
GRCh37.p13 chr 13NC_000013.10:g.28584744T>C
FLT3 RefSeqGene LRG_457

Gene: FLT3, fms related tyrosine kinase 3(minus strand)

Molecule type Change Amino acid[Codon] SO Term
FLT3 transcript variant 1NM_004119.2:c.N/AIntron Variant
FLT3 transcript variant 2NR_130706.1:n.N/AIntron Variant
FLT3 transcript variant X1XM_011535015.2:c.N/AIntron Variant
FLT3 transcript variant X4XM_011535017.2:c.N/AIntron Variant
FLT3 transcript variant X5XM_011535018.2:c.N/AIntron Variant
FLT3 transcript variant X2XM_017020486.1:c.N/AIntron Variant
FLT3 transcript variant X3XM_017020487.1:c.N/AIntron Variant
FLT3 transcript variant X6XM_017020488.1:c.N/AIntron Variant
FLT3 transcript variant X7XM_017020489.1:c.N/AIntron Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.709C=0.291
1000GenomesAmericanSub694T=0.760C=0.240
1000GenomesEast AsianSub1008T=0.774C=0.226
1000GenomesEuropeSub1006T=0.712C=0.288
1000GenomesGlobalStudy-wide5008T=0.747C=0.253
1000GenomesSouth AsianSub978T=0.800C=0.200
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.730C=0.270
The Genome Aggregation DatabaseAfricanSub8692T=0.726C=0.274
The Genome Aggregation DatabaseAmericanSub838T=0.760C=0.240
The Genome Aggregation DatabaseEast AsianSub1612T=0.781C=0.219
The Genome Aggregation DatabaseEuropeSub18468T=0.721C=0.278
The Genome Aggregation DatabaseGlobalStudy-wide29912T=0.727C=0.272
The Genome Aggregation DatabaseOtherSub302T=0.730C=0.270
Trans-Omics for Precision MedicineGlobalStudy-wide29116T=0.732C=0.267
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.734C=0.266
PMID Title Author Journal
21314694Genomewide association analysis of symptoms of alcohol dependence in the molecular genetics of schizophrenia (MGS2) control sample.Kendler KSAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs170862130.000906alcohol dependence21314694

eQTL of rs17086213 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs17086213 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr132859682628596943E07112082
chr132859682628596943E07312082
chr132859694628597857E07312202
chr132860118428601655E08116440
chr132860179828601890E08117054