rs17086945

Homo sapiens
T>C
None
Check p-value
SNV (Single Nucleotide Variation)
C=0102 (2988/29132,GnomAD)
C=0147 (4299/29116,TOPMED)
C=0122 (611/5008,1000G)
C=0046 (177/3854,ALSPAC)
C=0051 (188/3708,TWINSUK)
chr13:70373933 (GRCh38.p7) (13q21.33)
AD
GWASdb2
1   publication(s)
See rs on genome
3 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 13NC_000013.11:g.70373933T>C
GRCh37.p13 chr 13NC_000013.10:g.70948065T>C
GRCh38.p7 chr 13 alt locus HSCHR13_1_CTG6NT_187597.1:g.34873T>C

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.730C=0.270
1000GenomesAmericanSub694T=0.880C=0.120
1000GenomesEast AsianSub1008T=0.998C=0.002
1000GenomesEuropeSub1006T=0.938C=0.062
1000GenomesGlobalStudy-wide5008T=0.878C=0.122
1000GenomesSouth AsianSub978T=0.890C=0.110
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.954C=0.046
The Genome Aggregation DatabaseAfricanSub8570T=0.761C=0.239
The Genome Aggregation DatabaseAmericanSub698T=0.840C=0.160
The Genome Aggregation DatabaseEast AsianSub1618T=1.000C=0.000
The Genome Aggregation DatabaseEuropeSub17944T=0.956C=0.044
The Genome Aggregation DatabaseGlobalStudy-wide29132T=0.897C=0.102
The Genome Aggregation DatabaseOtherSub302T=0.850C=0.150
Trans-Omics for Precision MedicineGlobalStudy-wide29116T=0.852C=0.147
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.949C=0.051
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs170869450.00013alcohol dependence(early age of onset)20201924
rs170869450.00066alcohol dependence20201924

eQTL of rs17086945 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs17086945 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr137094995370950331E0701888
chr137093767670937855E081-10210
chr137093802270938695E081-9370