rs17097654

Homo sapiens
G>T
LOC107986454 : Non Coding Transcript Variant
Check p-value
SNV (Single Nucleotide Variation)
T=0184 (5529/29956,GnomAD)
T=0203 (5912/29118,TOPMED)
T=0164 (820/5008,1000G)
T=0152 (586/3854,ALSPAC)
T=0153 (568/3708,TWINSUK)
chr5:141808749 (GRCh38.p7) (5q31.3)
ND
GWASdb2
1   publication(s)
See rs on genome
9 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 5NC_000005.10:g.141808749G>T
GRCh37.p13 chr 5NC_000005.9:g.141188315G>T

Gene: LOC107986454, uncharacterized LOC107986454(minus strand)

Molecule type Change Amino acid[Codon] SO Term
LOC107986454 transcriptXR_001742906.1:n....XR_001742906.1:n.8297C>AC>ANon Coding Transcript Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.679T=0.321
1000GenomesAmericanSub694G=0.870T=0.130
1000GenomesEast AsianSub1008G=0.918T=0.082
1000GenomesEuropeSub1006G=0.861T=0.139
1000GenomesGlobalStudy-wide5008G=0.836T=0.164
1000GenomesSouth AsianSub978G=0.910T=0.090
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=0.848T=0.152
The Genome Aggregation DatabaseAfricanSub8718G=0.712T=0.288
The Genome Aggregation DatabaseAmericanSub836G=0.890T=0.110
The Genome Aggregation DatabaseEast AsianSub1622G=0.919T=0.081
The Genome Aggregation DatabaseEuropeSub18478G=0.852T=0.148
The Genome Aggregation DatabaseGlobalStudy-wide29956G=0.815T=0.184
The Genome Aggregation DatabaseOtherSub302G=0.820T=0.180
Trans-Omics for Precision MedicineGlobalStudy-wide29118G=0.797T=0.203
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.847T=0.153
PMID Title Author Journal
20158304A genomewide association study of nicotine and alcohol dependence in Australian and Dutch populations.Lind PATwin Res Hum Genet

P-Value

SNP ID p-value Traits Study
rs170976541.27E-05alcohol and nictotine co-dependence20158304

eQTL of rs17097654 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs17097654 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr5141141754141141810E067-46505
chr5141141869141142077E067-46238
chr5141143021141143499E067-44816
chr5141150754141150846E067-37469
chr5141151052141151109E067-37206
chr5141153696141153746E067-34569
chr5141153834141154259E067-34056
chr5141162811141162921E067-25394
chr5141163030141163507E067-24808
chr5141189593141189653E0671278
chr5141190575141191717E0672260
chr5141192025141192179E0673710
chr5141193505141193618E0675190
chr5141193705141193887E0675390
chr5141194304141194427E0675989
chr5141194653141194713E0676338
chr5141195884141196973E0677569
chr5141197056141197152E0678741
chr5141197210141197569E0678895
chr5141200929141201491E06712614
chr5141201800141201975E06713485
chr5141202055141202135E06713740
chr5141202726141202825E06714411
chr5141205340141205384E06717025
chr5141205442141205602E06717127
chr5141205642141205988E06717327
chr5141206408141206496E06718093
chr5141206928141206993E06718613
chr5141214042141214164E06725727
chr5141215219141215297E06726904
chr5141215383141215433E06727068
chr5141215528141216275E06727213
chr5141216303141216497E06727988
chr5141216562141216624E06728247
chr5141217926141218372E06729611
chr5141218519141219103E06730204
chr5141221158141221684E06732843
chr5141222013141222280E06733698
chr5141222333141223394E06734018
chr5141224914141225459E06736599
chr5141225641141225925E06737326
chr5141225930141226134E06737615
chr5141230361141230838E06742046
chr5141230905141231044E06742590
chr5141234818141234942E06746503
chr5141235000141235050E06746685
chr5141235295141235664E06746980
chr5141236715141236762E06748400
chr5141237100141237150E06748785
chr5141237551141238302E06749236
chr5141141629141141679E068-46636
chr5141141754141141810E068-46505
chr5141141869141142077E068-46238
chr5141150754141150846E068-37469
chr5141151052141151109E068-37206
chr5141151538141151605E068-36710
chr5141151797141151847E068-36468
chr5141152008141152164E068-36151
chr5141160734141160847E068-27468
chr5141161073141161223E068-27092
chr5141163539141163847E068-24468
chr5141164080141164236E068-24079
chr5141183541141183781E068-4534
chr5141188296141188346E0680
chr5141189196141189272E068881
chr5141189593141189653E0681278
chr5141190575141191717E0682260
chr5141192247141192368E0683932
chr5141193505141193618E0685190
chr5141193705141193887E0685390
chr5141194304141194427E0685989
chr5141194653141194713E0686338
chr5141194937141195252E0686622
chr5141195884141196973E0687569
chr5141197056141197152E0688741
chr5141197210141197569E0688895
chr5141200929141201491E06812614
chr5141201800141201975E06813485
chr5141202055141202135E06813740
chr5141202726141202825E06814411
chr5141204172141204222E06815857
chr5141204783141204980E06816468
chr5141204989141205238E06816674
chr5141205340141205384E06817025
chr5141205442141205602E06817127
chr5141205642141205988E06817327
chr5141206408141206496E06818093
chr5141206928141206993E06818613
chr5141215219141215297E06826904
chr5141215383141215433E06827068
chr5141215528141216275E06827213
chr5141216303141216497E06827988
chr5141216562141216624E06828247
chr5141217926141218372E06829611
chr5141218519141219103E06830204
chr5141221018141221141E06832703
chr5141221158141221684E06832843
chr5141222013141222280E06833698
chr5141224780141224899E06836465
chr5141224914141225459E06836599
chr5141230361141230838E06842046
chr5141230905141231044E06842590
chr5141234818141234942E06846503
chr5141141629141141679E069-46636
chr5141141754141141810E069-46505
chr5141141869141142077E069-46238
chr5141143021141143499E069-44816
chr5141143640141143690E069-44625
chr5141143764141143935E069-44380
chr5141150754141150846E069-37469
chr5141151052141151109E069-37206
chr5141151538141151605E069-36710
chr5141151797141151847E069-36468
chr5141163030141163507E069-24808
chr5141163539141163847E069-24468
chr5141167368141167418E069-20897
chr5141167923141168160E069-20155
chr5141188296141188346E0690
chr5141188743141188856E069428
chr5141189196141189272E069881
chr5141189593141189653E0691278
chr5141192025141192179E0693710
chr5141192247141192368E0693932
chr5141193505141193618E0695190
chr5141193705141193887E0695390
chr5141194304141194427E0695989
chr5141194653141194713E0696338
chr5141194937141195252E0696622
chr5141195884141196973E0697569
chr5141197056141197152E0698741
chr5141201800141201975E06913485
chr5141202055141202135E06913740
chr5141202726141202825E06914411
chr5141203453141203542E06915138
chr5141203813141203868E06915498
chr5141204172141204222E06915857
chr5141204783141204980E06916468
chr5141204989141205238E06916674
chr5141205340141205384E06917025
chr5141205442141205602E06917127
chr5141205642141205988E06917327
chr5141206408141206496E06918093
chr5141215219141215297E06926904
chr5141215383141215433E06927068
chr5141215528141216275E06927213
chr5141216303141216497E06927988
chr5141216562141216624E06928247
chr5141217926141218372E06929611
chr5141218519141219103E06930204
chr5141219715141219849E06931400
chr5141220011141220154E06931696
chr5141221018141221141E06932703
chr5141221158141221684E06932843
chr5141222013141222280E06933698
chr5141222333141223394E06934018
chr5141223564141223623E06935249
chr5141224557141224607E06936242
chr5141224780141224899E06936465
chr5141224914141225459E06936599
chr5141225641141225925E06937326
chr5141225930141226134E06937615
chr5141227377141227447E06939062
chr5141227507141227599E06939192
chr5141227639141227679E06939324
chr5141230361141230838E06942046
chr5141230905141231044E06942590
chr5141231128141231212E06942813
chr5141231249141231373E06942934
chr5141231698141231803E06943383
chr5141233169141233692E06944854
chr5141233917141234157E06945602
chr5141234818141234942E06946503
chr5141235000141235050E06946685
chr5141235295141235664E06946980
chr5141236715141236762E06948400
chr5141237100141237150E06948785
chr5141141754141141810E070-46505
chr5141141869141142077E070-46238
chr5141142492141142630E070-45685
chr5141143021141143499E070-44816
chr5141143640141143690E070-44625
chr5141143764141143935E070-44380
chr5141145595141145732E070-42583
chr5141150754141150846E070-37469
chr5141151052141151109E070-37206
chr5141151538141151605E070-36710
chr5141151797141151847E070-36468
chr5141153513141153677E070-34638
chr5141153696141153746E070-34569
chr5141153834141154259E070-34056
chr5141159031141159536E070-28779
chr5141160734141160847E070-27468
chr5141161073141161223E070-27092
chr5141163030141163507E070-24808
chr5141163539141163847E070-24468
chr5141168297141168376E070-19939
chr5141176358141176606E070-11709
chr5141176898141177311E070-11004
chr5141185482141185964E070-2351
chr5141192025141192179E0703710
chr5141192247141192368E0703932
chr5141193705141193887E0705390
chr5141194304141194427E0705989
chr5141195884141196973E0707569
chr5141200929141201491E07012614
chr5141201800141201975E07013485
chr5141202055141202135E07013740
chr5141202726141202825E07014411
chr5141204989141205238E07016674
chr5141205340141205384E07017025
chr5141205442141205602E07017127
chr5141205642141205988E07017327
chr5141217926141218372E07029611
chr5141219715141219849E07031400
chr5141220011141220154E07031696
chr5141220287141220614E07031972
chr5141220677141220744E07032362
chr5141220797141220939E07032482
chr5141221018141221141E07032703
chr5141221158141221684E07032843
chr5141222013141222280E07033698
chr5141222333141223394E07034018
chr5141223564141223623E07035249
chr5141223990141224227E07035675
chr5141224557141224607E07036242
chr5141224780141224899E07036465
chr5141226919141227089E07038604
chr5141227377141227447E07039062
chr5141227507141227599E07039192
chr5141227639141227679E07039324
chr5141230905141231044E07042590
chr5141231128141231212E07042813
chr5141235000141235050E07046685
chr5141235295141235664E07046980
chr5141141629141141679E071-46636
chr5141141754141141810E071-46505
chr5141141869141142077E071-46238
chr5141145595141145732E071-42583
chr5141151052141151109E071-37206
chr5141151538141151605E071-36710
chr5141160734141160847E071-27468
chr5141185289141185409E071-2906
chr5141185482141185964E071-2351
chr5141189196141189272E071881
chr5141189593141189653E0711278
chr5141190575141191717E0712260
chr5141192025141192179E0713710
chr5141192247141192368E0713932
chr5141193505141193618E0715190
chr5141193705141193887E0715390
chr5141194304141194427E0715989
chr5141194653141194713E0716338
chr5141194937141195252E0716622
chr5141195884141196973E0717569
chr5141197056141197152E0718741
chr5141197210141197569E0718895
chr5141200929141201491E07112614
chr5141202055141202135E07113740
chr5141202726141202825E07114411
chr5141203813141203868E07115498
chr5141204172141204222E07115857
chr5141204783141204980E07116468
chr5141204989141205238E07116674
chr5141205340141205384E07117025
chr5141205442141205602E07117127
chr5141205642141205988E07117327
chr5141206408141206496E07118093
chr5141206928141206993E07118613
chr5141215219141215297E07126904
chr5141215383141215433E07127068
chr5141215528141216275E07127213
chr5141216303141216497E07127988
chr5141216562141216624E07128247
chr5141216688141216818E07128373
chr5141217926141218372E07129611
chr5141218519141219103E07130204
chr5141219715141219849E07131400
chr5141220011141220154E07131696
chr5141220287141220614E07131972
chr5141220677141220744E07132362
chr5141220797141220939E07132482
chr5141221018141221141E07132703
chr5141221158141221684E07132843
chr5141222013141222280E07133698
chr5141222333141223394E07134018
chr5141224557141224607E07136242
chr5141224780141224899E07136465
chr5141224914141225459E07136599
chr5141225641141225925E07137326
chr5141225930141226134E07137615
chr5141230361141230838E07142046
chr5141230905141231044E07142590
chr5141231128141231212E07142813
chr5141234818141234942E07146503
chr5141235000141235050E07146685
chr5141235295141235664E07146980
chr5141237551141238302E07149236
chr5141141629141141679E072-46636
chr5141141754141141810E072-46505
chr5141141869141142077E072-46238
chr5141142492141142630E072-45685
chr5141143021141143499E072-44816
chr5141150754141150846E072-37469
chr5141151052141151109E072-37206
chr5141153834141154259E072-34056
chr5141163030141163507E072-24808
chr5141163539141163847E072-24468
chr5141167923141168160E072-20155
chr5141168297141168376E072-19939
chr5141184261141184465E072-3850
chr5141192025141192179E0723710
chr5141193312141193447E0724997
chr5141193505141193618E0725190
chr5141193705141193887E0725390
chr5141194304141194427E0725989
chr5141194653141194713E0726338
chr5141194937141195252E0726622
chr5141195884141196973E0727569
chr5141197056141197152E0728741
chr5141200929141201491E07212614
chr5141201800141201975E07213485
chr5141202055141202135E07213740
chr5141205340141205384E07217025
chr5141205442141205602E07217127
chr5141205642141205988E07217327
chr5141206408141206496E07218093
chr5141206928141206993E07218613
chr5141215219141215297E07226904
chr5141215383141215433E07227068
chr5141215528141216275E07227213
chr5141216303141216497E07227988
chr5141216562141216624E07228247
chr5141217926141218372E07229611
chr5141218519141219103E07230204
chr5141219424141219645E07231109
chr5141220797141220939E07232482
chr5141221018141221141E07232703
chr5141221158141221684E07232843
chr5141222013141222280E07233698
chr5141222333141223394E07234018
chr5141223564141223623E07235249
chr5141223990141224227E07235675
chr5141224557141224607E07236242
chr5141224780141224899E07236465
chr5141224914141225459E07236599
chr5141225641141225925E07237326
chr5141225930141226134E07237615
chr5141233169141233692E07244854
chr5141233917141234157E07245602
chr5141234818141234942E07246503
chr5141235000141235050E07246685
chr5141235295141235664E07246980
chr5141236715141236762E07248400
chr5141237100141237150E07248785
chr5141237551141238302E07249236
chr5141141754141141810E073-46505
chr5141141869141142077E073-46238
chr5141142492141142630E073-45685
chr5141143021141143499E073-44816
chr5141143640141143690E073-44625
chr5141143764141143935E073-44380
chr5141144110141144175E073-44140
chr5141144312141144379E073-43936
chr5141145595141145732E073-42583
chr5141150754141150846E073-37469
chr5141151052141151109E073-37206
chr5141151538141151605E073-36710
chr5141151797141151847E073-36468
chr5141152008141152164E073-36151
chr5141157829141158146E073-30169
chr5141158557141158607E073-29708
chr5141158636141158686E073-29629
chr5141159031141159536E073-28779
chr5141160393141160453E073-27862
chr5141160734141160847E073-27468
chr5141161073141161223E073-27092
chr5141162811141162921E073-25394
chr5141163030141163507E073-24808
chr5141167368141167418E073-20897
chr5141167923141168160E073-20155
chr5141168297141168376E073-19939
chr5141183541141183781E073-4534
chr5141189593141189653E0731278
chr5141190575141191717E0732260
chr5141192025141192179E0733710
chr5141192247141192368E0733932
chr5141193312141193447E0734997
chr5141193505141193618E0735190
chr5141193705141193887E0735390
chr5141194304141194427E0735989
chr5141194653141194713E0736338
chr5141194937141195252E0736622
chr5141201800141201975E07313485
chr5141202055141202135E07313740
chr5141202726141202825E07314411
chr5141203453141203542E07315138
chr5141203813141203868E07315498
chr5141206408141206496E07318093
chr5141206928141206993E07318613
chr5141215219141215297E07326904
chr5141215383141215433E07327068
chr5141215528141216275E07327213
chr5141216303141216497E07327988
chr5141216562141216624E07328247
chr5141216688141216818E07328373
chr5141217926141218372E07329611
chr5141218519141219103E07330204
chr5141219424141219645E07331109
chr5141219715141219849E07331400
chr5141220011141220154E07331696
chr5141220287141220614E07331972
chr5141220677141220744E07332362
chr5141220797141220939E07332482
chr5141221018141221141E07332703
chr5141221158141221684E07332843
chr5141222013141222280E07333698
chr5141222333141223394E07334018
chr5141223564141223623E07335249
chr5141223990141224227E07335675
chr5141224557141224607E07336242
chr5141224914141225459E07336599
chr5141225641141225925E07337326
chr5141225930141226134E07337615
chr5141230905141231044E07342590
chr5141231128141231212E07342813
chr5141231249141231373E07342934
chr5141231698141231803E07343383
chr5141233917141234157E07345602
chr5141234818141234942E07346503
chr5141235000141235050E07346685
chr5141235295141235664E07346980
chr5141236715141236762E07348400
chr5141237100141237150E07348785
chr5141237551141238302E07349236
chr5141190575141191717E0742260
chr5141192025141192179E0743710
chr5141193505141193618E0745190
chr5141193705141193887E0745390
chr5141194304141194427E0745989
chr5141194653141194713E0746338
chr5141194937141195252E0746622
chr5141195884141196973E0747569
chr5141200929141201491E07412614
chr5141201800141201975E07413485
chr5141202055141202135E07413740
chr5141204172141204222E07415857
chr5141204783141204980E07416468
chr5141204989141205238E07416674
chr5141205340141205384E07417025
chr5141205442141205602E07417127
chr5141205642141205988E07417327
chr5141215219141215297E07426904
chr5141215383141215433E07427068
chr5141215528141216275E07427213
chr5141216303141216497E07427988
chr5141216562141216624E07428247
chr5141216688141216818E07428373
chr5141217926141218372E07429611
chr5141218519141219103E07430204
chr5141220797141220939E07432482
chr5141221018141221141E07432703
chr5141221158141221684E07432843
chr5141224557141224607E07436242
chr5141224780141224899E07436465
chr5141224914141225459E07436599
chr5141225641141225925E07437326
chr5141225930141226134E07437615
chr5141230361141230838E07442046
chr5141235000141235050E07446685
chr5141235295141235664E07446980
chr5141141629141141679E081-46636
chr5141141754141141810E081-46505
chr5141141869141142077E081-46238
chr5141142492141142630E081-45685
chr5141143021141143499E081-44816
chr5141143640141143690E081-44625
chr5141143764141143935E081-44380
chr5141144110141144175E081-44140
chr5141144312141144379E081-43936
chr5141150754141150846E081-37469
chr5141151052141151109E081-37206
chr5141151538141151605E081-36710
chr5141151797141151847E081-36468
chr5141152008141152164E081-36151
chr5141153513141153677E081-34638
chr5141153696141153746E081-34569
chr5141153834141154259E081-34056
chr5141157829141158146E081-30169
chr5141160393141160453E081-27862
chr5141160734141160847E081-27468
chr5141161073141161223E081-27092
chr5141162811141162921E081-25394
chr5141163030141163507E081-24808
chr5141163539141163847E081-24468
chr5141164080141164236E081-24079
chr5141167368141167418E081-20897
chr5141167923141168160E081-20155
chr5141172811141173152E081-15163
chr5141176358141176606E081-11709
chr5141176898141177311E081-11004
chr5141185482141185964E081-2351
chr5141186247141186531E081-1784
chr5141186649141186701E081-1614
chr5141187065141187115E081-1200
chr5141188743141188856E081428
chr5141189196141189272E081881
chr5141190575141191717E0812260
chr5141192025141192179E0813710
chr5141192247141192368E0813932
chr5141193705141193887E0815390
chr5141194304141194427E0815989
chr5141200929141201491E08112614
chr5141201800141201975E08113485
chr5141204172141204222E08115857
chr5141204783141204980E08116468
chr5141204989141205238E08116674
chr5141205340141205384E08117025
chr5141205442141205602E08117127
chr5141205642141205988E08117327
chr5141206408141206496E08118093
chr5141217926141218372E08129611
chr5141218519141219103E08130204
chr5141220287141220614E08131972
chr5141220677141220744E08132362
chr5141220797141220939E08132482
chr5141221018141221141E08132703
chr5141221158141221684E08132843
chr5141222013141222280E08133698
chr5141222333141223394E08134018
chr5141223564141223623E08135249
chr5141223990141224227E08135675
chr5141224557141224607E08136242
chr5141224780141224899E08136465
chr5141224914141225459E08136599
chr5141225641141225925E08137326
chr5141225930141226134E08137615
chr5141226919141227089E08138604
chr5141230361141230838E08142046
chr5141230905141231044E08142590
chr5141231128141231212E08142813
chr5141231249141231373E08142934
chr5141235295141235664E08146980
chr5141141629141141679E082-46636
chr5141141754141141810E082-46505
chr5141141869141142077E082-46238
chr5141142492141142630E082-45685
chr5141143021141143499E082-44816
chr5141143640141143690E082-44625
chr5141143764141143935E082-44380
chr5141144110141144175E082-44140
chr5141150754141150846E082-37469
chr5141151052141151109E082-37206
chr5141151538141151605E082-36710
chr5141151797141151847E082-36468
chr5141152008141152164E082-36151
chr5141153513141153677E082-34638
chr5141153696141153746E082-34569
chr5141153834141154259E082-34056
chr5141160734141160847E082-27468
chr5141161073141161223E082-27092
chr5141162811141162921E082-25394
chr5141163030141163507E082-24808
chr5141163539141163847E082-24468
chr5141164080141164236E082-24079
chr5141167923141168160E082-20155
chr5141176898141177311E082-11004
chr5141186247141186531E082-1784
chr5141186649141186701E082-1614
chr5141190575141191717E0822260
chr5141192025141192179E0823710
chr5141192247141192368E0823932
chr5141194304141194427E0825989
chr5141200929141201491E08212614
chr5141201800141201975E08213485
chr5141202055141202135E08213740
chr5141204989141205238E08216674
chr5141205340141205384E08217025
chr5141205442141205602E08217127
chr5141205642141205988E08217327
chr5141217926141218372E08229611
chr5141220287141220614E08231972
chr5141220677141220744E08232362
chr5141220797141220939E08232482
chr5141221018141221141E08232703
chr5141221158141221684E08232843
chr5141222013141222280E08233698
chr5141223990141224227E08235675
chr5141224557141224607E08236242
chr5141224780141224899E08236465
chr5141224914141225459E08236599










Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr5141228034141230224E06739719
chr5141228034141230224E06839719
chr5141228034141230224E06939719
chr5141228034141230224E07039719
chr5141228034141230224E07139719
chr5141228034141230224E07239719
chr5141228034141230224E07339719
chr5141228034141230224E07439719
chr5141228034141230224E08239719