rs17115341

Homo sapiens
C>G / C>T
DAB1 : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
T=0095 (2871/29972,GnomAD)
T=0121 (608/5008,1000G)
T=0094 (361/3854,ALSPAC)
T=0092 (341/3708,TWINSUK)
chr1:57200259 (GRCh38.p7) (1p32.2)
AD
GWASdb2
1   publication(s)
See rs on genome
1 Enhancer around
23 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 1NC_000001.11:g.57200259C>G
GRCh38.p7 chr 1NC_000001.11:g.57200259C>T
GRCh37.p13 chr 1NC_000001.10:g.57665932C>G
GRCh37.p13 chr 1NC_000001.10:g.57665932C>T
DAB1 RefSeqGeneNG_046914.1:g.1055281G>C
DAB1 RefSeqGeneNG_046914.1:g.1055281G>A

Gene: DAB1, DAB1, reelin adaptor protein(minus strand)

Molecule type Change Amino acid[Codon] SO Term
DAB1 transcriptNM_021080.3:c.N/AIntron Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.937T=0.063
1000GenomesAmericanSub694C=0.710T=0.290
1000GenomesEast AsianSub1008C=0.845T=0.155
1000GenomesEuropeSub1006C=0.900T=0.100
1000GenomesGlobalStudy-wide5008C=0.879T=0.121
1000GenomesSouth AsianSub978C=0.930T=0.070
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.906T=0.094
The Genome Aggregation DatabaseAfricanSub8720C=0.951T=0.049
The Genome Aggregation DatabaseAmericanSub838C=0.730T=0.270
The Genome Aggregation DatabaseEast AsianSub1616C=0.824T=0.176
The Genome Aggregation DatabaseEuropeSub18496C=0.896T=0.103
The Genome Aggregation DatabaseGlobalStudy-wide29972C=0.904T=0.095
The Genome Aggregation DatabaseOtherSub302C=0.940T=0.060
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.908T=0.092
PMID Title Author Journal
21314694Genomewide association analysis of symptoms of alcohol dependence in the molecular genetics of schizophrenia (MGS2) control sample.Kendler KSAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs171153410.000739alcohol dependence21314694

eQTL of rs17115341 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs17115341 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr1149204365149204625E06949530

Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr1149193628149193713E06838793
chr1149194532149194716E06839697
chr1149155618149155933E069783
chr1149156042149156341E0691207
chr1149193874149194034E06939039
chr1149194082149194238E06939247
chr1149194532149194716E06939697
chr1149155618149155933E070783
chr1149156042149156341E0701207
chr1149156499149156781E0701664
chr1149194082149194238E07139247
chr1149194532149194716E07139697
chr1149155618149155933E072783
chr1149156042149156341E0721207
chr1149194532149194716E07239697
chr1149193874149194034E07339039
chr1149194082149194238E07339247
chr1149194532149194716E07339697
chr1149194532149194716E07439697
chr1149156499149156781E0811664
chr1149155618149155933E082783
chr1149156042149156341E0821207
chr1149156499149156781E0821664