rs17135017

Homo sapiens
G>A
None
Check p-value
SNV (Single Nucleotide Variation)
A=0229 (6852/29856,GnomAD)
A=0281 (8199/29118,TOPMED)
A=0201 (1006/5008,1000G)
A=0183 (706/3854,ALSPAC)
A=0183 (679/3708,TWINSUK)
chr10:3291338 (GRCh38.p7) (10p15.2)
AD
GWASdb2
1   publication(s)
See rs on genome
72 Enhancers around
9 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 10NC_000010.11:g.3291338G>A
GRCh37.p13 chr 10NC_000010.10:g.3333530G>A

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.566A=0.434
1000GenomesAmericanSub694G=0.840A=0.160
1000GenomesEast AsianSub1008G=0.958A=0.042
1000GenomesEuropeSub1006G=0.827A=0.173
1000GenomesGlobalStudy-wide5008G=0.799A=0.201
1000GenomesSouth AsianSub978G=0.890A=0.110
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=0.817A=0.183
The Genome Aggregation DatabaseAfricanSub8704G=0.595A=0.405
The Genome Aggregation DatabaseAmericanSub828G=0.860A=0.140
The Genome Aggregation DatabaseEast AsianSub1618G=0.954A=0.046
The Genome Aggregation DatabaseEuropeSub18404G=0.832A=0.167
The Genome Aggregation DatabaseGlobalStudy-wide29856G=0.770A=0.229
The Genome Aggregation DatabaseOtherSub302G=0.800A=0.200
Trans-Omics for Precision MedicineGlobalStudy-wide29118G=0.718A=0.281
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.817A=0.183
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs171350170.0000043alcohol dependence20201924
rs171350170.00000432alcoholismpha002892

eQTL of rs17135017 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs17135017 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr1033658763367357E06732346
chr1033727293373703E06839199
chr1032906563291770E069-41760
chr1033355763335637E0692046
chr1033356453335718E0692115
chr1033357463336169E0692216
chr1033362193336853E0692689
chr1033658763367357E06932346
chr1033119393312403E070-21127
chr1033124943312554E070-20976
chr1033658763367357E07032346
chr1033674623367591E07033932
chr1033727293373703E07039199
chr1033825823382664E07049052
chr1033355763335637E0712046
chr1033356453335718E0712115
chr1033357463336169E0712216
chr1033362193336853E0712689
chr1033372453337407E0713715
chr1033375543337648E0714024
chr1033657593365856E07132229
chr1033658763367357E07132346
chr1033657593365856E07232229
chr1033658763367357E07232346
chr1033657593365856E07332229
chr1033658763367357E07332346
chr1032851043285182E074-48348
chr1033658763367357E07432346
chr1033126453314040E081-19490
chr1033142813314378E081-19152
chr1033144553314517E081-19013
chr1033145773314782E081-18748
chr1033232303323405E081-10125
chr1033346833335542E0811153
chr1033355763335637E0812046
chr1033356453335718E0812115
chr1033357463336169E0812216
chr1033362193336853E0812689
chr1033369453337062E0813415
chr1033372453337407E0813715
chr1033375543337648E0814024
chr1033377423337960E0814212
chr1033471213347184E08113591
chr1033472603347594E08113730
chr1033478713347933E08114341
chr1033481243348674E08114594
chr1033487223348843E08115192
chr1033489123348963E08115382
chr1033526043353118E08119074
chr1033531593353210E08119629
chr1033547143355077E08121184
chr1033657593365856E08132229
chr1033658763367357E08132346
chr1033674623367591E08133932
chr1033682753368456E08134745
chr1033686193369443E08135089
chr1033727293373703E08139199
chr1033739213373997E08140391
chr1033346833335542E0821153
chr1033355763335637E0822046
chr1033356453335718E0822115
chr1033357463336169E0822216
chr1033362193336853E0822689
chr1033369453337062E0823415
chr1033377423337960E0824212
chr1033492763349395E08215746
chr1033526043353118E08219074
chr1033531593353210E08219629
chr1033657593365856E08232229
chr1033658763367357E08232346
chr1033674623367591E08233932
chr1033727293373703E08239199










Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr1033191623319212E067-14318
chr1033193213319371E067-14159
chr1033193963319446E067-14084
chr1033191623319212E072-14318
chr1033193213319371E072-14159
chr1033193963319446E072-14084
chr1033195373319659E072-13871
chr1033606963360991E07227166
chr1033611593361344E07227629