rs1714081

Homo sapiens
C>T
None
Check p-value
SNV (Single Nucleotide Variation)
C==0430 (12849/29876,GnomAD)
C==0467 (13608/29118,TOPMED)
C==0400 (2003/5008,1000G)
C==0442 (1702/3854,ALSPAC)
C==0453 (1678/3708,TWINSUK)
chr4:35936553 (GRCh38.p7) (4p14)
ND
GWASdb2
1   publication(s)
See rs on genome
6 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 4NC_000004.12:g.35936553C>T
GRCh37.p13 chr 4NC_000004.11:g.35938175C>T

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.533T=0.467
1000GenomesAmericanSub694C=0.410T=0.590
1000GenomesEast AsianSub1008C=0.211T=0.789
1000GenomesEuropeSub1006C=0.449T=0.551
1000GenomesGlobalStudy-wide5008C=0.400T=0.600
1000GenomesSouth AsianSub978C=0.360T=0.640
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.442T=0.558
The Genome Aggregation DatabaseAfricanSub8696C=0.520T=0.480
The Genome Aggregation DatabaseAmericanSub832C=0.360T=0.640
The Genome Aggregation DatabaseEast AsianSub1588C=0.230T=0.770
The Genome Aggregation DatabaseEuropeSub18458C=0.405T=0.594
The Genome Aggregation DatabaseGlobalStudy-wide29876C=0.430T=0.569
The Genome Aggregation DatabaseOtherSub302C=0.580T=0.420
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.467T=0.532
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.453T=0.547
PMID Title Author Journal
17158188Novel genes identified in a high-density genome wide association study for nicotine dependence.Bierut LJHum Mol Genet

P-Value

SNP ID p-value Traits Study
rs17140810.000433nicotine dependence17158188

eQTL of rs1714081 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs1714081 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr43593571135936297E067-1878
chr43593571135936297E068-1878
chr43593571135936297E069-1878
chr43593571135936297E071-1878
chr43593571135936297E073-1878
chr43593571135936297E082-1878