rs17158770

Homo sapiens
C>T
None
Check p-value
SNV (Single Nucleotide Variation)
T=0085 (2547/29954,GnomAD)
T=0091 (2671/29118,TOPMED)
T=0114 (572/5008,1000G)
T=0102 (392/3854,ALSPAC)
T=0103 (383/3708,TWINSUK)
chr10:2661380 (GRCh38.p7) (10p15.3)
AD
GWASdb2
1   publication(s)
See rs on genome
9 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 10NC_000010.11:g.2661380C>T
GRCh37.p13 chr 10NC_000010.10:g.2703572C>T

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.949T=0.051
1000GenomesAmericanSub694C=0.930T=0.070
1000GenomesEast AsianSub1008C=0.799T=0.201
1000GenomesEuropeSub1006C=0.895T=0.105
1000GenomesGlobalStudy-wide5008C=0.886T=0.114
1000GenomesSouth AsianSub978C=0.850T=0.150
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.898T=0.102
The Genome Aggregation DatabaseAfricanSub8734C=0.931T=0.069
The Genome Aggregation DatabaseAmericanSub838C=0.950T=0.050
The Genome Aggregation DatabaseEast AsianSub1610C=0.798T=0.202
The Genome Aggregation DatabaseEuropeSub18470C=0.916T=0.083
The Genome Aggregation DatabaseGlobalStudy-wide29954C=0.915T=0.085
The Genome Aggregation DatabaseOtherSub302C=0.910T=0.090
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.908T=0.091
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.897T=0.103
PMID Title Author Journal
24277619ALDH2 is associated to alcohol dependence and is the major genetic determinant of "daily maximum drinks" in a GWAS study of an isolated rural Chinese sample.Quillen EEAm J Med Genet B Neuropsychiatr Genet

P-Value

SNP ID p-value Traits Study
rs171587700.000989alcohol dependence24277619

eQTL of rs17158770 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs17158770 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr1026535992653704E070-49868
chr1027239102724020E07020338
chr1027241532724497E07020581
chr1027234852723635E08119913
chr1027236972723760E08120125
chr1027239102724020E08120338
chr1027457362745816E08142164
chr1027459342746041E08142362
chr1027460942746158E08142522