rs17161951

Homo sapiens
C>T
None
Check p-value
SNV (Single Nucleotide Variation)
T=0217 (6508/29916,GnomAD)
T=0200 (5835/29118,TOPMED)
T=0284 (1423/5008,1000G)
T=0173 (665/3854,ALSPAC)
T=0177 (657/3708,TWINSUK)
chr5:109594889 (GRCh38.p7) (5q21.3)
AD
GWASdb2
1   publication(s)
See rs on genome
122 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 5NC_000005.10:g.109594889C>T
GRCh37.p13 chr 5NC_000005.9:g.108930590C>T

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.868T=0.132
1000GenomesAmericanSub694C=0.640T=0.360
1000GenomesEast AsianSub1008C=0.491T=0.509
1000GenomesEuropeSub1006C=0.781T=0.219
1000GenomesGlobalStudy-wide5008C=0.716T=0.284
1000GenomesSouth AsianSub978C=0.730T=0.270
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.827T=0.173
The Genome Aggregation DatabaseAfricanSub8704C=0.850T=0.150
The Genome Aggregation DatabaseAmericanSub838C=0.590T=0.410
The Genome Aggregation DatabaseEast AsianSub1608C=0.479T=0.521
The Genome Aggregation DatabaseEuropeSub18464C=0.786T=0.213
The Genome Aggregation DatabaseGlobalStudy-wide29916C=0.782T=0.217
The Genome Aggregation DatabaseOtherSub302C=0.760T=0.240
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.799T=0.200
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.823T=0.177
PMID Title Author Journal
24277619ALDH2 is associated to alcohol dependence and is the major genetic determinant of "daily maximum drinks" in a GWAS study of an isolated rural Chinese sample.Quillen EEAm J Med Genet B Neuropsychiatr Genet

P-Value

SNP ID p-value Traits Study
rs171619510.000114alcohol dependence24277619

eQTL of rs17161951 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
Chr5:108930590CTD-2587M2.1ENSG00000249476.1C>T1.1474e-3268520Nucleus_accumbens_basal_ganglia

meQTL of rs17161951 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr5108897683108897874E067-32716
chr5108897944108898067E067-32523
chr5108898156108898489E067-32101
chr5108926605108926765E067-3825
chr5108948167108948257E06717577
chr5108948334108948564E06717744
chr5108948728108948828E06718138
chr5108950051108950243E06719461
chr5108950289108950354E06719699
chr5108951900108951950E06721310
chr5108953310108953403E06722720
chr5108953642108953714E06723052
chr5108954754108954904E06724164
chr5108955064108955247E06724474
chr5108955287108955924E06724697
chr5108955967108956017E06725377
chr5108965914108966089E06735324
chr5108966155108966217E06735565
chr5108894241108894306E068-36284
chr5108894382108894422E068-36168
chr5108894709108894932E068-35658
chr5108917389108917751E068-12839
chr5108948167108948257E06817577
chr5108948334108948564E06817744
chr5108948728108948828E06818138
chr5108950051108950243E06819461
chr5108950289108950354E06819699
chr5108951900108951950E06821310
chr5108953310108953403E06822720
chr5108953642108953714E06823052
chr5108954754108954904E06824164
chr5108955064108955247E06824474
chr5108955287108955924E06824697
chr5108955967108956017E06825377
chr5108957075108957230E06826485
chr5108965914108966089E06835324
chr5108966155108966217E06835565
chr5108948167108948257E06917577
chr5108948334108948564E06917744
chr5108948728108948828E06918138
chr5108950051108950243E06919461
chr5108950289108950354E06919699
chr5108951900108951950E06921310
chr5108953310108953403E06922720
chr5108953642108953714E06923052
chr5108954754108954904E06924164
chr5108955064108955247E06924474
chr5108955287108955924E06924697
chr5108955967108956017E06925377
chr5108965050108965112E06934460
chr5108965914108966089E06935324
chr5108966155108966217E06935565
chr5108954754108954904E07024164
chr5108955064108955247E07024474
chr5108955287108955924E07024697
chr5108955967108956017E07025377
chr5108965050108965112E07034460
chr5108965914108966089E07035324
chr5108966155108966217E07035565
chr5108897683108897874E071-32716
chr5108897944108898067E071-32523
chr5108898156108898489E071-32101
chr5108948167108948257E07117577
chr5108948334108948564E07117744
chr5108948728108948828E07118138
chr5108950051108950243E07119461
chr5108950289108950354E07119699
chr5108951900108951950E07121310
chr5108953310108953403E07122720
chr5108953642108953714E07123052
chr5108954754108954904E07124164
chr5108955064108955247E07124474
chr5108955287108955924E07124697
chr5108955967108956017E07125377
chr5108965050108965112E07134460
chr5108965914108966089E07135324
chr5108966155108966217E07135565
chr5108897944108898067E072-32523
chr5108898156108898489E072-32101
chr5108931475108931743E072885
chr5108931871108931923E0721281
chr5108932847108932983E0722257
chr5108948167108948257E07217577
chr5108948334108948564E07217744
chr5108948728108948828E07218138
chr5108950051108950243E07219461
chr5108950289108950354E07219699
chr5108951900108951950E07221310
chr5108953310108953403E07222720
chr5108953642108953714E07223052
chr5108954754108954904E07224164
chr5108955064108955247E07224474
chr5108955287108955924E07224697
chr5108955967108956017E07225377
chr5108957075108957230E07226485
chr5108965914108966089E07235324
chr5108966155108966217E07235565
chr5108948167108948257E07317577
chr5108948334108948564E07317744
chr5108948728108948828E07318138
chr5108954754108954904E07324164
chr5108955064108955247E07324474
chr5108955287108955924E07324697
chr5108955967108956017E07325377
chr5108920225108920328E074-10262
chr5108937454108937560E0746864
chr5108937573108937732E0746983
chr5108948167108948257E07417577
chr5108948334108948564E07417744
chr5108948728108948828E07418138
chr5108950051108950243E07419461
chr5108950289108950354E07419699
chr5108951900108951950E07421310
chr5108953310108953403E07422720
chr5108953642108953714E07423052
chr5108954754108954904E07424164
chr5108955064108955247E07424474
chr5108955287108955924E07424697
chr5108955967108956017E07425377
chr5108965050108965112E07434460
chr5108965914108966089E07435324
chr5108966155108966217E07435565