rs17168021

Homo sapiens
T>C
None
Check p-value
SNV (Single Nucleotide Variation)
C=0274 (8206/29938,GnomAD)
C=0268 (7809/29118,TOPMED)
C=0232 (1163/5008,1000G)
C=0298 (1150/3854,ALSPAC)
C=0313 (1159/3708,TWINSUK)
chr7:96913670 (GRCh38.p7) (7q21.3)
AD
GWASdb2
1   publication(s)
See rs on genome
2 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 7NC_000007.14:g.96913670T>C
GRCh37.p13 chr 7NC_000007.13:g.96542982T>C

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.775C=0.225
1000GenomesAmericanSub694T=0.730C=0.270
1000GenomesEast AsianSub1008T=0.895C=0.105
1000GenomesEuropeSub1006T=0.687C=0.313
1000GenomesGlobalStudy-wide5008T=0.768C=0.232
1000GenomesSouth AsianSub978T=0.740C=0.260
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.702C=0.298
The Genome Aggregation DatabaseAfricanSub8710T=0.768C=0.232
The Genome Aggregation DatabaseAmericanSub838T=0.760C=0.240
The Genome Aggregation DatabaseEast AsianSub1610T=0.891C=0.109
The Genome Aggregation DatabaseEuropeSub18478T=0.691C=0.308
The Genome Aggregation DatabaseGlobalStudy-wide29938T=0.725C=0.274
The Genome Aggregation DatabaseOtherSub302T=0.620C=0.380
Trans-Omics for Precision MedicineGlobalStudy-wide29118T=0.731C=0.268
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.687C=0.313
PMID Title Author Journal
24277619ALDH2 is associated to alcohol dependence and is the major genetic determinant of "daily maximum drinks" in a GWAS study of an isolated rural Chinese sample.Quillen EEAm J Med Genet B Neuropsychiatr Genet

P-Value

SNP ID p-value Traits Study
rs171680210.000135alcohol dependence24277619

eQTL of rs17168021 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs17168021 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr79655061096550828E0707628
chr79655087296551049E0707890