rs17175889

Homo sapiens
T>G
None
Check p-value
SNV (Single Nucleotide Variation)
G=0126 (3788/29936,GnomAD)
G=0103 (3024/29118,TOPMED)
G=0090 (450/5008,1000G)
G=0174 (672/3854,ALSPAC)
G=0177 (658/3708,TWINSUK)
chr9:12206873 (GRCh38.p7) (9p23)
ND
GWASdb2
1   publication(s)
See rs on genome
11 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 9NC_000009.12:g.12206873T>G
GRCh37.p13 chr 9NC_000009.11:g.12206873T>G

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.995G=0.005
1000GenomesAmericanSub694T=0.900G=0.100
1000GenomesEast AsianSub1008T=0.906G=0.094
1000GenomesEuropeSub1006T=0.842G=0.158
1000GenomesGlobalStudy-wide5008T=0.910G=0.090
1000GenomesSouth AsianSub978T=0.880G=0.120
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.826G=0.174
The Genome Aggregation DatabaseAfricanSub8730T=0.969G=0.031
The Genome Aggregation DatabaseAmericanSub834T=0.880G=0.120
The Genome Aggregation DatabaseEast AsianSub1616T=0.893G=0.107
The Genome Aggregation DatabaseEuropeSub18454T=0.826G=0.173
The Genome Aggregation DatabaseGlobalStudy-wide29936T=0.873G=0.126
The Genome Aggregation DatabaseOtherSub302T=0.840G=0.160
Trans-Omics for Precision MedicineGlobalStudy-wide29118T=0.896G=0.103
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.823G=0.177
PMID Title Author Journal
17158188Novel genes identified in a high-density genome wide association study for nicotine dependence.Bierut LJHum Mol Genet

P-Value

SNP ID p-value Traits Study
rs171758890.000779nicotine dependence17158188

eQTL of rs17175889 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs17175889 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr91216285112163111E067-43762
chr91216285112163111E070-43762
chr91216383912164060E070-42813
chr91216437412164482E070-42391
chr91221361612213668E0706743
chr91221384812214013E0706975
chr91216285112163111E071-43762
chr91221384812214013E0716975
chr91216581112165950E074-40923
chr91216285112163111E081-43762
chr91216285112163111E082-43762