rs1721013

Homo sapiens
C>T
None
Check p-value
SNV (Single Nucleotide Variation)
T=0388 (11613/29872,GnomAD)
T=0384 (11183/29118,TOPMED)
T=0461 (2309/5008,1000G)
T=0404 (1558/3854,ALSPAC)
T=0391 (1449/3708,TWINSUK)
chr7:16969977 (GRCh38.p7) (7p21.1)
AD
GWASdb2
1   publication(s)
See rs on genome
53 Enhancers around
2 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 7NC_000007.14:g.16969977C>T
GRCh37.p13 chr 7NC_000007.13:g.17009601C>T

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.707T=0.293
1000GenomesAmericanSub694C=0.540T=0.460
1000GenomesEast AsianSub1008C=0.317T=0.683
1000GenomesEuropeSub1006C=0.603T=0.397
1000GenomesGlobalStudy-wide5008C=0.539T=0.461
1000GenomesSouth AsianSub978C=0.470T=0.530
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.596T=0.404
The Genome Aggregation DatabaseAfricanSub8690C=0.661T=0.339
The Genome Aggregation DatabaseAmericanSub836C=0.560T=0.440
The Genome Aggregation DatabaseEast AsianSub1608C=0.367T=0.633
The Genome Aggregation DatabaseEuropeSub18436C=0.611T=0.388
The Genome Aggregation DatabaseGlobalStudy-wide29872C=0.611T=0.388
The Genome Aggregation DatabaseOtherSub302C=0.640T=0.360
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.615T=0.384
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.609T=0.391
PMID Title Author Journal
21314694Genomewide association analysis of symptoms of alcohol dependence in the molecular genetics of schizophrenia (MGS2) control sample.Kendler KSAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs17210138.98E-05alcohol dependence21314694

eQTL of rs1721013 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs1721013 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr71699177816992027E067-17574
chr71701074317010952E0671142
chr71701112817011200E0671527
chr71703029817030479E06720697
chr71702217117023105E06812570
chr71702311217023197E06813511
chr71703052117030654E06820920
chr71703068817030923E06821087
chr71703092617030987E06821325
chr71703105217031189E06821451
chr71702217117023105E06912570
chr71702311217023197E06913511
chr71702327417023324E06913673
chr71702351617023566E06913915
chr71703029817030479E06920697
chr71703272117032771E06923120
chr71703311117033175E06923510
chr71703319317033454E06923592
chr71696128416961921E070-47680
chr71702205917022119E07112458
chr71702217117023105E07112570
chr71702311217023197E07113511
chr71702327417023324E07113673
chr71702351617023566E07113915
chr71702392017024398E07114319
chr71703029817030479E07120697
chr71703052117030654E07120920
chr71703068817030923E07121087
chr71703092617030987E07121325
chr71703105217031189E07121451
chr71705041717050548E07140816
chr71702205917022119E07212458
chr71702217117023105E07212570
chr71702311217023197E07213511
chr71702327417023324E07213673
chr71702392017024398E07214319
chr71703029817030479E07220697
chr71703052117030654E07220920
chr71703068817030923E07221087
chr71703092617030987E07221325
chr71703029817030479E07320697
chr71703052117030654E07320920
chr71696128416961921E074-47680
chr71696202016962239E074-47362
chr71702217117023105E07412570
chr71702311217023197E07413511
chr71702327417023324E07413673
chr71702351617023566E07413915
chr71703029817030479E07420697
chr71703052117030654E07420920
chr71703068817030923E07421087
chr71703092617030987E07421325
chr71703272117032771E07423120








Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr71699139716991579E069-18022
chr71699139716991579E071-18022