rs17212908

Homo sapiens
C>T
None
Check p-value
SNV (Single Nucleotide Variation)
T=0120 (3609/29962,GnomAD)
T=0136 (3966/29118,TOPMED)
T=0092 (460/5008,1000G)
T=0099 (383/3854,ALSPAC)
T=0091 (336/3708,TWINSUK)
chr18:68427994 (GRCh38.p7) (18q22.1)
AD
GWASdb2
1   publication(s)
See rs on genome
31 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 18NC_000018.10:g.68427994C>T
GRCh37.p13 chr 18NC_000018.9:g.66095231C>T

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.791T=0.209
1000GenomesAmericanSub694C=0.950T=0.050
1000GenomesEast AsianSub1008C=1.000T=0.000
1000GenomesEuropeSub1006C=0.898T=0.102
1000GenomesGlobalStudy-wide5008C=0.908T=0.092
1000GenomesSouth AsianSub978C=0.960T=0.040
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.901T=0.099
The Genome Aggregation DatabaseAfricanSub8718C=0.805T=0.195
The Genome Aggregation DatabaseAmericanSub838C=0.950T=0.050
The Genome Aggregation DatabaseEast AsianSub1606C=1.000T=0.000
The Genome Aggregation DatabaseEuropeSub18498C=0.899T=0.100
The Genome Aggregation DatabaseGlobalStudy-wide29962C=0.879T=0.120
The Genome Aggregation DatabaseOtherSub302C=0.930T=0.070
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.863T=0.136
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.909T=0.091
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs172129080.00076alcohol dependence20201924

eQTL of rs17212908 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs17212908 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr186609479466095112E067-119
chr186609512866095932E0670
chr186609597966096204E067748
chr186609479466095112E069-119
chr186609512866095932E0690
chr186610619566106610E06910964
chr186610661666106756E06911385
chr186609597966096204E070748
chr186609624566096660E0701014
chr186610619566106610E07010964
chr186610661666106756E07011385
chr186610759466107644E07012363
chr186609512866095932E0710
chr186609479466095112E072-119
chr186609512866095932E0720
chr186609479466095112E073-119
chr186609512866095932E0730
chr186609597966096204E073748
chr186609403366094360E081-871
chr186609437766094469E081-762
chr186609479466095112E081-119
chr186609512866095932E0810
chr186609597966096204E081748
chr186609624566096660E0811014
chr186609683266096911E0811601
chr186609479466095112E082-119
chr186609512866095932E0820
chr186609597966096204E082748
chr186609624566096660E0821014
chr186609683266096911E0821601
chr186610759466107644E08212363