rs17231134

Homo sapiens
G>A / G>T
None
Check p-value
SNV (Single Nucleotide Variation)
T=0086 (2531/29118,TOPMED)
T=0091 (455/5008,1000G)
T=0121 (468/3854,ALSPAC)
T=0111 (411/3708,TWINSUK)
chr10:33790045 (GRCh38.p7) (10p11.22)
AD
GWASdb2
1   publication(s)
See rs on genome
43 Enhancers around
8 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 10NC_000010.11:g.33790045G>A
GRCh38.p7 chr 10NC_000010.11:g.33790045G>T
GRCh37.p13 chr 10NC_000010.10:g.34078973G>A
GRCh37.p13 chr 10NC_000010.10:g.34078973G>T

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.962T=0.038
1000GenomesAmericanSub694G=0.790T=0.210
1000GenomesEast AsianSub1008G=0.970T=0.030
1000GenomesEuropeSub1006G=0.880T=0.120
1000GenomesGlobalStudy-wide5008G=0.909T=0.091
1000GenomesSouth AsianSub978G=0.890T=0.110
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=0.879T=0.121
Trans-Omics for Precision MedicineGlobalStudy-wide29118G=0.913T=0.086
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.889T=0.111
PMID Title Author Journal
24277619ALDH2 is associated to alcohol dependence and is the major genetic determinant of "daily maximum drinks" in a GWAS study of an isolated rural Chinese sample.Quillen EEAm J Med Genet B Neuropsychiatr Genet

P-Value

SNP ID p-value Traits Study
rs172311340.000748alcohol consumption (maxi-drinks)24277619

eQTL of rs17231134 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs17231134 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr103103981931039901E06730262
chr103103991731040444E06730360
chr103104045731040612E06730900
chr103104067431042125E06731117
chr103103991731040444E06830360
chr103104045731040612E06830900
chr103104067431042125E06831117
chr103104045731040612E06930900
chr103104067431042125E06931117
chr103101606131016273E0716504
chr103104045731040612E07130900
chr103104067431042125E07131117
chr103104220631042421E07132649
chr103101606131016273E0726504
chr103101653131016675E0726974
chr103101679731016847E0727240
chr103101685431016921E0727297
chr103101692431016987E0727367
chr103101699431017034E0727437
chr103101713031017180E0727573
chr103103981931039901E07230262
chr103103991731040444E07230360
chr103104045731040612E07230900
chr103104067431042125E07231117
chr103101713031017180E0737573
chr103103981931039901E07330262
chr103103991731040444E07330360
chr103104045731040612E07330900
chr103103981931039901E07430262
chr103103991731040444E07430360
chr103104045731040612E07430900
chr103104067431042125E07431117
chr103096044230960510E081-49047
chr103096057130960854E081-48703
chr103098125630981775E081-27782
chr103105338831053449E08143831
chr103105403031054368E08144473
chr103105442431054512E08144867
chr103105456031054685E08145003
chr103105471631054800E08145159
chr103105486931055087E08145312
chr103105517631055238E08145619
chr103105534231055392E08145785








Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr103095983030960357E067-49200
chr103095970530959759E068-49798
chr103095983030960357E068-49200
chr103095983030960357E069-49200
chr103095983030960357E071-49200
chr103095970530959759E072-49798
chr103095983030960357E072-49200
chr103095970530959759E074-49798