rs17256536

Homo sapiens
A>G
ANXA13 : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
G=0347 (10373/29832,GnomAD)
G=0331 (9650/29118,TOPMED)
G=0316 (1583/5008,1000G)
G=0378 (1456/3854,ALSPAC)
G=0371 (1376/3708,TWINSUK)
chr8:123686935 (GRCh38.p7) (8q24.13)
AD
GWASdb2
2   publication(s)
See rs on genome
235 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 8NC_000008.11:g.123686935A>G
GRCh37.p13 chr 8NC_000008.10:g.124699175A>G

Gene: ANXA13, annexin A13(minus strand)

Molecule type Change Amino acid[Codon] SO Term
ANXA13 transcript variant 2NM_001003954.2:c.N/AIntron Variant
ANXA13 transcript variant 1NM_004306.3:c.N/AIntron Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322A=0.760G=0.240
1000GenomesAmericanSub694A=0.650G=0.350
1000GenomesEast AsianSub1008A=0.698G=0.302
1000GenomesEuropeSub1006A=0.595G=0.405
1000GenomesGlobalStudy-wide5008A=0.684G=0.316
1000GenomesSouth AsianSub978A=0.680G=0.320
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854A=0.622G=0.378
The Genome Aggregation DatabaseAfricanSub8674A=0.741G=0.259
The Genome Aggregation DatabaseAmericanSub838A=0.650G=0.350
The Genome Aggregation DatabaseEast AsianSub1620A=0.702G=0.298
The Genome Aggregation DatabaseEuropeSub18400A=0.607G=0.392
The Genome Aggregation DatabaseGlobalStudy-wide29832A=0.652G=0.347
The Genome Aggregation DatabaseOtherSub300A=0.580G=0.420
Trans-Omics for Precision MedicineGlobalStudy-wide29118A=0.668G=0.331
UK 10K study - TwinsTWIN COHORTStudy-wide3708A=0.629G=0.371
PMID Title Author Journal
21314694Genomewide association analysis of symptoms of alcohol dependence in the molecular genetics of schizophrenia (MGS2) control sample.Kendler KSAlcohol Clin Exp Res
26768247A substitution mutation in cardiac ubiquitin ligase, FBXO32, is associated with an autosomal recessive form of dilated cardiomyopathy.Al-Hassnan ZNBMC Med Genet

P-Value

SNP ID p-value Traits Study
rs172565360.000959alcohol dependence21314694

eQTL of rs17256536 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs17256536 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr8124656075124656727E067-42448
chr8124656768124656930E067-42245
chr8124665437124667049E067-32126
chr8124667062124667358E067-31817
chr8124670228124670359E067-28816
chr8124670430124671040E067-28135
chr8124681186124681972E067-17203
chr8124683087124684027E067-15148
chr8124684042124684272E067-14903
chr8124696681124697067E067-2108
chr8124697069124697130E067-2045
chr8124697297124697498E067-1677
chr8124697555124698275E067-900
chr8124704952124706904E0675777
chr8124717456124717781E06718281
chr8124717786124717933E06718611
chr8124718124124718178E06718949
chr8124718181124718255E06719006
chr8124725144124725460E06725969
chr8124725711124725778E06726536
chr8124726342124726662E06727167
chr8124726745124726836E06727570
chr8124726923124727024E06727748
chr8124728680124729413E06729505
chr8124730622124730903E06731447
chr8124730923124731530E06731748
chr8124731611124732739E06732436
chr8124741930124741980E06742755
chr8124670228124670359E068-28816
chr8124670430124671040E068-28135
chr8124681186124681972E068-17203
chr8124683087124684027E068-15148
chr8124699154124699224E0680
chr8124699293124700284E068118
chr8124701553124703167E0682378
chr8124703211124703599E0684036
chr8124704952124706904E0685777
chr8124717786124717933E06818611
chr8124718124124718178E06818949
chr8124718181124718255E06819006
chr8124718339124718466E06819164
chr8124725144124725460E06825969
chr8124725711124725778E06826536
chr8124726342124726662E06827167
chr8124726745124726836E06827570
chr8124726923124727024E06827748
chr8124728680124729413E06829505
chr8124731611124732739E06832436
chr8124732782124732890E06833607
chr8124741333124741739E06842158
chr8124741756124741876E06842581
chr8124741930124741980E06842755
chr8124656075124656727E069-42448
chr8124656768124656930E069-42245
chr8124667062124667358E069-31817
chr8124667363124668026E069-31149
chr8124670228124670359E069-28816
chr8124670430124671040E069-28135
chr8124681186124681972E069-17203
chr8124682029124682398E069-16777
chr8124683087124684027E069-15148
chr8124684042124684272E069-14903
chr8124697555124698275E069-900
chr8124698329124698428E069-747
chr8124701553124703167E0692378
chr8124703211124703599E0694036
chr8124704089124704942E0694914
chr8124704952124706904E0695777
chr8124707221124707281E0698046
chr8124707355124707395E0698180
chr8124717786124717933E06918611
chr8124718124124718178E06918949
chr8124718181124718255E06919006
chr8124725144124725460E06925969
chr8124726342124726662E06927167
chr8124726745124726836E06927570
chr8124728680124729413E06929505
chr8124729989124730170E06930814
chr8124730269124730319E06931094
chr8124730329124730437E06931154
chr8124730622124730903E06931447
chr8124730923124731530E06931748
chr8124731611124732739E06932436
chr8124732782124732890E06933607
chr8124733054124733440E06933879
chr8124741756124741876E06942581
chr8124741930124741980E06942755
chr8124670030124670173E070-29002
chr8124670228124670359E070-28816
chr8124670430124671040E070-28135
chr8124681186124681972E070-17203
chr8124730923124731530E07031748
chr8124731611124732739E07032436
chr8124656075124656727E071-42448
chr8124656768124656930E071-42245
chr8124670030124670173E071-29002
chr8124670228124670359E071-28816
chr8124670430124671040E071-28135
chr8124681186124681972E071-17203
chr8124682029124682398E071-16777
chr8124682467124682559E071-16616
chr8124682606124682872E071-16303
chr8124683087124684027E071-15148
chr8124696405124696621E071-2554
chr8124696681124697067E071-2108
chr8124697555124698275E071-900
chr8124699293124700284E071118
chr8124701553124703167E0712378
chr8124703211124703599E0714036
chr8124703719124703803E0714544
chr8124703828124703915E0714653
chr8124704089124704942E0714914
chr8124704952124706904E0715777
chr8124712351124712774E07113176
chr8124725144124725460E07125969
chr8124725711124725778E07126536
chr8124726342124726662E07127167
chr8124726745124726836E07127570
chr8124726923124727024E07127748
chr8124727639124728290E07128464
chr8124728680124729413E07129505
chr8124730923124731530E07131748
chr8124731611124732739E07132436
chr8124741333124741739E07142158
chr8124741756124741876E07142581
chr8124741930124741980E07142755
chr8124656075124656727E072-42448
chr8124664974124665391E072-33784
chr8124667363124668026E072-31149
chr8124670030124670173E072-29002
chr8124670228124670359E072-28816
chr8124670430124671040E072-28135
chr8124681186124681972E072-17203
chr8124682029124682398E072-16777
chr8124684042124684272E072-14903
chr8124699293124700284E072118
chr8124701553124703167E0722378
chr8124703211124703599E0724036
chr8124703719124703803E0724544
chr8124703828124703915E0724653
chr8124704089124704942E0724914
chr8124704952124706904E0725777
chr8124714800124715016E07215625
chr8124715076124715142E07215901
chr8124715155124715205E07215980
chr8124717456124717781E07218281
chr8124717786124717933E07218611
chr8124718124124718178E07218949
chr8124718181124718255E07219006
chr8124718339124718466E07219164
chr8124718885124718925E07219710
chr8124725144124725460E07225969
chr8124725711124725778E07226536
chr8124726342124726662E07227167
chr8124726745124726836E07227570
chr8124726923124727024E07227748
chr8124728680124729413E07229505
chr8124729989124730170E07230814
chr8124730269124730319E07231094
chr8124730329124730437E07231154
chr8124730622124730903E07231447
chr8124730923124731530E07231748
chr8124731611124732739E07232436
chr8124732782124732890E07233607
chr8124655671124656070E073-43105
chr8124656075124656727E073-42448
chr8124656768124656930E073-42245
chr8124667062124667358E073-31817
chr8124667363124668026E073-31149
chr8124669638124669758E073-29417
chr8124670228124670359E073-28816
chr8124670430124671040E073-28135
chr8124681186124681972E073-17203
chr8124682029124682398E073-16777
chr8124683087124684027E073-15148
chr8124684042124684272E073-14903
chr8124699293124700284E073118
chr8124701553124703167E0732378
chr8124704952124706904E0735777
chr8124718124124718178E07318949
chr8124731611124732739E07332436
chr8124655671124656070E074-43105
chr8124656075124656727E074-42448
chr8124656768124656930E074-42245
chr8124670430124671040E074-28135
chr8124680988124681058E074-18117
chr8124681062124681112E074-18063
chr8124681186124681972E074-17203
chr8124682029124682398E074-16777
chr8124683087124684027E074-15148
chr8124697555124698275E074-900
chr8124699154124699224E0740
chr8124699293124700284E074118
chr8124700486124700551E0741311
chr8124700721124700868E0741546
chr8124700907124701099E0741732
chr8124703719124703803E0744544
chr8124703828124703915E0744653
chr8124704089124704942E0744914
chr8124704952124706904E0745777
chr8124706981124707085E0747806
chr8124707221124707281E0748046
chr8124707355124707395E0748180
chr8124707673124707727E0748498
chr8124714800124715016E07415625
chr8124715076124715142E07415901
chr8124715155124715205E07415980
chr8124725144124725460E07425969
chr8124725711124725778E07426536
chr8124726342124726662E07427167
chr8124726745124726836E07427570
chr8124726923124727024E07427748
chr8124727639124728290E07428464
chr8124728680124729413E07429505
chr8124729989124730170E07430814
chr8124730269124730319E07431094
chr8124730329124730437E07431154
chr8124730622124730903E07431447
chr8124730923124731530E07431748
chr8124731611124732739E07432436
chr8124732782124732890E07433607
chr8124741756124741876E07442581
chr8124741930124741980E07442755
chr8124664974124665391E081-33784
chr8124665437124667049E081-32126
chr8124667062124667358E081-31817
chr8124667363124668026E081-31149
chr8124670228124670359E081-28816
chr8124670430124671040E081-28135
chr8124730622124730903E08131447
chr8124730923124731530E08131748
chr8124670228124670359E082-28816
chr8124670430124671040E082-28135
chr8124730923124731530E08231748
chr8124731611124732739E08232436