rs172676

Homo sapiens
A>C / A>G / A>T
None
Check p-value
SNV (Single Nucleotide Variation)
A==0315 (9438/29902,GnomAD)
A==0384 (11186/29118,TOPMED)
A==0288 (1444/5008,1000G)
A==0241 (930/3854,ALSPAC)
A==0239 (886/3708,TWINSUK)
chr5:162616844 (GRCh38.p7) (5q34)
AD
GWASdb2
1   publication(s)
See rs on genome
0 Enhancer around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 5NC_000005.10:g.162616844A>C
GRCh38.p7 chr 5NC_000005.10:g.162616844A>G
GRCh38.p7 chr 5NC_000005.10:g.162616844A>T
GRCh37.p13 chr 5NC_000005.9:g.162043850A>C
GRCh37.p13 chr 5NC_000005.9:g.162043850A>G
GRCh37.p13 chr 5NC_000005.9:g.162043850A>T

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322A=0.575G=0.425
1000GenomesAmericanSub694A=0.340G=0.660
1000GenomesEast AsianSub1008A=0.088G=0.912
1000GenomesEuropeSub1006A=0.251G=0.749
1000GenomesGlobalStudy-wide5008A=0.288G=0.712
1000GenomesSouth AsianSub978A=0.110G=0.890
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854A=0.241G=0.759
The Genome Aggregation DatabaseAfricanSub8702A=0.534G=0.466
The Genome Aggregation DatabaseAmericanSub836A=0.300G=0.700
The Genome Aggregation DatabaseEast AsianSub1616A=0.100G=0.900
The Genome Aggregation DatabaseEuropeSub18448A=0.234G=0.765
The Genome Aggregation DatabaseGlobalStudy-wide29902A=0.315G=0.684
The Genome Aggregation DatabaseOtherSub300A=0.230G=0.770
Trans-Omics for Precision MedicineGlobalStudy-wide29118A=0.384G=0.615
UK 10K study - TwinsTWIN COHORTStudy-wide3708A=0.239G=0.761
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs1726760.00092alcohol dependence20201924

eQTL of rs172676 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs172676 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.