rs17279860

Homo sapiens
A>T
CORO2B : 3 Prime UTR Variant
Check p-value
SNV (Single Nucleotide Variation)
T=0283 (8465/29876,GnomAD)
T=0274 (8001/29118,TOPMED)
T=0311 (1555/5008,1000G)
T=0291 (1120/3854,ALSPAC)
T=0294 (1091/3708,TWINSUK)
chr15:68726620 (GRCh38.p7) (15q23)
AD
GWASdb2
1   publication(s)
See rs on genome
254 Enhancers around
1 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 15NC_000015.10:g.68726620A>T
GRCh37.p13 chr 15NC_000015.9:g.69018959A>T

Gene: CORO2B, coronin 2B(plus strand)

Molecule type Change Amino acid[Codon] SO Term
CORO2B transcript variant 2NM_001190456.1:c.N/A3 Prime UTR Variant
CORO2B transcript variant 3NM_001190457.1:c.N/A3 Prime UTR Variant
CORO2B transcript variant 1NM_006091.4:c.N/A3 Prime UTR Variant
CORO2B transcript variant 5NM_001324015.1:c.N/A3 Prime UTR Variant
CORO2B transcript variant 4NM_001324014.1:c.N/A3 Prime UTR Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322A=0.805T=0.195
1000GenomesAmericanSub694A=0.530T=0.470
1000GenomesEast AsianSub1008A=0.686T=0.314
1000GenomesEuropeSub1006A=0.727T=0.273
1000GenomesGlobalStudy-wide5008A=0.689T=0.311
1000GenomesSouth AsianSub978A=0.610T=0.390
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854A=0.709T=0.291
The Genome Aggregation DatabaseAfricanSub8702A=0.788T=0.212
The Genome Aggregation DatabaseAmericanSub838A=0.480T=0.520
The Genome Aggregation DatabaseEast AsianSub1610A=0.686T=0.314
The Genome Aggregation DatabaseEuropeSub18426A=0.698T=0.301
The Genome Aggregation DatabaseGlobalStudy-wide29876A=0.716T=0.283
The Genome Aggregation DatabaseOtherSub300A=0.600T=0.400
Trans-Omics for Precision MedicineGlobalStudy-wide29118A=0.725T=0.274
UK 10K study - TwinsTWIN COHORTStudy-wide3708A=0.706T=0.294
PMID Title Author Journal
21314694Genomewide association analysis of symptoms of alcohol dependence in the molecular genetics of schizophrenia (MGS2) control sample.Kendler KSAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs172798600.000832alcohol dependence21314694

eQTL of rs17279860 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs17279860 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr156897180568972343E067-46616
chr156897245568972750E067-46209
chr156897276368973051E067-45908
chr156897397568974102E067-44857
chr156897428568974452E067-44507
chr156897461768974725E067-44234
chr156897482368974946E067-44013
chr156897503568975123E067-43836
chr156897585168975934E067-43025
chr156897598468976024E067-42935
chr156897609868976179E067-42780
chr156897620168977120E067-41839
chr156898553068985835E067-33124
chr156898596568986082E067-32877
chr156899146268991807E067-27152
chr156899181468992036E067-26923
chr156899206468992234E067-26725
chr156899228668993669E067-25290
chr156899440968994731E067-24228
chr156899475768994866E067-24093
chr156902181369023790E0672854
chr156902578869025875E0676829
chr156902589169025945E0676932
chr156903187669032016E06712917
chr156903212969032318E06713170
chr156903243669032486E06713477
chr156906390969064103E06744950
chr156906414669064191E06745187
chr156906725969068924E06748300
chr156896973068969780E068-49179
chr156896978668969916E068-49043
chr156897005968970154E068-48805
chr156897016168970358E068-48601
chr156897160368971753E068-47206
chr156897180568972343E068-46616
chr156897245568972750E068-46209
chr156897276368973051E068-45908
chr156897385868973942E068-45017
chr156897397568974102E068-44857
chr156897598468976024E068-42935
chr156897609868976179E068-42780
chr156897620168977120E068-41839
chr156898553068985835E068-33124
chr156899097868991419E068-27540
chr156899146268991807E068-27152
chr156899181468992036E068-26923
chr156899206468992234E068-26725
chr156899228668993669E068-25290
chr156899679468997474E068-21485
chr156900230569002432E068-16527
chr156900245869002679E068-16280
chr156900271869002772E068-16187
chr156900277869002828E068-16131
chr156901431969014548E068-4411
chr156901459069014665E068-4294
chr156902181369023790E0682854
chr156906725969068924E06848300
chr156896913868969202E069-49757
chr156896938068969466E069-49493
chr156896973068969780E069-49179
chr156896978668969916E069-49043
chr156897005968970154E069-48805
chr156897016168970358E069-48601
chr156897104268971298E069-47661
chr156897143268971529E069-47430
chr156897160368971753E069-47206
chr156897245568972750E069-46209
chr156897276368973051E069-45908
chr156897385868973942E069-45017
chr156897397568974102E069-44857
chr156897428568974452E069-44507
chr156897461768974725E069-44234
chr156897482368974946E069-44013
chr156897503568975123E069-43836
chr156897585168975934E069-43025
chr156897598468976024E069-42935
chr156897609868976179E069-42780
chr156897620168977120E069-41839
chr156898400368984503E069-34456
chr156898553068985835E069-33124
chr156898596568986082E069-32877
chr156899075368990903E069-28056
chr156899097868991419E069-27540
chr156899146268991807E069-27152
chr156899181468992036E069-26923
chr156899370068993744E069-25215
chr156899374868993798E069-25161
chr156899422568994311E069-24648
chr156901431969014548E069-4411
chr156901459069014665E069-4294
chr156902181369023790E0692854
chr156903243669032486E06913477
chr156906390969064103E06944950
chr156906414669064191E06945187
chr156906423269064453E06945273
chr156906725969068924E06948300
chr156899228668993669E070-25290
chr156906725969068924E07048300
chr156896913868969202E071-49757
chr156896938068969466E071-49493
chr156896973068969780E071-49179
chr156896978668969916E071-49043
chr156897005968970154E071-48805
chr156897016168970358E071-48601
chr156897054168970623E071-48336
chr156897143268971529E071-47430
chr156897160368971753E071-47206
chr156897180568972343E071-46616
chr156897245568972750E071-46209
chr156897276368973051E071-45908
chr156897385868973942E071-45017
chr156897397568974102E071-44857
chr156897428568974452E071-44507
chr156897461768974725E071-44234
chr156897482368974946E071-44013
chr156897503568975123E071-43836
chr156897585168975934E071-43025
chr156897598468976024E071-42935
chr156897609868976179E071-42780
chr156897620168977120E071-41839
chr156898553068985835E071-33124
chr156899075368990903E071-28056
chr156899097868991419E071-27540
chr156899146268991807E071-27152
chr156899181468992036E071-26923
chr156899206468992234E071-26725
chr156899228668993669E071-25290
chr156899370068993744E071-25215
chr156899374868993798E071-25161
chr156899413668994186E071-24773
chr156899422568994311E071-24648
chr156899440968994731E071-24228
chr156899475768994866E071-24093
chr156899679468997474E071-21485
chr156901431969014548E071-4411
chr156901459069014665E071-4294
chr156901471969014915E071-4044
chr156902181369023790E0712854
chr156902578869025875E0716829
chr156902589169025945E0716932
chr156903243669032486E07113477
chr156903280069032840E07113841
chr156906390969064103E07144950
chr156906414669064191E07145187
chr156906423269064453E07145273
chr156906660869066735E07147649
chr156906695669067052E07147997
chr156906725969068924E07148300
chr156896913868969202E072-49757
chr156897005968970154E072-48805
chr156897016168970358E072-48601
chr156897054168970623E072-48336
chr156897075968970809E072-48150
chr156897104268971298E072-47661
chr156897143268971529E072-47430
chr156897160368971753E072-47206
chr156897180568972343E072-46616
chr156897245568972750E072-46209
chr156897276368973051E072-45908
chr156897385868973942E072-45017
chr156897397568974102E072-44857
chr156897428568974452E072-44507
chr156897461768974725E072-44234
chr156897482368974946E072-44013
chr156897503568975123E072-43836
chr156897585168975934E072-43025
chr156897598468976024E072-42935
chr156897609868976179E072-42780
chr156898400368984503E072-34456
chr156899055868990617E072-28342
chr156899075368990903E072-28056
chr156899097868991419E072-27540
chr156899146268991807E072-27152
chr156899181468992036E072-26923
chr156899206468992234E072-26725
chr156899679468997474E072-21485
chr156900271869002772E072-16187
chr156901459069014665E072-4294
chr156902181369023790E0722854
chr156902658269026869E0727623
chr156903280069032840E07213841
chr156906725969068924E07248300
chr156897005968970154E073-48805
chr156897016168970358E073-48601
chr156897180568972343E073-46616
chr156897397568974102E073-44857
chr156897428568974452E073-44507
chr156897585168975934E073-43025
chr156897620168977120E073-41839
chr156898400368984503E073-34456
chr156899181468992036E073-26923
chr156899206468992234E073-26725
chr156899679468997474E073-21485
chr156900245869002679E073-16280
chr156900271869002772E073-16187
chr156900277869002828E073-16131
chr156900297969003040E073-15919
chr156902181369023790E0732854
chr156903187669032016E07312917
chr156903212969032318E07313170
chr156903243669032486E07313477
chr156906390969064103E07344950
chr156906414669064191E07345187
chr156906423269064453E07345273
chr156906725969068924E07348300
chr156896913868969202E074-49757
chr156896938068969466E074-49493
chr156896973068969780E074-49179
chr156896978668969916E074-49043
chr156897005968970154E074-48805
chr156897016168970358E074-48601
chr156897054168970623E074-48336
chr156897075968970809E074-48150
chr156897104268971298E074-47661
chr156897143268971529E074-47430
chr156897160368971753E074-47206
chr156897245568972750E074-46209
chr156897276368973051E074-45908
chr156897385868973942E074-45017
chr156897397568974102E074-44857
chr156897428568974452E074-44507
chr156897461768974725E074-44234
chr156897482368974946E074-44013
chr156897503568975123E074-43836
chr156897585168975934E074-43025
chr156897598468976024E074-42935
chr156897609868976179E074-42780
chr156897620168977120E074-41839
chr156898553068985835E074-33124
chr156898596568986082E074-32877
chr156898725668987384E074-31575
chr156899075368990903E074-28056
chr156899097868991419E074-27540
chr156899146268991807E074-27152
chr156899181468992036E074-26923
chr156899206468992234E074-26725
chr156901431969014548E074-4411
chr156901459069014665E074-4294
chr156902181369023790E0742854
chr156902658269026869E0747623
chr156903243669032486E07413477
chr156906725969068924E07448300
chr156899075368990903E081-28056
chr156899097868991419E081-27540
chr156899146268991807E081-27152
chr156899181468992036E081-26923
chr156899206468992234E081-26725
chr156899228668993669E081-25290
chr156906725969068924E08148300
chr156898400368984503E082-34456
chr156899055868990617E082-28342
chr156899146268991807E082-27152
chr156899181468992036E082-26923
chr156899206468992234E082-26725










Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr156904707969047627E07128120