rs17284420

Homo sapiens
G>C
None
Check p-value
SNV (Single Nucleotide Variation)
C=0081 (2425/29830,GnomAD)
C=0080 (2351/29118,TOPMED)
C=0070 (353/5008,1000G)
C=0099 (382/3854,ALSPAC)
C=0091 (336/3708,TWINSUK)
chr5:83417201 (GRCh38.p7) (5q14.2)
ND
GWASdb2
1   publication(s)
See rs on genome
19 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 5NC_000005.10:g.83417201G>C
GRCh37.p13 chr 5NC_000005.9:g.82713020G>C

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.955C=0.045
1000GenomesAmericanSub694G=0.950C=0.050
1000GenomesEast AsianSub1008G=0.963C=0.037
1000GenomesEuropeSub1006G=0.914C=0.086
1000GenomesGlobalStudy-wide5008G=0.930C=0.070
1000GenomesSouth AsianSub978G=0.860C=0.140
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=0.901C=0.099
The Genome Aggregation DatabaseAfricanSub8710G=0.944C=0.056
The Genome Aggregation DatabaseAmericanSub832G=0.930C=0.070
The Genome Aggregation DatabaseEast AsianSub1568G=0.962C=0.038
The Genome Aggregation DatabaseEuropeSub18418G=0.904C=0.095
The Genome Aggregation DatabaseGlobalStudy-wide29830G=0.918C=0.081
The Genome Aggregation DatabaseOtherSub302G=0.760C=0.240
Trans-Omics for Precision MedicineGlobalStudy-wide29118G=0.919C=0.080
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.909C=0.091
PMID Title Author Journal
19268276Genome-wide association study of smoking initiation and current smoking.Vink JMAm J Hum Genet

P-Value

SNP ID p-value Traits Study
rs172844200.0001nicotine smoking19268276

eQTL of rs17284420 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs17284420 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr58274794182748112E06934921
chr58274823082748359E06935210
chr58271427882714470E0701258
chr58271455982714609E0701539
chr58271464382714767E0701623
chr58271482182714919E0701801
chr58274352182743593E07030501
chr58274431082744420E07031290
chr58274617782746343E07033157
chr58274641282746977E07033392
chr58274707182747163E07034051
chr58274773182747781E07034711
chr58274794182748112E07034921
chr58274823082748359E07035210
chr58274844982748499E07035429
chr58272674482726835E07113724
chr58271427882714470E0821258
chr58271599082716492E0822970
chr58274794182748112E08234921