rs1744061

Homo sapiens
C>T
IL20RA : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
T=0196 (5871/29946,GnomAD)
T=0168 (4917/29118,TOPMED)
T=0131 (656/5008,1000G)
T=0284 (1094/3854,ALSPAC)
T=0276 (1025/3708,TWINSUK)
chr6:137003518 (GRCh38.p7) (6q23.3)
AD
GWASdb2
1   publication(s)
See rs on genome
12 Enhancers around
15 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 6NC_000006.12:g.137003518C>T
GRCh37.p13 chr 6NC_000006.11:g.137324655C>T

Gene: IL20RA, interleukin 20 receptor subunit alpha(minus strand)

Molecule type Change Amino acid[Codon] SO Term
IL20RA transcript variant 2NM_001278722.1:c.N/AIntron Variant
IL20RA transcript variant 3NM_001278723.1:c.N/AIntron Variant
IL20RA transcript variant 4NM_001278724.1:c.N/AIntron Variant
IL20RA transcript variant 1NM_014432.3:c.N/AIntron Variant
IL20RA transcript variant X4XM_006715506.2:c.N/AIntron Variant
IL20RA transcript variant X3XM_011535904.2:c.N/AIntron Variant
IL20RA transcript variant X1XM_017010954.1:c.N/AIntron Variant
IL20RA transcript variant X2XM_017010955.1:c.N/AIntron Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.989T=0.011
1000GenomesAmericanSub694C=0.770T=0.230
1000GenomesEast AsianSub1008C=0.901T=0.099
1000GenomesEuropeSub1006C=0.735T=0.265
1000GenomesGlobalStudy-wide5008C=0.869T=0.131
1000GenomesSouth AsianSub978C=0.880T=0.120
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.716T=0.284
The Genome Aggregation DatabaseAfricanSub8722C=0.949T=0.051
The Genome Aggregation DatabaseAmericanSub838C=0.790T=0.210
The Genome Aggregation DatabaseEast AsianSub1620C=0.864T=0.136
The Genome Aggregation DatabaseEuropeSub18466C=0.731T=0.268
The Genome Aggregation DatabaseGlobalStudy-wide29946C=0.803T=0.196
The Genome Aggregation DatabaseOtherSub300C=0.790T=0.210
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.831T=0.168
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.724T=0.276
PMID Title Author Journal
24277619ALDH2 is associated to alcohol dependence and is the major genetic determinant of "daily maximum drinks" in a GWAS study of an isolated rural Chinese sample.Quillen EEAm J Med Genet B Neuropsychiatr Genet

P-Value

SNP ID p-value Traits Study
rs17440610.000514alcohol dependence24277619

eQTL of rs1744061 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs1744061 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr6137277780137278786E068-45869
chr6137277780137278786E070-45869
chr6137283020137283280E070-41375
chr6137283326137283439E070-41216
chr6137283513137283563E070-41092
chr6137283688137284398E070-40257
chr6137284416137284752E070-39903
chr6137277780137278786E071-45869
chr6137310297137310449E072-14206
chr6137283688137284398E082-40257
chr6137284416137284752E082-39903
chr6137310297137310449E082-14206





Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr6137364801137366561E06740146
chr6137310498137311535E068-13120
chr6137364801137366561E06840146
chr6137364801137366561E06940146
chr6137310498137311535E070-13120
chr6137364801137366561E07040146
chr6137310498137311535E071-13120
chr6137364801137366561E07140146
chr6137364801137366561E07240146
chr6137310498137311535E073-13120
chr6137364801137366561E07340146
chr6137364801137366561E07440146
chr6137311622137311687E082-12968
chr6137311765137311851E082-12804
chr6137364801137366561E08240146