rs17473320

Homo sapiens
C>T
None
Check p-value
SNV (Single Nucleotide Variation)
T=0418 (12523/29946,GnomAD)
T=0380 (11086/29118,TOPMED)
T=0443 (2217/5008,1000G)
C==0481 (1854/3854,ALSPAC)
C==0477 (1768/3708,TWINSUK)
chr11:116258300 (GRCh38.p7) (11q23.3)
AD
GWASdb2
1   publication(s)
See rs on genome
177 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 11NC_000011.10:g.116258300C>T
GRCh37.p13 chr 11NC_000011.9:g.116129017C>T

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.811T=0.189
1000GenomesAmericanSub694C=0.590T=0.410
1000GenomesEast AsianSub1008C=0.485T=0.515
1000GenomesEuropeSub1006C=0.472T=0.528
1000GenomesGlobalStudy-wide5008C=0.557T=0.443
1000GenomesSouth AsianSub978C=0.360T=0.640
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.481T=0.519
The Genome Aggregation DatabaseAfricanSub8722C=0.779T=0.221
The Genome Aggregation DatabaseAmericanSub838C=0.610T=0.390
The Genome Aggregation DatabaseEast AsianSub1614C=0.493T=0.507
The Genome Aggregation DatabaseEuropeSub18470C=0.496T=0.503
The Genome Aggregation DatabaseGlobalStudy-wide29946C=0.581T=0.418
The Genome Aggregation DatabaseOtherSub302C=0.530T=0.470
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.619T=0.380
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.477T=0.523
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs174733200.0000879alcoholismpha002893
rs174733200.000088alcohol dependence20201924
rs174733200.00033alcohol dependence(early age of onset)20201924

eQTL of rs17473320 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs17473320 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr11116089825116089984E067-39033
chr11116095592116095644E067-33373
chr11116095694116095765E067-33252
chr11116095804116096349E067-32668
chr11116095592116095644E068-33373
chr11116095694116095765E068-33252
chr11116099906116101440E068-27577
chr11116127862116128078E068-939
chr11116133891116134128E0684874
chr11116089720116089802E069-39215
chr11116089825116089984E069-39033
chr11116090062116090437E069-38580
chr11116095189116095526E069-33491
chr11116095592116095644E069-33373
chr11116095694116095765E069-33252
chr11116146992116148073E06917975
chr11116087692116088108E070-40909
chr11116090062116090437E070-38580
chr11116090459116090536E070-38481
chr11116094790116094855E070-34162
chr11116095037116095119E070-33898
chr11116095189116095526E070-33491
chr11116095592116095644E070-33373
chr11116095694116095765E070-33252
chr11116095804116096349E070-32668
chr11116096354116096463E070-32554
chr11116096588116096789E070-32228
chr11116099356116099477E070-29540
chr11116099519116099573E070-29444
chr11116099906116101440E070-27577
chr11116101508116101564E070-27453
chr11116101588116101684E070-27333
chr11116101846116101933E070-27084
chr11116102142116102668E070-26349
chr11116102787116102841E070-26176
chr11116103046116103101E070-25916
chr11116103133116103547E070-25470
chr11116103566116103710E070-25307
chr11116103799116103986E070-25031
chr11116104186116104374E070-24643
chr11116104419116104679E070-24338
chr11116113708116113782E070-15235
chr11116113863116113913E070-15104
chr11116113940116113990E070-15027
chr11116114823116114863E070-14154
chr11116114872116114984E070-14033
chr11116114994116115094E070-13923
chr11116115422116115658E070-13359
chr11116115669116115940E070-13077
chr11116120645116120695E070-8322
chr11116133279116133345E0704262
chr11116133426116133511E0704409
chr11116133516116133566E0704499
chr11116133891116134128E0704874
chr11116134195116134902E0705178
chr11116134996116135069E0705979
chr11116136393116136443E0707376
chr11116136598116136687E0707581
chr11116136712116136759E0707695
chr11116137006116137218E0707989
chr11116137366116137446E0708349
chr11116137818116137899E0708801
chr11116138000116138126E0708983
chr11116143100116143199E07014083
chr11116144276116144347E07015259
chr11116144512116144570E07015495
chr11116144870116144920E07015853
chr11116145010116145973E07015993
chr11116146041116146091E07017024
chr11116146122116146179E07017105
chr11116146455116146643E07017438
chr11116146827116146990E07017810
chr11116146992116148073E07017975
chr11116148123116148187E07019106
chr11116149494116149683E07020477
chr11116149740116149823E07020723
chr11116150195116150728E07021178
chr11116150970116151021E07021953
chr11116155376116155466E07026359
chr11116155756116156105E07026739
chr11116156163116156293E07027146
chr11116171030116171074E07042013
chr11116171148116171273E07042131
chr11116171617116171667E07042600
chr11116095037116095119E071-33898
chr11116095189116095526E071-33491
chr11116095592116095644E071-33373
chr11116095694116095765E071-33252
chr11116095804116096349E071-32668
chr11116095592116095644E072-33373
chr11116095694116095765E072-33252
chr11116095804116096349E072-32668
chr11116133891116134128E0724874
chr11116089720116089802E073-39215
chr11116089825116089984E073-39033
chr11116090062116090437E073-38580
chr11116090459116090536E073-38481
chr11116094656116094732E073-34285
chr11116094790116094855E073-34162
chr11116095189116095526E073-33491
chr11116095592116095644E073-33373
chr11116095694116095765E073-33252
chr11116136712116136759E0737695
chr11116146827116146990E07317810
chr11116146992116148073E07317975
chr11116090062116090437E081-38580
chr11116090459116090536E081-38481
chr11116095189116095526E081-33491
chr11116095592116095644E081-33373
chr11116095694116095765E081-33252
chr11116095804116096349E081-32668
chr11116096354116096463E081-32554
chr11116096588116096789E081-32228
chr11116099906116101440E081-27577
chr11116101508116101564E081-27453
chr11116101588116101684E081-27333
chr11116101846116101933E081-27084
chr11116120645116120695E081-8322
chr11116133426116133511E0814409
chr11116133516116133566E0814499
chr11116133891116134128E0814874
chr11116134195116134902E0815178
chr11116134996116135069E0815979
chr11116141106116141156E08112089
chr11116141462116141717E08112445
chr11116141981116142083E08112964
chr11116142476116142516E08113459
chr11116143100116143199E08114083
chr11116144276116144347E08115259
chr11116144512116144570E08115495
chr11116144870116144920E08115853
chr11116145010116145973E08115993
chr11116146041116146091E08117024
chr11116146122116146179E08117105
chr11116146455116146643E08117438
chr11116146827116146990E08117810
chr11116146992116148073E08117975
chr11116149494116149683E08120477
chr11116149740116149823E08120723
chr11116150195116150728E08121178
chr11116150970116151021E08121953
chr11116155376116155466E08126359
chr11116155756116156105E08126739
chr11116156163116156293E08127146
chr11116156915116156965E08127898
chr11116158328116158609E08129311
chr11116158700116158867E08129683
chr11116172408116172503E08143391
chr11116173358116173443E08144341
chr11116173500116174072E08144483
chr11116090062116090437E082-38580
chr11116090459116090536E082-38481
chr11116095189116095526E082-33491
chr11116095592116095644E082-33373
chr11116095694116095765E082-33252
chr11116095804116096349E082-32668
chr11116096354116096463E082-32554
chr11116096588116096789E082-32228
chr11116099906116101440E082-27577
chr11116101508116101564E082-27453
chr11116101588116101684E082-27333
chr11116133891116134128E0824874
chr11116134195116134902E0825178
chr11116136598116136687E0827581
chr11116136712116136759E0827695
chr11116137006116137218E0827989
chr11116137366116137446E0828349
chr11116144512116144570E08215495
chr11116144870116144920E08215853
chr11116145010116145973E08215993
chr11116146041116146091E08217024
chr11116146122116146179E08217105
chr11116155756116156105E08226739
chr11116156163116156293E08227146
chr11116156915116156965E08227898
chr11116173358116173443E08244341
chr11116173500116174072E08244483