rs17478537

Homo sapiens
T>C
None
Check p-value
SNV (Single Nucleotide Variation)
C=0149 (4472/29960,GnomAD)
C=0162 (4728/29118,TOPMED)
C=0108 (543/5008,1000G)
C=0160 (616/3854,ALSPAC)
C=0145 (538/3708,TWINSUK)
chr2:203594456 (GRCh38.p7) (2q33.2)
AD
GWASdb2
1   publication(s)
See rs on genome
25 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 2NC_000002.12:g.203594456T>C
GRCh37.p13 chr 2NC_000002.11:g.204459179T>C

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.846C=0.154
1000GenomesAmericanSub694T=0.900C=0.100
1000GenomesEast AsianSub1008T=0.937C=0.063
1000GenomesEuropeSub1006T=0.837C=0.163
1000GenomesGlobalStudy-wide5008T=0.892C=0.108
1000GenomesSouth AsianSub978T=0.950C=0.050
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.840C=0.160
The Genome Aggregation DatabaseAfricanSub8714T=0.847C=0.153
The Genome Aggregation DatabaseAmericanSub836T=0.900C=0.100
The Genome Aggregation DatabaseEast AsianSub1616T=0.925C=0.075
The Genome Aggregation DatabaseEuropeSub18492T=0.844C=0.156
The Genome Aggregation DatabaseGlobalStudy-wide29960T=0.850C=0.149
The Genome Aggregation DatabaseOtherSub302T=0.850C=0.150
Trans-Omics for Precision MedicineGlobalStudy-wide29118T=0.837C=0.162
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.855C=0.145
PMID Title Author Journal
21314694Genomewide association analysis of symptoms of alcohol dependence in the molecular genetics of schizophrenia (MGS2) control sample.Kendler KSAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs174785370.000755alcohol dependence21314694

eQTL of rs17478537 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs17478537 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr2204445632204445892E067-13287
chr2204450307204450618E067-8561
chr2204501588204502238E06742409
chr2204445632204445892E068-13287
chr2204445632204445892E069-13287
chr2204502294204502673E06943115
chr2204445632204445892E070-13287
chr2204451049204451121E070-8058
chr2204445632204445892E071-13287
chr2204456428204456540E071-2639
chr2204456581204456692E071-2487
chr2204501588204502238E07142409
chr2204502294204502673E07143115
chr2204502697204502826E07143518
chr2204445632204445892E072-13287
chr2204445632204445892E073-13287
chr2204445632204445892E074-13287
chr2204501588204502238E07442409
chr2204502294204502673E07443115
chr2204502697204502826E07443518
chr2204427101204427332E081-31847
chr2204427350204427477E081-31702
chr2204445632204445892E082-13287
chr2204448125204448352E082-10827
chr2204448454204448911E082-10268