rs1752653

Homo sapiens
T>C
None
Check p-value
SNV (Single Nucleotide Variation)
T==0218 (6536/29922,GnomAD)
T==0227 (6619/29116,TOPMED)
T==0137 (687/5008,1000G)
T==0217 (838/3854,ALSPAC)
T==0212 (787/3708,TWINSUK)
chr13:26748640 (GRCh38.p7) (13q12.13)
AD
GWASdb2
1   publication(s)
See rs on genome
47 Enhancers around
61 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 13NC_000013.11:g.26748640T>C
GRCh37.p13 chr 13NC_000013.10:g.27322777T>C

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.261C=0.739
1000GenomesAmericanSub694T=0.110C=0.890
1000GenomesEast AsianSub1008T=0.017C=0.983
1000GenomesEuropeSub1006T=0.203C=0.797
1000GenomesGlobalStudy-wide5008T=0.137C=0.863
1000GenomesSouth AsianSub978T=0.050C=0.950
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.217C=0.783
The Genome Aggregation DatabaseAfricanSub8712T=0.248C=0.752
The Genome Aggregation DatabaseAmericanSub838T=0.100C=0.900
The Genome Aggregation DatabaseEast AsianSub1622T=0.010C=0.990
The Genome Aggregation DatabaseEuropeSub18450T=0.229C=0.770
The Genome Aggregation DatabaseGlobalStudy-wide29922T=0.218C=0.781
The Genome Aggregation DatabaseOtherSub300T=0.120C=0.880
Trans-Omics for Precision MedicineGlobalStudy-wide29116T=0.227C=0.772
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.212C=0.788
PMID Title Author Journal
23953852Genome-wide association studies of maximum number of drinks.Pan YJ Psychiatr Res

P-Value

SNP ID p-value Traits Study
rs17526536.29E-06alcohol consumption23953852

eQTL of rs1752653 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
Chr13:27322777GPR12ENSG00000132975.6T>C8.5134e-15-12145Cerebellum

meQTL of rs1752653 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr132728180027282239E067-40538
chr132729649227296551E068-26226
chr132729649227296551E070-26226
chr132729671727296874E070-25903
chr132733594427336000E07013167
chr132727317527273276E071-49501
chr132729649227296551E071-26226
chr132729649227296551E072-26226
chr132729671727296874E072-25903
chr132729649227296551E074-26226
chr132729671727296874E074-25903
chr132728510827285204E081-37573
chr132728541527285849E081-36928
chr132729114127291191E081-31586
chr132729219027292328E081-30449
chr132729240327292453E081-30324
chr132729254127292636E081-30141
chr132729291727292980E081-29797
chr132729301927293161E081-29616
chr132729325027293301E081-29476
chr132729334927293399E081-29378
chr132729522327295377E081-27400
chr132729649227296551E081-26226
chr132732184427322177E081-600
chr132733594427336000E08113167
chr132733702327337492E08114246
chr132735465127354762E08131874
chr132735493727355017E08132160
chr132736052927360639E08137752
chr132736092127361046E08138144
chr132736109027361274E08138313
chr132736142627361590E08138649
chr132736191427362136E08139137
chr132736218627362449E08139409
chr132736331027363361E08140533
chr132736337627363528E08140599
chr132736359927363765E08140822
chr132729522327295377E082-27400
chr132733629027336334E08213513
chr132733702327337492E08214246
chr132733761527337711E08214838
chr132733773827337778E08214961
chr132733791927337996E08215142
chr132736218627362449E08239409
chr132736337627363528E08240599
chr132736528427365385E08242507
chr132736550927365652E08242732








Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr132733224427332294E0679467
chr132733237827332428E0679601
chr132733267027332974E0679893
chr132733299727333096E06710220
chr132733310727333190E06710330
chr132733335627334666E06710579
chr132733473127334928E06711954
chr132733493727335004E06712160
chr132733507627335161E06712299
chr132733517827335522E06712401
chr132733224427332294E0689467
chr132733237827332428E0689601
chr132733267027332974E0689893
chr132733299727333096E06810220
chr132733310727333190E06810330
chr132733335627334666E06810579
chr132733473127334928E06811954
chr132733493727335004E06812160
chr132733507627335161E06812299
chr132733517827335522E06812401
chr132733335627334666E06910579
chr132733473127334928E06911954
chr132733493727335004E06912160
chr132733507627335161E06912299
chr132733517827335522E06912401
chr132733299727333096E07010220
chr132733310727333190E07010330
chr132733335627334666E07010579
chr132733473127334928E07011954
chr132733493727335004E07012160
chr132733507627335161E07012299
chr132733335627334666E07110579
chr132733473127334928E07111954
chr132733493727335004E07112160
chr132733507627335161E07112299
chr132733267027332974E0729893
chr132733299727333096E07210220
chr132733310727333190E07210330
chr132733335627334666E07210579
chr132733473127334928E07211954
chr132733493727335004E07212160
chr132733507627335161E07212299
chr132733517827335522E07212401
chr132733335627334666E07310579
chr132733473127334928E07311954
chr132733493727335004E07312160
chr132733507627335161E07312299
chr132733517827335522E07312401
chr132733335627334666E07410579
chr132733224427332294E0819467
chr132733237827332428E0819601
chr132733224427332294E0829467
chr132733237827332428E0829601
chr132733267027332974E0829893
chr132733299727333096E08210220
chr132733310727333190E08210330
chr132733335627334666E08210579
chr132733473127334928E08211954
chr132733493727335004E08212160
chr132733507627335161E08212299
chr132733517827335522E08212401