rs17527069

Homo sapiens
T>C
None
Check p-value
SNV (Single Nucleotide Variation)
C=0134 (4029/29948,GnomAD)
C=0119 (3470/29118,TOPMED)
C=0139 (698/5008,1000G)
C=0193 (744/3854,ALSPAC)
C=0184 (684/3708,TWINSUK)
chr10:10235382 (GRCh38.p7) (10p14)
AD
GWASdb2
1   publication(s)
See rs on genome
12 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 10NC_000010.11:g.10235382T>C
GRCh37.p13 chr 10NC_000010.10:g.10277345T>C

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.979C=0.021
1000GenomesAmericanSub694T=0.810C=0.190
1000GenomesEast AsianSub1008T=0.899C=0.101
1000GenomesEuropeSub1006T=0.813C=0.187
1000GenomesGlobalStudy-wide5008T=0.861C=0.139
1000GenomesSouth AsianSub978T=0.750C=0.250
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.807C=0.193
The Genome Aggregation DatabaseAfricanSub8730T=0.963C=0.037
The Genome Aggregation DatabaseAmericanSub836T=0.780C=0.220
The Genome Aggregation DatabaseEast AsianSub1616T=0.903C=0.097
The Genome Aggregation DatabaseEuropeSub18466T=0.822C=0.177
The Genome Aggregation DatabaseGlobalStudy-wide29948T=0.865C=0.134
The Genome Aggregation DatabaseOtherSub300T=0.720C=0.280
Trans-Omics for Precision MedicineGlobalStudy-wide29118T=0.880C=0.119
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.816C=0.184
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs175270690.00051alcohol dependence20201924

eQTL of rs17527069 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs17527069 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr101024973310249810E081-27535
chr101025006010250157E081-27188
chr101025018410250228E081-27117
chr101025025110250532E081-26813
chr101025095810252230E081-25115
chr101025267310252727E081-24618
chr101025298010253020E081-24325
chr101027486010275786E081-1559
chr101027608810276173E081-1172
chr101027642910276479E081-866
chr101031435810314540E08137013
chr101025267310252727E082-24618