rs17536666

Homo sapiens
T>C
None
Check p-value
SNV (Single Nucleotide Variation)
C=0051 (1533/29886,GnomAD)
C=0034 (1017/29118,TOPMED)
C=0028 (138/5008,1000G)
C=0048 (184/3854,ALSPAC)
C=0053 (196/3708,TWINSUK)
chr5:1844201 (GRCh38.p7) (5p15.33)
ND
GWASdb2
1   publication(s)
See rs on genome
32 Enhancers around
15 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 5NC_000005.10:g.1844201T>C
GRCh37.p13 chr 5NC_000005.9:g.1844315T>C

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.998C=0.002
1000GenomesAmericanSub694T=0.900C=0.100
1000GenomesEast AsianSub1008T=1.000C=0.000
1000GenomesEuropeSub1006T=0.958C=0.042
1000GenomesGlobalStudy-wide5008T=0.972C=0.028
1000GenomesSouth AsianSub978T=0.970C=0.030
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.952C=0.048
The Genome Aggregation DatabaseAfricanSub8688T=0.989C=0.011
The Genome Aggregation DatabaseAmericanSub834T=0.880C=0.120
The Genome Aggregation DatabaseEast AsianSub1620T=1.000C=0.000
The Genome Aggregation DatabaseEuropeSub18442T=0.927C=0.072
The Genome Aggregation DatabaseGlobalStudy-wide29886T=0.948C=0.051
The Genome Aggregation DatabaseOtherSub302T=0.990C=0.010
Trans-Omics for Precision MedicineGlobalStudy-wide29118T=0.965C=0.034
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.947C=0.053
PMID Title Author Journal
17158188Novel genes identified in a high-density genome wide association study for nicotine dependence.Bierut LJHum Mol Genet

P-Value

SNP ID p-value Traits Study
rs175366660.000966nicotine dependence17158188

eQTL of rs17536666 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs17536666 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr517973461797422E067-46893
chr517982171798312E067-46003
chr517983721798431E067-45884
chr518612991861441E06716984
chr518615931861656E06717278
chr518082691808319E068-35996
chr518085161808945E068-35370
chr518612991861441E06816984
chr518615931861656E06817278
chr518612991861441E06916984
chr518615931861656E06917278
chr517982171798312E070-46003
chr517983721798431E070-45884
chr518027131802753E070-41562
chr518037451803845E070-40470
chr518027131802753E071-41562
chr518612991861441E07116984
chr518615931861656E07117278
chr518896591890173E07145344
chr517973461797422E072-46893
chr517982171798312E072-46003
chr517983721798431E072-45884
chr518612991861441E07216984
chr518615931861656E07217278
chr517973461797422E073-46893
chr517982171798312E073-46003
chr517983721798431E073-45884
chr518612991861441E07416984
chr518615931861656E07417278
chr518896591890173E07445344
chr518505741850643E0816259
chr517973461797422E082-46893










Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr517992421802253E067-42062
chr517992421802253E068-42062
chr518513261851930E0687011
chr517992421802253E069-42062
chr517992421802253E070-42062
chr518512571851307E0706942
chr518513261851930E0707011
chr517992421802253E071-42062
chr517992421802253E072-42062
chr517992421802253E073-42062
chr517992421802253E074-42062
chr517992421802253E081-42062
chr517992421802253E082-42062
chr518513261851930E0827011
chr518868691887927E08242554