rs17536732

Homo sapiens
G>T
FSTL5 : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
T=0046 (1378/29768,GnomAD)
T=0040 (1192/29118,TOPMED)
T=0024 (122/5008,1000G)
T=0076 (293/3854,ALSPAC)
T=0080 (297/3708,TWINSUK)
chr4:161903214 (GRCh38.p7) (4q32.2)
AD
GWASCatalog
1   publication(s)
See rs on genome
16 Enhancers around
1 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 4NC_000004.12:g.161903214G>T
GRCh37.p13 chr 4NC_000004.11:g.162824366G>T

Gene: FSTL5, follistatin like 5(minus strand)

Molecule type Change Amino acid[Codon] SO Term
FSTL5 transcript variant 2NM_001128427.2:c.N/AIntron Variant
FSTL5 transcript variant 3NM_001128428.2:c.N/AIntron Variant
FSTL5 transcript variant 1NM_020116.4:c.N/AIntron Variant
FSTL5 transcript variant X1XM_011532126.1:c.N/AIntron Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.994T=0.006
1000GenomesAmericanSub694G=0.980T=0.020
1000GenomesEast AsianSub1008G=1.000T=0.000
1000GenomesEuropeSub1006G=0.927T=0.073
1000GenomesGlobalStudy-wide5008G=0.976T=0.024
1000GenomesSouth AsianSub978G=0.970T=0.030
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=0.924T=0.076
The Genome Aggregation DatabaseAfricanSub8674G=0.984T=0.016
The Genome Aggregation DatabaseAmericanSub806G=0.960T=0.040
The Genome Aggregation DatabaseEast AsianSub1614G=0.999T=0.001
The Genome Aggregation DatabaseEuropeSub18372G=0.934T=0.065
The Genome Aggregation DatabaseGlobalStudy-wide29768G=0.953T=0.046
The Genome Aggregation DatabaseOtherSub302G=0.970T=0.030
Trans-Omics for Precision MedicineGlobalStudy-wide29118G=0.959T=0.040
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.920T=0.080
PMID Title Author Journal
28990359Ancestry-specific and sex-specific risk alleles identified in a genome-wide gene-by-alcohol dependence interaction study of risky sexual behaviors.Polimanti RAm J Med Genet B Neuropsychiatr Genet

P-Value

SNP ID p-value Traits Study
rs175367324E-08alcohol dependence28990359

eQTL of rs17536732 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs17536732 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr4162851166162851415E06826800
chr4162851166162851415E06926800
chr4162852310162852508E06927944
chr4162802887162802937E070-21429
chr4162804397162804447E070-19919
chr4162804557162804623E070-19743
chr4162814147162814303E072-10063
chr4162851166162851415E07226800
chr4162802887162802937E074-21429
chr4162851166162851415E07426800
chr4162852310162852508E07427944
chr4162828026162828464E0823660
chr4162828925162828988E0824559
chr4162841210162841339E08216844
chr4162841512162841633E08217146
chr4162841997162842061E08217631






Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr4162847692162847922E06823326