SNP Detail Info-rs17541873

Organism: Homo sapiens

Alleles: G>A

Gene : Feature

None

p-value: Check p-value

Variation Type: SNV (Single Nucleotide Variation)

Frequency:

A=0094 (2830/29966,GnomAD)
A=0093 (2714/29118,TOPMED)
A=0102 (509/5008,1000G)
A=0108 (418/3854,ALSPAC)
A=0113 (420/3708,TWINSUK)

Position: chr6:86291852 (GRCh38.p7) (6q14.3)

Phenotype: AD

Dataset:

GWASdb2

Publications: 1 publication(s)

Genomic View: See rs on genome

Enhancer: 0 Enhancer around

Promoter: 0 Promoter around

Sequence Name	Change(s)
GRCh38.p7 chr 6	NC_000006.12:g.86291852G>A
GRCh37.p13 chr 6	NC_000006.11:g.87001570G>A

Study	Population	Group	Sample #	Ref Allele	Alt Allele
1000Genomes	African	Sub	1322	G=0.943	A=0.057
1000Genomes	American	Sub	694	G=0.940	A=0.060
1000Genomes	East Asian	Sub	1008	G=0.938	A=0.062
1000Genomes	Europe	Sub	1006	G=0.865	A=0.135
1000Genomes	Global	Study-wide	5008	G=0.898	A=0.102
1000Genomes	South Asian	Sub	978	G=0.810	A=0.190
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	G=0.892	A=0.108
The Genome Aggregation Database	African	Sub	8726	G=0.937	A=0.063
The Genome Aggregation Database	American	Sub	838	G=0.920	A=0.080
The Genome Aggregation Database	East Asian	Sub	1612	G=0.971	A=0.029
The Genome Aggregation Database	Europe	Sub	18488	G=0.885	A=0.114
The Genome Aggregation Database	Global	Study-wide	29966	G=0.905	A=0.094
The Genome Aggregation Database	Other	Sub	302	G=0.820	A=0.180
Trans-Omics for Precision Medicine	Global	Study-wide	29118	G=0.906	A=0.093
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	G=0.887	A=0.113

PMID	Title	Author	Journal
24277619	ALDH2 is associated to alcohol dependence and is the major genetic determinant of "daily maximum drinks" in a GWAS study of an isolated rural Chinese sample.	Quillen EE	Am J Med Genet B Neuropsychiatr Genet

SNP ID	p-value	Traits	Study
rs17541873	0.000431	alcohol dependence	24277619

Position (v37)	eGene	GeneID	Variant	p-value	TSS	Tissue
There is no eQTL annotation for this SNP

Probe ID	Position	Gene	beta	p-value
There is no meQTL annotation for this SNP

rs17541873