rs1757321

Homo sapiens
C>T
DAB2IP : Intron Variant
LOC107987016 : Non Coding Transcript Variant
Check p-value
SNV (Single Nucleotide Variation)
T=0281 (8426/29936,GnomAD)
T=0309 (9004/29118,TOPMED)
T=0202 (1014/5008,1000G)
T=0317 (1220/3854,ALSPAC)
T=0318 (1179/3708,TWINSUK)
chr9:121569480 (GRCh38.p7) (9q33.2)
AD
GWASdb2
1   publication(s)
See rs on genome
8 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 9NC_000009.12:g.121569480C>T
GRCh37.p13 chr 9NC_000009.11:g.124331759C>T

Gene: DAB2IP, DAB2 interacting protein(plus strand)

Molecule type Change Amino acid[Codon] SO Term
DAB2IP transcript variant 1NM_032552.3:c.N/AIntron Variant
DAB2IP transcript variant 2NM_138709.2:c.N/AGenic Upstream Transcript Variant
DAB2IP transcript variant X7XM_005251721.1:c.N/AIntron Variant
DAB2IP transcript variant X5XM_005251719.4:c.N/AGenic Upstream Transcript Variant
DAB2IP transcript variant X9XM_005251724.4:c.N/AGenic Upstream Transcript Variant
DAB2IP transcript variant X1XM_011518264.2:c.N/AGenic Upstream Transcript Variant
DAB2IP transcript variant X2XM_011518265.2:c.N/AGenic Upstream Transcript Variant
DAB2IP transcript variant X3XM_011518266.2:c.N/AGenic Upstream Transcript Variant
DAB2IP transcript variant X4XM_011518267.2:c.N/AGenic Upstream Transcript Variant
DAB2IP transcript variant X10XM_011518270.2:c.N/AGenic Upstream Transcript Variant
DAB2IP transcript variant X12XM_011518271.2:c.N/AGenic Upstream Transcript Variant
DAB2IP transcript variant X6XM_017014298.1:c.N/AGenic Upstream Transcript Variant
DAB2IP transcript variant X8XM_017014299.1:c.N/AGenic Upstream Transcript Variant
DAB2IP transcript variant X11XM_017014300.1:c.N/AGenic Upstream Transcript Variant

Gene: LOC107987016, uncharacterized LOC107987016(minus strand)

Molecule type Change Amino acid[Codon] SO Term
LOC107987016 transcriptXR_001746560.1:n....XR_001746560.1:n.85G>AG>ANon Coding Transcript Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.650T=0.350
1000GenomesAmericanSub694C=0.800T=0.200
1000GenomesEast AsianSub1008C=0.999T=0.001
1000GenomesEuropeSub1006C=0.706T=0.294
1000GenomesGlobalStudy-wide5008C=0.798T=0.202
1000GenomesSouth AsianSub978C=0.880T=0.120
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.683T=0.317
The Genome Aggregation DatabaseAfricanSub8708C=0.655T=0.345
The Genome Aggregation DatabaseAmericanSub838C=0.840T=0.160
The Genome Aggregation DatabaseEast AsianSub1622C=0.999T=0.001
The Genome Aggregation DatabaseEuropeSub18470C=0.718T=0.281
The Genome Aggregation DatabaseGlobalStudy-wide29936C=0.718T=0.281
The Genome Aggregation DatabaseOtherSub298C=0.700T=0.300
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.690T=0.309
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.682T=0.318
PMID Title Author Journal
21314694Genomewide association analysis of symptoms of alcohol dependence in the molecular genetics of schizophrenia (MGS2) control sample.Kendler KSAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs17573210.000156alcohol dependence21314694

eQTL of rs1757321 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs1757321 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr9124308004124308815E067-22944
chr9124326500124326603E067-5156
chr9124326686124326756E067-5003
chr9124326778124326830E067-4929
chr9124326924124326997E067-4762
chr9124327013124327209E067-4550
chr9124328720124331565E067-194
chr9124331665124331825E0670
chr9124336134124336241E0674375
chr9124336283124336375E0674524
chr9124338843124338904E0677084
chr9124338929124338979E0677170
chr9124338987124339267E0677228
chr9124339358124339816E0677599
chr9124339932124340162E0678173
chr9124340230124340280E0678471
chr9124343477124343527E06711718
chr9124343528124343578E06711769
chr9124343600124343650E06711841
chr9124343729124343799E06711970
chr9124343908124344728E06712149
chr9124344731124344793E06712972
chr9124347237124347338E06715478
chr9124363255124363305E06731496
chr9124365676124365735E06733917
chr9124365949124366009E06734190
chr9124366067124366214E06734308
chr9124369778124370680E06738019
chr9124370691124370971E06738932
chr9124371576124371983E06739817
chr9124371987124373218E06740228
chr9124319702124321219E068-10540
chr9124326778124326830E068-4929
chr9124326924124326997E068-4762
chr9124327013124327209E068-4550
chr9124328608124328669E068-3090
chr9124328720124331565E068-194
chr9124336748124336837E0684989
chr9124336845124336918E0685086
chr9124337191124337298E0685432
chr9124343207124343299E06811448
chr9124343477124343527E06811718
chr9124343528124343578E06811769
chr9124343600124343650E06811841
chr9124343729124343799E06811970
chr9124344731124344793E06812972
chr9124344907124345289E06813148
chr9124346835124346967E06815076
chr9124362923124363211E06831164
chr9124363255124363305E06831496
chr9124363335124363904E06831576
chr9124364038124364260E06832279
chr9124365385124365655E06833626
chr9124365676124365735E06833917
chr9124365949124366009E06834190
chr9124366067124366214E06834308
chr9124367009124367224E06835250
chr9124369626124369754E06837867
chr9124369778124370680E06838019
chr9124370691124370971E06838932
chr9124371576124371983E06839817
chr9124371987124373218E06840228
chr9124374763124375670E06843004
chr9124375711124376057E06843952
chr9124376098124376164E06844339
chr9124379048124379141E06847289
chr9124300474124300866E069-30893
chr9124313657124313787E069-17972
chr9124318307124319360E069-12399
chr9124319702124321219E069-10540
chr9124337191124337298E0695432
chr9124337394124337502E0695635
chr9124343477124343527E06911718
chr9124343528124343578E06911769
chr9124343600124343650E06911841
chr9124343729124343799E06911970
chr9124344731124344793E06912972
chr9124363335124363904E06931576
chr9124367009124367224E06935250
chr9124369778124370680E06938019
chr9124371987124373218E06940228
chr9124374763124375670E06943004
chr9124375711124376057E06943952
chr9124328720124331565E070-194
chr9124343908124344728E07012149
chr9124344731124344793E07012972
chr9124291051124292528E071-39231
chr9124318307124319360E071-12399
chr9124319702124321219E071-10540
chr9124328329124328522E071-3237
chr9124328608124328669E071-3090
chr9124331665124331825E0710
chr9124336748124336837E0714989
chr9124336845124336918E0715086
chr9124337191124337298E0715432
chr9124337394124337502E0715635
chr9124337519124337581E0715760
chr9124337582124337772E0715823
chr9124343207124343299E07111448
chr9124343477124343527E07111718
chr9124343528124343578E07111769
chr9124343600124343650E07111841
chr9124343729124343799E07111970
chr9124344731124344793E07112972
chr9124344907124345289E07113148
chr9124363335124363904E07131576
chr9124364038124364260E07132279
chr9124364326124364376E07132567
chr9124364564124364626E07132805
chr9124365949124366009E07134190
chr9124366067124366214E07134308
chr9124366501124366982E07134742
chr9124367009124367224E07135250
chr9124369778124370680E07138019
chr9124370691124370971E07138932
chr9124371439124371523E07139680
chr9124371576124371983E07139817
chr9124371987124373218E07140228
chr9124374763124375670E07143004
chr9124375711124376057E07143952
chr9124376098124376164E07144339
chr9124376204124376268E07144445
chr9124378519124378665E07146760
chr9124378757124378817E07146998
chr9124378879124378940E07147120
chr9124307628124307981E072-23778
chr9124318307124319360E072-12399
chr9124319702124321219E072-10540
chr9124328329124328522E072-3237
chr9124328608124328669E072-3090
chr9124331665124331825E0720
chr9124337191124337298E0725432
chr9124337394124337502E0725635
chr9124337519124337581E0725760
chr9124337582124337772E0725823
chr9124337774124337929E0726015
chr9124337933124337992E0726174
chr9124339358124339816E0727599
chr9124339932124340162E0728173
chr9124343477124343527E07211718
chr9124343528124343578E07211769
chr9124343600124343650E07211841
chr9124343729124343799E07211970
chr9124343908124344728E07212149
chr9124344731124344793E07212972
chr9124344907124345289E07213148
chr9124362923124363211E07231164
chr9124363255124363305E07231496
chr9124366501124366982E07234742
chr9124367009124367224E07235250
chr9124369336124369431E07237577
chr9124369626124369754E07237867
chr9124370691124370971E07238932
chr9124371576124371983E07239817
chr9124371987124373218E07240228
chr9124374763124375670E07243004
chr9124375711124376057E07243952
chr9124376098124376164E07244339
chr9124376204124376268E07244445
chr9124378383124378441E07246624
chr9124378519124378665E07246760
chr9124378757124378817E07246998
chr9124378879124378940E07247120
chr9124379048124379141E07247289
chr9124379188124379311E07247429
chr9124289889124289965E073-41794
chr9124300474124300866E073-30893
chr9124307628124307981E073-23778
chr9124319702124321219E073-10540
chr9124326778124326830E073-4929
chr9124326924124326997E073-4762
chr9124327013124327209E073-4550
chr9124327211124327520E073-4239
chr9124327578124327688E073-4071
chr9124328329124328522E073-3237
chr9124328608124328669E073-3090
chr9124331665124331825E0730
chr9124336511124336621E0734752
chr9124336748124336837E0734989
chr9124336845124336918E0735086
chr9124337191124337298E0735432
chr9124337394124337502E0735635
chr9124337519124337581E0735760
chr9124337582124337772E0735823
chr9124338843124338904E0737084
chr9124338929124338979E0737170
chr9124338987124339267E0737228
chr9124339358124339816E0737599
chr9124339932124340162E0738173
chr9124343207124343299E07311448
chr9124343477124343527E07311718
chr9124343528124343578E07311769
chr9124343600124343650E07311841
chr9124343729124343799E07311970
chr9124343908124344728E07312149
chr9124344731124344793E07312972
chr9124344907124345289E07313148
chr9124362923124363211E07331164
chr9124363255124363305E07331496
chr9124363335124363904E07331576
chr9124365676124365735E07333917
chr9124365949124366009E07334190
chr9124366067124366214E07334308
chr9124366501124366982E07334742
chr9124367009124367224E07335250
chr9124369778124370680E07338019
chr9124371987124373218E07340228
chr9124374763124375670E07343004
chr9124375711124376057E07343952
chr9124376098124376164E07344339
chr9124308004124308815E074-22944
chr9124319702124321219E074-10540
chr9124328720124331565E074-194
chr9124336134124336241E0744375
chr9124336283124336375E0744524
chr9124336424124336508E0744665
chr9124336511124336621E0744752
chr9124336748124336837E0744989
chr9124336845124336918E0745086
chr9124337191124337298E0745432
chr9124337394124337502E0745635
chr9124337519124337581E0745760
chr9124337582124337772E0745823
chr9124337774124337929E0746015
chr9124338987124339267E0747228
chr9124343477124343527E07411718
chr9124343528124343578E07411769
chr9124343600124343650E07411841
chr9124343729124343799E07411970
chr9124344731124344793E07412972
chr9124344907124345289E07413148
chr9124345536124345583E07413777
chr9124345596124345682E07413837
chr9124347237124347338E07415478
chr9124362923124363211E07431164
chr9124363255124363305E07431496
chr9124363335124363904E07431576
chr9124366067124366214E07434308
chr9124366501124366982E07434742
chr9124369336124369431E07437577
chr9124369626124369754E07437867
chr9124369778124370680E07438019
chr9124371987124373218E07440228
chr9124374763124375670E07443004
chr9124375711124376057E07443952
chr9124307628124307981E081-23778
chr9124308004124308815E081-22944
chr9124328720124331565E081-194
chr9124343908124344728E08112149
chr9124344731124344793E08112972
chr9124369778124370680E08138019
chr9124328720124331565E082-194
chr9124343908124344728E08212149
chr9124370691124370971E08238932










Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr9124359916124362866E06728157
chr9124359916124362866E06828157
chr9124359916124362866E06928157
chr9124359916124362866E07128157
chr9124359916124362866E07228157
chr9124359916124362866E07328157
chr9124359916124362866E07428157
chr9124359916124362866E08228157