rs1757939

Homo sapiens
T>C
None
Check p-value
SNV (Single Nucleotide Variation)
T==0406 (11840/29118,TOPMED)
T==0409 (2049/5008,1000G)
T==0420 (1617/3854,ALSPAC)
T==0410 (1522/3708,TWINSUK)
chr4:129225021 (GRCh38.p7) (4q28.2)
CD
GWASdb2
1   publication(s)
See rs on genome
2 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 4NC_000004.12:g.129225021T>C
GRCh37.p13 chr 4NC_000004.11:g.130146176T>C

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.408C=0.592
1000GenomesAmericanSub694T=0.520C=0.480
1000GenomesEast AsianSub1008T=0.377C=0.623
1000GenomesEuropeSub1006T=0.430C=0.570
1000GenomesGlobalStudy-wide5008T=0.409C=0.591
1000GenomesSouth AsianSub978T=0.340C=0.660
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.420C=0.580
Trans-Omics for Precision MedicineGlobalStudy-wide29118T=0.406C=0.593
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.410C=0.590
PMID Title Author Journal
23958962Genome-wide association study of cocaine dependence and related traits: FAM53B identified as a risk gene.Gelernter JMol Psychiatry

P-Value

SNP ID p-value Traits Study
rs17579392.9E-05cocaine dependence23958962

eQTL of rs1757939 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs1757939 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr4130153593130153689E0707417
chr4130187925130187994E07041749