rs17582647

Homo sapiens
T>C
None
Check p-value
SNV (Single Nucleotide Variation)
C=0126 (3771/29924,GnomAD)
C=0122 (3557/29118,TOPMED)
C=0092 (463/5008,1000G)
C=0145 (558/3854,ALSPAC)
C=0142 (527/3708,TWINSUK)
chr8:81372178 (GRCh38.p7) (8q21.13)
ND
GWASdb2
1   publication(s)
See rs on genome
116 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 8NC_000008.11:g.81372178T>C
GRCh37.p13 chr 8NC_000008.10:g.82284413T>C

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.910C=0.090
1000GenomesAmericanSub694T=0.920C=0.080
1000GenomesEast AsianSub1008T=0.999C=0.001
1000GenomesEuropeSub1006T=0.850C=0.150
1000GenomesGlobalStudy-wide5008T=0.908C=0.092
1000GenomesSouth AsianSub978T=0.860C=0.140
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.855C=0.145
The Genome Aggregation DatabaseAfricanSub8714T=0.896C=0.104
The Genome Aggregation DatabaseAmericanSub838T=0.920C=0.080
The Genome Aggregation DatabaseEast AsianSub1612T=0.999C=0.001
The Genome Aggregation DatabaseEuropeSub18458T=0.852C=0.147
The Genome Aggregation DatabaseGlobalStudy-wide29924T=0.874C=0.126
The Genome Aggregation DatabaseOtherSub302T=0.770C=0.230
Trans-Omics for Precision MedicineGlobalStudy-wide29118T=0.877C=0.122
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.858C=0.142
PMID Title Author Journal
17158188Novel genes identified in a high-density genome wide association study for nicotine dependence.Bierut LJHum Mol Genet

P-Value

SNP ID p-value Traits Study
rs175826470.000276nicotine dependence17158188

eQTL of rs17582647 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs17582647 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr88224700182247223E067-37190
chr88224731582247649E067-36764
chr88224773882247890E067-36523
chr88227654882277260E067-7153
chr88228858282288707E0674169
chr88228882182289160E0674408
chr88224680782246868E068-37545
chr88224700182247223E068-37190
chr88225217382252502E068-31911
chr88227654882277260E068-7153
chr88227756682277694E068-6719
chr88227794482277994E068-6419
chr88228228682282481E068-1932
chr88228252982282585E068-1828
chr88228261082282660E068-1753
chr88228501382285127E068600
chr88228523282285629E068819
chr88228659882286685E0682185
chr88228710682287355E0682693
chr88228858282288707E0684169
chr88228882182289160E0684408
chr88231364482313848E06829231
chr88224700182247223E069-37190
chr88224731582247649E069-36764
chr88224773882247890E069-36523
chr88224792482248142E069-36271
chr88225011682250205E069-34208
chr88225031482251204E069-33209
chr88227654882277260E069-7153
chr88227756682277694E069-6719
chr88227794482277994E069-6419
chr88228858282288707E0694169
chr88228882182289160E0694408
chr88231253382312658E06928120
chr88231275882313343E06928345
chr88231364482313848E06929231
chr88224680782246868E070-37545
chr88224700182247223E070-37190
chr88224731582247649E070-36764
chr88224773882247890E070-36523
chr88224820882248391E070-36022
chr88224952782250021E070-34392
chr88225011682250205E070-34208
chr88225031482251204E070-33209
chr88226296082263514E070-20899
chr88226354782263603E070-20810
chr88227654882277260E070-7153
chr88227756682277694E070-6719
chr88227794482277994E070-6419
chr88227810282278142E070-6271
chr88228110882281158E070-3255
chr88228129582281454E070-2959
chr88228147682281508E070-2905
chr88228166082282231E070-2182
chr88228228682282481E070-1932
chr88228252982282585E070-1828
chr88228261082282660E070-1753
chr88228303182283081E070-1332
chr88228523282285629E070819
chr88228615982286213E0701746
chr88228858282288707E0704169
chr88228882182289160E0704408
chr88224700182247223E071-37190
chr88224731582247649E071-36764
chr88224773882247890E071-36523
chr88224792482248142E071-36271
chr88227622882276446E071-7967
chr88227654882277260E071-7153
chr88227756682277694E071-6719
chr88228261082282660E071-1753
chr88228303182283081E071-1332
chr88228315482283685E071-728
chr88228882182289160E0714408
chr88231253382312658E07128120
chr88231275882313343E07128345
chr88231364482313848E07129231
chr88224700182247223E072-37190
chr88224731582247649E072-36764
chr88224773882247890E072-36523
chr88224792482248142E072-36271
chr88224820882248391E072-36022
chr88227654882277260E072-7153
chr88228858282288707E0724169
chr88228882182289160E0724408
chr88231364482313848E07229231
chr88231424282314305E07229829
chr88227654882277260E073-7153
chr88228303182283081E073-1332
chr88228315482283685E073-728
chr88228882182289160E0734408
chr88224680782246868E074-37545
chr88224700182247223E074-37190
chr88224731582247649E074-36764
chr88224820882248391E074-36022
chr88225011682250205E074-34208
chr88225031482251204E074-33209
chr88226284382262915E074-21498
chr88226296082263514E074-20899
chr88227654882277260E074-7153
chr88227756682277694E074-6719
chr88228858282288707E0744169
chr88228882182289160E0744408
chr88231275882313343E07428345
chr88231364482313848E07429231
chr88224680782246868E081-37545
chr88224700182247223E081-37190
chr88224731582247649E081-36764
chr88228129582281454E081-2959
chr88228147682281508E081-2905
chr88228166082282231E081-2182
chr88228228682282481E081-1932
chr88225217382252502E082-31911
chr88225253582252631E082-31782
chr88228129582281454E082-2959
chr88228147682281508E082-2905
chr88228166082282231E082-2182