rs17602660

Homo sapiens
A>T
DGKB : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
T=0025 (767/29894,GnomAD)
T=0028 (814/29118,TOPMED)
T=0016 (82/5008,1000G)
T=0044 (170/3854,ALSPAC)
T=0046 (170/3708,TWINSUK)
chr7:14606660 (GRCh38.p7) (7p21.2)
AD
GWASdb2
1   publication(s)
See rs on genome
0 Enhancer around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 7NC_000007.14:g.14606660A>T
GRCh37.p13 chr 7NC_000007.13:g.14646285A>T
DGKB RefSeqGeneNG_029494.1:g.239791T>A

Gene: DGKB, diacylglycerol kinase beta(minus strand)

Molecule type Change Amino acid[Codon] SO Term
DGKB transcript variant 1NM_004080.2:c.N/AIntron Variant
DGKB transcript variant 2NM_145695.2:c.N/AIntron Variant
DGKB transcript variant X2XM_005249628.2:c.N/AIntron Variant
DGKB transcript variant X5XM_005249629.2:c.N/AIntron Variant
DGKB transcript variant X8XM_005249630.2:c.N/AIntron Variant
DGKB transcript variant X15XM_005249631.3:c.N/AIntron Variant
DGKB transcript variant X1XM_011515153.2:c.N/AIntron Variant
DGKB transcript variant X1XM_011515154.2:c.N/AIntron Variant
DGKB transcript variant X10XM_011515156.2:c.N/AIntron Variant
DGKB transcript variant X13XM_011515157.2:c.N/AIntron Variant
DGKB transcript variant X16XM_011515158.2:c.N/AIntron Variant
DGKB transcript variant X4XM_017011783.1:c.N/AIntron Variant
DGKB transcript variant X6XM_017011784.1:c.N/AIntron Variant
DGKB transcript variant X7XM_017011785.1:c.N/AIntron Variant
DGKB transcript variant X9XM_017011786.1:c.N/AIntron Variant
DGKB transcript variant X11XM_017011787.1:c.N/AIntron Variant
DGKB transcript variant X12XM_017011788.1:c.N/AIntron Variant
DGKB transcript variant X14XM_017011789.1:c.N/AIntron Variant
DGKB transcript variant X2XM_017011790.1:c.N/AIntron Variant
DGKB transcript variant X3XM_017011791.1:c.N/AIntron Variant
DGKB transcript variant X19XM_017011792.1:c.N/AIntron Variant
DGKB transcript variant X5XR_001744571.1:n.N/AIntron Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322A=0.999T=0.001
1000GenomesAmericanSub694A=0.990T=0.010
1000GenomesEast AsianSub1008A=1.000T=0.000
1000GenomesEuropeSub1006A=0.960T=0.040
1000GenomesGlobalStudy-wide5008A=0.984T=0.016
1000GenomesSouth AsianSub978A=0.970T=0.030
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854A=0.956T=0.044
The Genome Aggregation DatabaseAfricanSub8722A=0.992T=0.008
The Genome Aggregation DatabaseAmericanSub834A=0.990T=0.010
The Genome Aggregation DatabaseEast AsianSub1606A=1.000T=0.000
The Genome Aggregation DatabaseEuropeSub18430A=0.962T=0.037
The Genome Aggregation DatabaseGlobalStudy-wide29894A=0.974T=0.025
The Genome Aggregation DatabaseOtherSub302A=0.990T=0.010
Trans-Omics for Precision MedicineGlobalStudy-wide29118A=0.972T=0.028
UK 10K study - TwinsTWIN COHORTStudy-wide3708A=0.954T=0.046
PMID Title Author Journal
21314694Genomewide association analysis of symptoms of alcohol dependence in the molecular genetics of schizophrenia (MGS2) control sample.Kendler KSAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs176026600.000326alcohol dependence21314694

eQTL of rs17602660 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs17602660 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.