SNP Detail Info-rs1760803

Organism: Homo sapiens

Alleles: A>T

Gene : Feature

None

p-value: Check p-value

Variation Type: SNV (Single Nucleotide Variation)

Frequency:

A==0417 (12141/29118,TOPMED)
T=0488 (2442/5008,1000G)
A==0469 (1806/3854,ALSPAC)
A==0458 (1699/3708,TWINSUK)

Position: chr1:154285418 (GRCh38.p7) (1q21.3)

Phenotype: ND

Dataset:

GWASCatalog

Publications: 1 publication(s)

Genomic View: See rs on genome

Enhancer: 20 Enhancers around

Promoter: 19 Promoters around

Sequence Name	Change(s)
GRCh38.p7 chr 1	NC_000001.11:g.154285418A>T
GRCh37.p13 chr 1	NC_000001.10:g.154257894A>T

Study	Population	Group	Sample #	Ref Allele	Alt Allele
1000Genomes	African	Sub	1322	A=0.343	T=0.657
1000Genomes	American	Sub	694	A=0.650	T=0.350
1000Genomes	East Asian	Sub	1008	A=0.525	T=0.475
1000Genomes	Europe	Sub	1006	A=0.449	T=0.551
1000Genomes	Global	Study-wide	5008	A=0.512	T=0.488
1000Genomes	South Asian	Sub	978	A=0.700	T=0.300
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	A=0.469	T=0.531
Trans-Omics for Precision Medicine	Global	Study-wide	29118	A=0.417	T=0.583
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	A=0.458	T=0.542

PMID	Title	Author	Journal
28440896	Genome-wide meta-analysis identifies a novel susceptibility signal at CACNA2D3 for nicotine dependence.	Yin X	Am J Med Genet B Neuropsychiatr Genet

SNP ID	p-value	Traits	Study
rs1760803	4E-06	nicotine dependence	28440896

Position (v37)	eGene	GeneID	Variant	p-value	TSS	Tissue
There is no eQTL annotation for this SNP

Probe ID	Position	Gene	beta	p-value
There is no meQTL annotation for this SNP

Chromosome	Start	End	Region	Distance ( -/+ : Up/Downstream )
chr1	154296660	154296754	E067	38766
chr1	154307195	154307856	E067	49301
chr1	154277412	154277934	E068	19518
chr1	154306805	154306865	E068	48911
chr1	154306874	154307180	E068	48980
chr1	154307195	154307856	E068	49301
chr1	154307195	154307856	E069	49301
chr1	154246419	154246476	E070	-11418
chr1	154306805	154306865	E071	48911
chr1	154306874	154307180	E071	48980
chr1	154307195	154307856	E071	49301
chr1	154306874	154307180	E072	48980
chr1	154307195	154307856	E072	49301
chr1	154303294	154303434	E073	45400
chr1	154307195	154307856	E073	49301
chr1	154306805	154306865	E074	48911
chr1	154306874	154307180	E074	48980
chr1	154307195	154307856	E074	49301
chr1	154244110	154244164	E081	-13730
chr1	154244261	154244356	E081	-13538

Chromosome	Start	End	Region	Distance(-/+:Up/Downstream)
chr1	154244441	154245596	E067	-12298
chr1	154296837	154300496	E067	38943
chr1	154244441	154245596	E068	-12298
chr1	154296837	154300496	E068	38943
chr1	154244441	154245596	E069	-12298
chr1	154296837	154300496	E069	38943
chr1	154244441	154245596	E070	-12298
chr1	154296837	154300496	E070	38943
chr1	154244441	154245596	E071	-12298
chr1	154296837	154300496	E071	38943
chr1	154244441	154245596	E072	-12298
chr1	154296837	154300496	E072	38943
chr1	154244441	154245596	E073	-12298
chr1	154296837	154300496	E073	38943
chr1	154244441	154245596	E074	-12298
chr1	154296837	154300496	E074	38943
chr1	154244441	154245596	E081	-12298
chr1	154244441	154245596	E082	-12298
chr1	154296837	154300496	E082	38943

rs1760803