rs17616845

Homo sapiens
T>C
None
Check p-value
SNV (Single Nucleotide Variation)
C=0150 (4506/29948,GnomAD)
C=0134 (3907/29118,TOPMED)
C=0151 (758/5008,1000G)
C=0227 (876/3854,ALSPAC)
C=0214 (793/3708,TWINSUK)
chr7:12741918 (GRCh38.p7) (7p21.3)
AD
GWASdb2
1   publication(s)
See rs on genome
65 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 7NC_000007.14:g.12741918T>C
GRCh37.p13 chr 7NC_000007.13:g.12781543T>C

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.940C=0.060
1000GenomesAmericanSub694T=0.840C=0.160
1000GenomesEast AsianSub1008T=0.908C=0.092
1000GenomesEuropeSub1006T=0.770C=0.230
1000GenomesGlobalStudy-wide5008T=0.849C=0.151
1000GenomesSouth AsianSub978T=0.750C=0.250
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.773C=0.227
The Genome Aggregation DatabaseAfricanSub8718T=0.936C=0.064
The Genome Aggregation DatabaseAmericanSub832T=0.890C=0.110
The Genome Aggregation DatabaseEast AsianSub1618T=0.913C=0.087
The Genome Aggregation DatabaseEuropeSub18478T=0.802C=0.198
The Genome Aggregation DatabaseGlobalStudy-wide29948T=0.849C=0.150
The Genome Aggregation DatabaseOtherSub302T=0.820C=0.180
Trans-Omics for Precision MedicineGlobalStudy-wide29118T=0.865C=0.134
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.786C=0.214
PMID Title Author Journal
23089632A genome-wide association study of alcohol-dependence symptom counts in extended pedigrees identifies C15orf53.Wang JCMol Psychiatry

P-Value

SNP ID p-value Traits Study
rs176168458.49E-08alcohol dependence23089632

eQTL of rs17616845 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs17616845 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr71275596012756411E067-25132
chr71275645612756688E067-24855
chr71276876712769145E067-12398
chr71277083112771292E067-10251
chr71277138912771478E067-10065
chr71275596012756411E068-25132
chr71275645612756688E068-24855
chr71275676212756908E068-24635
chr71275853612758619E068-22924
chr71275881412760064E068-21479
chr71276876712769145E068-12398
chr71275596012756411E069-25132
chr71276919012770203E069-11340
chr71277021912770528E069-11015
chr71280358512804303E06922042
chr71280434712804806E06922804
chr71275496712755949E070-25594
chr71275596012756411E070-25132
chr71275645612756688E070-24855
chr71275676212756908E070-24635
chr71276758612767695E070-13848
chr71276774012768108E070-13435
chr71276854612768617E070-12926
chr71276876712769145E070-12398
chr71280358512804303E07022042
chr71280434712804806E07022804
chr71280916712809382E07027624
chr71280939012809650E07027847
chr71280973712811629E07028194
chr71281163512811761E07030092
chr71275596012756411E071-25132
chr71275645612756688E071-24855
chr71276876712769145E071-12398
chr71280434712804806E07122804
chr71280973712811629E07128194
chr71275596012756411E072-25132
chr71275645612756688E072-24855
chr71276876712769145E072-12398
chr71280358512804303E07222042
chr71280973712811629E07228194
chr71275596012756411E073-25132
chr71275645612756688E073-24855
chr71275040212750596E074-30947
chr71275596012756411E074-25132
chr71275645612756688E074-24855
chr71280916712809382E07427624
chr71280939012809650E07427847
chr71280973712811629E07428194
chr71275496712755949E081-25594
chr71276182112762003E081-19540
chr71276226212763021E081-18522
chr71276333212763382E081-18161
chr71276854612768617E081-12926
chr71276876712769145E081-12398
chr71280870212808878E08127159
chr71280891612808994E08127373
chr71280916712809382E08127624
chr71280939012809650E08127847
chr71280973712811629E08128194
chr71281163512811761E08130092
chr71275496712755949E082-25594
chr71276919012770203E082-11340
chr71280891612808994E08227373
chr71280973712811629E08228194
chr71281163512811761E08230092