rs17633258

Homo sapiens
C>G / C>T
None
Check p-value
SNV (Single Nucleotide Variation)
G=0034 (1043/29982,GnomAD)
G=0044 (221/5008,1000G)
G=0044 (171/3854,ALSPAC)
G=0046 (170/3708,TWINSUK)
chr11:109115147 (GRCh38.p7) (11q22.3)
ND
GWASdb2
1   publication(s)
See rs on genome

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 11NC_000011.10:g.109115147C>G
GRCh38.p7 chr 11NC_000011.10:g.109115147C>T
GRCh37.p13 chr 11NC_000011.9:g.108985874C>G
GRCh37.p13 chr 11NC_000011.9:g.108985874C>T

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.996G=0.004
1000GenomesAmericanSub694C=0.940G=0.060
1000GenomesEast AsianSub1008C=0.976G=0.024
1000GenomesEuropeSub1006C=0.959G=0.041
1000GenomesGlobalStudy-wide5008C=0.956G=0.044
1000GenomesSouth AsianSub978C=0.890G=0.110
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.956G=0.044
The Genome Aggregation DatabaseAfricanSub8720C=0.991G=0.009
The Genome Aggregation DatabaseAmericanSub838C=0.930G=0.070
The Genome Aggregation DatabaseEast AsianSub1620C=0.976G=0.024
The Genome Aggregation DatabaseEuropeSub18502C=0.954G=0.045
The Genome Aggregation DatabaseGlobalStudy-wide29982C=0.965G=0.034
The Genome Aggregation DatabaseOtherSub302C=0.940G=0.060
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.954G=0.046
PMID Title Author Journal
17158188Novel genes identified in a high-density genome wide association study for nicotine dependence.Bierut LJHum Mol Genet

P-Value

SNP ID p-value Traits Study
rs176332587.31E-05nicotine dependence17158188

eQTL of rs17633258 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs17633258 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr1137536123753662E067-40929
chr1137540453754146E067-40445
chr1137541623754343E067-40248
chr1137543853754579E067-40012
chr1138078943808458E06713303
chr1138158333815934E06721242
chr1138160453816125E06721454
chr1138164003816450E06721809
chr1138440793844129E06749488
chr1138441303844218E06749539
chr1137536123753662E068-40929
chr1137540453754146E068-40445
chr1137541623754343E068-40248
chr1137543853754579E068-40012
chr1138031903803352E0688599
chr1138033973803460E0688806
chr1138035283803666E0688937
chr1138071523807248E06812561
chr1138073343807479E06812743
chr1138074833807563E06812892
chr1138076613807701E06813070
chr1138078943808458E06813303
chr1138086293808754E06814038
chr1138087833808976E06814192
chr1138318203832542E06837229
chr1138325853832692E06837994
chr1138073343807479E06912743
chr1138074833807563E06912892
chr1138076613807701E06913070
chr1138078943808458E06913303
chr1138160453816125E06921454
chr1138164003816450E06921809
chr1137536123753662E071-40929
chr1137540453754146E071-40445
chr1137541623754343E071-40248
chr1137543853754579E071-40012
chr1138071523807248E07112561
chr1138073343807479E07112743
chr1138074833807563E07112892
chr1138076613807701E07113070
chr1138078943808458E07113303
chr1138086293808754E07114038
chr1137536123753662E072-40929
chr1137540453754146E072-40445
chr1137541623754343E072-40248
chr1137543853754579E072-40012
chr1138078943808458E07213303
chr1138314743831533E07336883
chr1137528433752917E074-41674
chr1137536123753662E074-40929
chr1137540453754146E074-40445
chr1137541623754343E074-40248
chr1137543853754579E074-40012
chr1138064273806740E07411836
chr1138067853807013E07412194
chr1138071523807248E07412561
chr1138073343807479E07412743
chr1138074833807563E07412892
chr1138078943808458E07413303
chr1138199513820047E08125360
chr1138201153820208E08125524
chr1138160453816125E08221454
chr1138164003816450E08221809









Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr1138173853819636E06722794
chr1138288533831193E06734262
chr1138173853819636E06822794
chr1138288533831193E06834262
chr1138173853819636E06922794
chr1138288533831193E06934262
chr1138173853819636E07022794
chr1138288533831193E07034262
chr1138173853819636E07122794
chr1138288533831193E07134262
chr1138173853819636E07222794
chr1138173853819636E07322794
chr1138288533831193E07334262
chr1138173853819636E07422794
chr1138288533831193E07434262
chr1138173853819636E08122794
chr1138173853819636E08222794
chr1138288533831193E08234262