rs17653713

Homo sapiens
C>A / C>T
None
Check p-value
SNV (Single Nucleotide Variation)
T=0053 (1604/29964,GnomAD)
T=0051 (255/5008,1000G)
chr10:113986660 (GRCh38.p7) (10q25.3)
AD
GWASdb2
1   publication(s)
See rs on genome
3 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 10NC_000010.11:g.113986660C>A
GRCh38.p7 chr 10NC_000010.11:g.113986660C>T
GRCh37.p13 chr 10NC_000010.10:g.115746419C>A
GRCh37.p13 chr 10NC_000010.10:g.115746419C>T

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.967A=0.000
1000GenomesAmericanSub694C=0.970A=0.00,
1000GenomesEast AsianSub1008C=0.897A=0.000
1000GenomesEuropeSub1006C=0.925A=0.010
1000GenomesGlobalStudy-wide5008C=0.946A=0.003
1000GenomesSouth AsianSub978C=0.980A=0.00,
The Genome Aggregation DatabaseAfricanSub8720C=0.964A=0.002
The Genome Aggregation DatabaseAmericanSub838C=0.960A=0.00,
The Genome Aggregation DatabaseEast AsianSub1620C=0.909A=0.000
The Genome Aggregation DatabaseEuropeSub18484C=0.933A=0.006
The Genome Aggregation DatabaseGlobalStudy-wide29964C=0.941A=0.004
The Genome Aggregation DatabaseOtherSub302C=0.950A=0.00,
PMID Title Author Journal
24277619ALDH2 is associated to alcohol dependence and is the major genetic determinant of "daily maximum drinks" in a GWAS study of an isolated rural Chinese sample.Quillen EEAm J Med Genet B Neuropsychiatr Genet

P-Value

SNP ID p-value Traits Study
rs176537130.000354alcohol dependence24277619

eQTL of rs17653713 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs17653713 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr103628100736281068E082-12089
chr103628113336281317E082-11840
chr103628141636281526E082-11631