rs17665021

Homo sapiens
T>G
None
Check p-value
SNV (Single Nucleotide Variation)
G=0037 (1131/29918,GnomAD)
G=0034 (1008/29118,TOPMED)
G=0020 (101/5008,1000G)
G=0049 (188/3854,ALSPAC)
G=0060 (224/3708,TWINSUK)
chr18:27642247 (GRCh38.p7) (18q12.1)
ND
GWASdb2
1   publication(s)
See rs on genome
14 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 18NC_000018.10:g.27642247T>G
GRCh37.p13 chr 18NC_000018.9:g.25222211T>G

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.995G=0.005
1000GenomesAmericanSub694T=0.940G=0.060
1000GenomesEast AsianSub1008T=0.999G=0.001
1000GenomesEuropeSub1006T=0.950G=0.050
1000GenomesGlobalStudy-wide5008T=0.980G=0.020
1000GenomesSouth AsianSub978T=0.990G=0.010
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.951G=0.049
The Genome Aggregation DatabaseAfricanSub8728T=0.989G=0.011
The Genome Aggregation DatabaseAmericanSub836T=0.960G=0.040
The Genome Aggregation DatabaseEast AsianSub1572T=1.000G=0.000
The Genome Aggregation DatabaseEuropeSub18480T=0.947G=0.052
The Genome Aggregation DatabaseGlobalStudy-wide29918T=0.962G=0.037
The Genome Aggregation DatabaseOtherSub302T=0.880G=0.120
Trans-Omics for Precision MedicineGlobalStudy-wide29118T=0.965G=0.034
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.940G=0.060
PMID Title Author Journal
19268276Genome-wide association study of smoking initiation and current smoking.Vink JMAm J Hum Genet

P-Value

SNP ID p-value Traits Study
rs176650216.11E-05nicotine smoking19268276

eQTL of rs17665021 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs17665021 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr182524209225242546E06919881
chr182524258625242707E06920375
chr182518447625185721E070-36490
chr182524071925240823E07018508
chr182524135125242019E07019140
chr182524209225242546E07019881
chr182524135125242019E07119140
chr182524209225242546E07119881
chr182524135125242019E07219140
chr182524209225242546E07219881
chr182524258625242707E07220375
chr182524135125242019E07419140
chr182524209225242546E07419881
chr182518447625185721E082-36490