SNP Detail Info-rs17667691

Organism: Homo sapiens

Alleles: G>A

Gene : Feature

CCDC178 : Intron Variant

p-value: Check p-value

Variation Type: SNV (Single Nucleotide Variation)

Frequency:

A=0057 (1726/29952,GnomAD)
A=0058 (1696/29118,TOPMED)
A=0034 (168/5008,1000G)
A=0085 (326/3854,ALSPAC)
A=0091 (336/3708,TWINSUK)

Position: chr18:33198122 (GRCh38.p7) (18q12.1)

Phenotype: ND

Dataset:

GWASdb2

Publications: 1 publication(s)

Genomic View: See rs on genome

Enhancer: 2 Enhancers around

Promoter: 0 Promoter around

Sequence Name	Change(s)
GRCh38.p7 chr 18	NC_000018.10:g.33198122G>A
GRCh37.p13 chr 18	NC_000018.9:g.30778086G>A

Molecule type	Change	Amino acid[Codon]	SO Term
CCDC178 transcript variant 1	NM_001105528.1:c.	N/A	Intron Variant
CCDC178 transcript variant 3	NM_001308126.1:c.	N/A	Intron Variant
CCDC178 transcript variant 2	NM_198995.2:c.	N/A	Intron Variant
CCDC178 transcript variant X4	XM_011525948.1:c.	N/A	Intron Variant
CCDC178 transcript variant X5	XM_011525951.1:c.	N/A	Intron Variant
CCDC178 transcript variant X1	XM_017025721.1:c.	N/A	Intron Variant
CCDC178 transcript variant X2	XM_017025722.1:c.	N/A	Intron Variant
CCDC178 transcript variant X3	XM_017025723.1:c.	N/A	Intron Variant
CCDC178 transcript variant X6	XM_017025724.1:c.	N/A	Intron Variant
CCDC178 transcript variant X7	XM_017025725.1:c.	N/A	Intron Variant
CCDC178 transcript variant X8	XM_011525954.2:c.	N/A	Genic Downstream Transcript Variant
CCDC178 transcript variant X9	XM_011525955.1:c.	N/A	Genic Downstream Transcript Variant

Study	Population	Group	Sample #	Ref Allele	Alt Allele
1000Genomes	African	Sub	1322	G=0.998	A=0.002
1000Genomes	American	Sub	694	G=0.960	A=0.040
1000Genomes	East Asian	Sub	1008	G=1.000	A=0.000
1000Genomes	Europe	Sub	1006	G=0.914	A=0.086
1000Genomes	Global	Study-wide	5008	G=0.966	A=0.034
1000Genomes	South Asian	Sub	978	G=0.950	A=0.050
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	G=0.915	A=0.085
The Genome Aggregation Database	African	Sub	8720	G=0.985	A=0.015
The Genome Aggregation Database	American	Sub	832	G=0.960	A=0.040
The Genome Aggregation Database	East Asian	Sub	1618	G=1.000	A=0.000
The Genome Aggregation Database	Europe	Sub	18480	G=0.917	A=0.082
The Genome Aggregation Database	Global	Study-wide	29952	G=0.942	A=0.057
The Genome Aggregation Database	Other	Sub	302	G=0.890	A=0.110
Trans-Omics for Precision Medicine	Global	Study-wide	29118	G=0.941	A=0.058
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	G=0.909	A=0.091

PMID	Title	Author	Journal
20158304	A genomewide association study of nicotine and alcohol dependence in Australian and Dutch populations.	Lind PA	Twin Res Hum Genet

SNP ID	p-value	Traits	Study
rs17667691	7.69E-06	alcohol and nictotine co-dependence	20158304

Position (v37)	eGene	GeneID	Variant	p-value	TSS	Tissue
There is no eQTL annotation for this SNP

Probe ID	Position	Gene	beta	p-value
There is no meQTL annotation for this SNP

Chromosome	Start	End	Region	Distance ( -/+ : Up/Downstream )
chr18	30790601	30790817	E068	12515
chr18	30811849	30812463	E072	33763

rs17667691