rs17674853

Homo sapiens
A>G
None
Check p-value
SNV (Single Nucleotide Variation)
G=0281 (8419/29894,GnomAD)
G=0246 (7172/29118,TOPMED)
G=0245 (1228/5008,1000G)
G=0309 (1190/3854,ALSPAC)
G=0309 (1147/3708,TWINSUK)
chr17:68755881 (GRCh38.p7) (17q24.2)
AD
GWASdb2
1   publication(s)
See rs on genome
79 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 17NC_000017.11:g.68755881A>G
GRCh37.p13 chr 17NC_000017.10:g.66752022A>G

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322A=0.783G=0.217
1000GenomesAmericanSub694A=0.720G=0.280
1000GenomesEast AsianSub1008A=0.792G=0.208
1000GenomesEuropeSub1006A=0.691G=0.309
1000GenomesGlobalStudy-wide5008A=0.755G=0.245
1000GenomesSouth AsianSub978A=0.770G=0.230
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854A=0.691G=0.309
The Genome Aggregation DatabaseAfricanSub8706A=0.797G=0.203
The Genome Aggregation DatabaseAmericanSub836A=0.690G=0.310
The Genome Aggregation DatabaseEast AsianSub1608A=0.763G=0.237
The Genome Aggregation DatabaseEuropeSub18442A=0.678G=0.321
The Genome Aggregation DatabaseGlobalStudy-wide29894A=0.718G=0.281
The Genome Aggregation DatabaseOtherSub302A=0.720G=0.280
Trans-Omics for Precision MedicineGlobalStudy-wide29118A=0.753G=0.246
UK 10K study - TwinsTWIN COHORTStudy-wide3708A=0.691G=0.309
PMID Title Author Journal
22072270Genome-wide association study identifies 5q21 and 9p24.1 (KDM4C) loci associated with alcohol withdrawal symptoms.Wang KSJ Neural Transm (Vienna)

P-Value

SNP ID p-value Traits Study
rs176748532.46E-05alcohol withdrawal symptoms22072270

eQTL of rs17674853 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs17674853 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr176676873866768788E06716716
chr176677245666774906E06720434
chr176677989266780594E06727870
chr176678905866789665E06737036
chr176678979266790407E06737770
chr176679067766791563E06738655
chr176677245666774906E06820434
chr176677989266780594E06827870
chr176678062566780809E06828603
chr176678786066788790E06835838
chr176678879966788889E06836777
chr176678894066789051E06836918
chr176678905866789665E06837036
chr176678979266790407E06837770
chr176679962566799891E06847603
chr176679990766800011E06847885
chr176678786066788790E06935838
chr176678879966788889E06936777
chr176678894066789051E06936918
chr176678905866789665E06937036
chr176678979266790407E06937770
chr176679962566799891E06947603
chr176679990766800011E06947885
chr176676873866768788E07116716
chr176676883966768970E07116817
chr176677245666774906E07120434
chr176677528166775352E07123259
chr176677667966777024E07124657
chr176677989266780594E07127870
chr176678062566780809E07128603
chr176678786066788790E07135838
chr176678879966788889E07136777
chr176678894066789051E07136918
chr176678905866789665E07137036
chr176678979266790407E07137770
chr176679067766791563E07138655
chr176679334566793493E07141323
chr176679374366793787E07141721
chr176679941166799517E07147389
chr176679962566799891E07147603
chr176679990766800011E07147885
chr176677245666774906E07220434
chr176677989266780594E07227870
chr176678786066788790E07235838
chr176678879966788889E07236777
chr176678894066789051E07236918
chr176678905866789665E07237036
chr176678979266790407E07237770
chr176679067766791563E07238655
chr176677989266780594E07327870
chr176678905866789665E07337036
chr176676805666768691E07416034
chr176676873866768788E07416716
chr176676883966768970E07416817
chr176677245666774906E07420434
chr176677970066779883E07427678
chr176677989266780594E07427870
chr176678062566780809E07428603
chr176678786066788790E07435838
chr176678879966788889E07436777
chr176678894066789051E07436918
chr176678905866789665E07437036
chr176678979266790407E07437770
chr176679067766791563E07438655
chr176670220566702255E081-49767
chr176670235366702403E081-49619
chr176670290766703770E081-48252
chr176673396066734107E081-17915
chr176673413166734555E081-17467
chr176673455866734693E081-17329
chr176673493166734985E081-17037
chr176673503766735203E081-16819
chr176679941166799517E08147389
chr176679962566799891E08147603
chr176679990766800011E08147885
chr176680112166801161E08149099
chr176680124066801752E08149218
chr176670235366702403E082-49619
chr176670290766703770E082-48252